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Technical Terminology in Path Report

Forums Cutaneous Melanoma Community Technical Terminology in Path Report

  • Post
    Dore
    Participant

      I recently had a biopsy of a mole on my stomach.  I am scheduled for WLE on August 9.  The nurse told me that basically it was as close to a melanoma as it could be without being a melanoma.  After reading the path report, I am freaking out a bit because it pretty much says they can't exclude the possibility of it being a melanoma.  Any help deciphering the report would be greatly appreciated!!

      ————————————

      Diagnosis:

      -Compound Dysplastic Nevus, Severe Atypia

      -The lesion involves the deep and peripheral edges of the biopsy.

      ​Please note:  The specimen shows concerning cytologic and architectural atypia. The atypical melanocytes are large and epithelioid and there are patterns of incomplete pagetoid spread. In addition a mitosis was identified within the junctional component. We cannot entirely exclude that the changes represent a partial biopsy of melanoma and wide full thickness re-excision with adequate margins to ensure complete removal and to allow further pathologic evaluation is recommended.

      Microscopic Examination:
      Sections show a thin biopsy of skin. There is proliferation of atypical melanocytes both singly and within nests at the dermo-epidermal junction and singly and within nests in the underlying dermis. The melanocytes are large epithelioid cells showing prominent villi. An occasional mitosis was identified at the dermal junction. There are focal patterns of incomplete pagetoid spread. Lesional cells are highlighted on Melan A stained sections.
      —————————————
      Thanks in advance for any insight you can offer on this report!

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    • Replies
        Dore
        Participant

          I forgot to include that I am a 37y/o female- single mom to 3 little boys who are 1, 5, & 10.  I have numerous moles and freckles.  I am fair skinned and have had more blistering sunburns than I have fingers and toes. Should I ask the doctor if she would give me a full body exam to try to locate any other worrisome areas? I only went in to the dermatologist for a consultation regarding botox treatments for my cranio-facial hiperhydrosis and luckily I thought to show her the mole on my stomach that seemed to be changing in color and just didn't look right to me.

            Janner
            Participant

              Changing moles are the ones to watch for!!!  You can certainly see a derm for a full body exam but I suggest taking photos yourself and watching for change just as you did.  Derm's don't get to see the progression and most moles will be stable across your lifetime.  No need to have lots of unnecessary biopsies.  I'm a big believer in just removing things that change.  (I've had 3 melanomas over the past 25 years and still here and stage 1).

              Typically they take 5mm margins when removing severely atypical lesions.  If you have melanoma in situ (next step up), they remove with 5mm margins.  So…. the diagnosis is not melanoma (much better especially if they repeal ACA and pre-existing conditions come into play again).  But the treatment is the same so you are covered.  Don't freak out too much, you caught this, it was removed and gave you a wake up call to be more vigilant in the future.  Stay sun smart especially with those kiddos!

              A
              Participant

                I agree with Janner's recommendatios. However, I would send the slides for the second opinion to the makor academic institution just to be safe and ebsure that 5 mm margins are sufficient.

                Dore
                Participant

                  Thank you so much for your insight and advice!

                  Dore
                  Participant

                    and I've never heard of the makor institute that was mentioned.  I will look into it though!  Thank you both again!

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