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Fever while on Yervoy
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Fever while on Yervoy

› Forums › General Melanoma Community › Fever while on Yervoy

  • Post
    • March 6, 2016 at 1:37 pm
    keepthefaith11
    Participant
      My dad had his second infusion on Wednesday. No issues at all after the first one.

      Yesterday morning he woke with a fever of 101.6. No other symptoms at all. It then went up to 103 in the afternoon but was brought down to 100 with Tylenol.

      Talked to the doctor and she initially suggested ER to check infection, but when I told her there are no other signs she said we could hold off. She said it is a fairly common side effect of Yervoy.

      At 6am it was again 102 but again went down with Tylenol. So hard to know if this is Yervoy related or not. We will go to the cancer clinic tomorrow and get bloodwork done, rather keep him out of the ER though.

      Anybody experience this?

    Viewing 2 reply threads
    • Replies
        • March 6, 2016 at 5:30 pm
        jennunicorn
        Participant

          I looked at my list of side effects that my onc gave me for Yervoy and fever is not listed, I don't recall that being a common side effect for Yervoy. I did not experience any fevers myself. Keep him on Tylenol and definitely get in to see the doctor.

          All the best,

          • March 6, 2016 at 5:30 pm
          jennunicorn
          Participant

            I looked at my list of side effects that my onc gave me for Yervoy and fever is not listed, I don't recall that being a common side effect for Yervoy. I did not experience any fevers myself. Keep him on Tylenol and definitely get in to see the doctor.

            All the best,

              • March 6, 2016 at 8:07 pm
              Jane Hearn
              Participant

                After his first Keytruda treatment, my husband had violent chills and profuse sweating (the evening of the infusion).  Chills continued intermittenly, with sweats more frequent.  On the second day following the treatment, his temperature soared.  I wasn't home, so he couldn't find the thermometer, but he took ibuprofen and it went down quickly.  The next evening I was there, and he began chilling,  I took his temperature and it was 98.  The chills continued and I took his temp again a few minutes later.  It was 101+.  He still didn't want to take any medication.  In just a few more minutes it was 103.8.  I couldn't believe it, so I took it again with another thermometer.  103.8 F.  He took 2 ibuprofen, and it began to drop instantly.  30 minutes later he was sweating profusely and his temperature was 97F.  This occured the following evening, as well.  Hasn't happened since.  He has only had two treatments, though. so this was only a couple of weeks ago. 

                • March 6, 2016 at 8:07 pm
                Jane Hearn
                Participant

                  After his first Keytruda treatment, my husband had violent chills and profuse sweating (the evening of the infusion).  Chills continued intermittenly, with sweats more frequent.  On the second day following the treatment, his temperature soared.  I wasn't home, so he couldn't find the thermometer, but he took ibuprofen and it went down quickly.  The next evening I was there, and he began chilling,  I took his temperature and it was 98.  The chills continued and I took his temp again a few minutes later.  It was 101+.  He still didn't want to take any medication.  In just a few more minutes it was 103.8.  I couldn't believe it, so I took it again with another thermometer.  103.8 F.  He took 2 ibuprofen, and it began to drop instantly.  30 minutes later he was sweating profusely and his temperature was 97F.  This occured the following evening, as well.  Hasn't happened since.  He has only had two treatments, though. so this was only a couple of weeks ago. 

                  • March 6, 2016 at 10:00 pm
                  keepthefaith11
                  Participant
                    Jane, thank you for this. Yes, fever soars very quickly and no other symptoms. Is easily brought down by Tylenol. We are taking him to the clinic tomorrow so they can do some blood work. I am thinking it is Yervoy related with the timing and no symptoms. But checking for other possible causes just in case.

                    It is scary and just like you I used different thermometers thinking the temp must be wrong. It went up to the upper 103’s today. He is upbeat and acts totally normal even at the highest temps.

                    Thank you again!

                    Annie

                    • March 6, 2016 at 10:00 pm
                    keepthefaith11
                    Participant
                      Jane, thank you for this. Yes, fever soars very quickly and no other symptoms. Is easily brought down by Tylenol. We are taking him to the clinic tomorrow so they can do some blood work. I am thinking it is Yervoy related with the timing and no symptoms. But checking for other possible causes just in case.

                      It is scary and just like you I used different thermometers thinking the temp must be wrong. It went up to the upper 103’s today. He is upbeat and acts totally normal even at the highest temps.

                      Thank you again!

                      Annie

                      • March 6, 2016 at 10:00 pm
                      keepthefaith11
                      Participant
                        Jane, thank you for this. Yes, fever soars very quickly and no other symptoms. Is easily brought down by Tylenol. We are taking him to the clinic tomorrow so they can do some blood work. I am thinking it is Yervoy related with the timing and no symptoms. But checking for other possible causes just in case.

                        It is scary and just like you I used different thermometers thinking the temp must be wrong. It went up to the upper 103’s today. He is upbeat and acts totally normal even at the highest temps.

                        Thank you again!

                        Annie

                        • March 6, 2016 at 8:07 pm
                        Jane Hearn
                        Participant

                          After his first Keytruda treatment, my husband had violent chills and profuse sweating (the evening of the infusion).  Chills continued intermittenly, with sweats more frequent.  On the second day following the treatment, his temperature soared.  I wasn't home, so he couldn't find the thermometer, but he took ibuprofen and it went down quickly.  The next evening I was there, and he began chilling,  I took his temperature and it was 98.  The chills continued and I took his temp again a few minutes later.  It was 101+.  He still didn't want to take any medication.  In just a few more minutes it was 103.8.  I couldn't believe it, so I took it again with another thermometer.  103.8 F.  He took 2 ibuprofen, and it began to drop instantly.  30 minutes later he was sweating profusely and his temperature was 97F.  This occured the following evening, as well.  Hasn't happened since.  He has only had two treatments, though. so this was only a couple of weeks ago. 

                          • March 6, 2016 at 10:06 pm
                          keepthefaith11
                          Participant
                            Jenn, it was not listed on our papers either. Very strange since it is all over the internet. The doctor also said it is a side effect which occurs in about 20% of people or so. We are going into the doctor first thing tomorrow. Thank you!
                            • March 6, 2016 at 10:06 pm
                            keepthefaith11
                            Participant
                              Jenn, it was not listed on our papers either. Very strange since it is all over the internet. The doctor also said it is a side effect which occurs in about 20% of people or so. We are going into the doctor first thing tomorrow. Thank you!
                              • March 6, 2016 at 10:33 pm
                              jennunicorn
                              Participant
                                Good to know, hope it goes away for him soon
                                • March 6, 2016 at 10:33 pm
                                jennunicorn
                                Participant
                                  Good to know, hope it goes away for him soon
                                  • March 6, 2016 at 10:33 pm
                                  jennunicorn
                                  Participant
                                    Good to know, hope it goes away for him soon
                                    • March 6, 2016 at 10:06 pm
                                    keepthefaith11
                                    Participant
                                      Jenn, it was not listed on our papers either. Very strange since it is all over the internet. The doctor also said it is a side effect which occurs in about 20% of people or so. We are going into the doctor first thing tomorrow. Thank you!
                                    • March 6, 2016 at 5:30 pm
                                    jennunicorn
                                    Participant

                                      I looked at my list of side effects that my onc gave me for Yervoy and fever is not listed, I don't recall that being a common side effect for Yervoy. I did not experience any fevers myself. Keep him on Tylenol and definitely get in to see the doctor.

                                      All the best,

                                  Viewing 2 reply threads
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