MRF-Logo2019-Horizontal-RGB
Good news on NYE – Ipi response!
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Good news on NYE – Ipi response!

› Forums › General Melanoma Community › Good news on NYE – Ipi response!

  • Post
    • December 31, 2015 at 1:59 pm
    bonusfries
    Participant

      I had progressed while on BRAF + MEK (2cm adrenal mets), and since the new growth was limited and small, we did the 4 infusion cycle of ipi starting in the beginning of August.

      An interview I had read from Celeste's blog said most people who progress on BRAF don't respond to ipi, so I did not have high hopes for this treatment.

      My last infusion was on October 9th. While my side effects were rather impactful, my blood work and overall health were good throughout so we waited as long as possible for follow-up scans.

      My follow-up CT shows no traces of the mets, nor did it find anything new! The side effects were well worth that radiology report.

      Clean scans for all in 2016!

      Jeff

    Viewing 11 reply threads
    • Replies
        • December 31, 2015 at 2:22 pm
        mjanssentx
        Participant

          Jeff – that is great news….have a great new years…Michel

          • December 31, 2015 at 2:22 pm
          mjanssentx
          Participant

            Jeff – that is great news….have a great new years…Michel

            • December 31, 2015 at 2:22 pm
            mjanssentx
            Participant

              Jeff – that is great news….have a great new years…Michel

              • December 31, 2015 at 4:51 pm
              Bubbles
              Participant

                Oh, Jeff that is wonderful news indeed! (Not the side effects of course, but the great results!)

                I am a little unsure about what gave you your concerns about a response to ipi after failing BRAFi. Most data report response to ipi in that circumstance to be about the same as when taking ipi for the first time:  

                http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2014/11/data-on-brafi-combos-and-effects-of-ipi.html

                The contradiction in data regarding response rates usually revolves around whether to take anti-PD1 or ipi first in order to achieve the best response.  But either way…..your news is excellent! 

                I wish you my best and a wonderful 2016!  Celeste

                • December 31, 2015 at 4:51 pm
                Bubbles
                Participant

                  Oh, Jeff that is wonderful news indeed! (Not the side effects of course, but the great results!)

                  I am a little unsure about what gave you your concerns about a response to ipi after failing BRAFi. Most data report response to ipi in that circumstance to be about the same as when taking ipi for the first time:  

                  http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2014/11/data-on-brafi-combos-and-effects-of-ipi.html

                  The contradiction in data regarding response rates usually revolves around whether to take anti-PD1 or ipi first in order to achieve the best response.  But either way…..your news is excellent! 

                  I wish you my best and a wonderful 2016!  Celeste

                  • December 31, 2015 at 4:51 pm
                  Bubbles
                  Participant

                    Oh, Jeff that is wonderful news indeed! (Not the side effects of course, but the great results!)

                    I am a little unsure about what gave you your concerns about a response to ipi after failing BRAFi. Most data report response to ipi in that circumstance to be about the same as when taking ipi for the first time:  

                    http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2014/11/data-on-brafi-combos-and-effects-of-ipi.html

                    The contradiction in data regarding response rates usually revolves around whether to take anti-PD1 or ipi first in order to achieve the best response.  But either way…..your news is excellent! 

                    I wish you my best and a wonderful 2016!  Celeste

                    • December 31, 2015 at 9:33 pm
                    Jubes
                    Participant

                      Brilliant!! Thanks for posting. Gives us all hope! 

                      • December 31, 2015 at 9:33 pm
                      Jubes
                      Participant

                        Brilliant!! Thanks for posting. Gives us all hope! 

                        • December 31, 2015 at 9:33 pm
                        Jubes
                        Participant

                          Brilliant!! Thanks for posting. Gives us all hope! 

                          • December 31, 2015 at 10:29 pm
                          Eileensulliv
                          Participant

                            Fantastic news, Jeff! What a great way to start 2016!

                            • December 31, 2015 at 10:29 pm
                            Eileensulliv
                            Participant

                              Fantastic news, Jeff! What a great way to start 2016!

                              • December 31, 2015 at 10:29 pm
                              Eileensulliv
                              Participant

                                Fantastic news, Jeff! What a great way to start 2016!

                            Viewing 11 reply threads
                            • You must be logged in to reply to this topic.
                            About the MRF Patient Forum

                            The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                            The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

                            Popular Topics