The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

New here – help understanding pathology report

Forums Cutaneous Melanoma Community New here – help understanding pathology report

  • Post
    Sclemens1114
    Participant

      I recently had several moles removed, with 2 coming back showing some level of atypia; one mild and one moderate. Below is the report for each:

       

      1). There is a letiginous and junctional proliferation of melanocytes with a mild degree of cytologic stylus. There a underlying dermal fibroplasia with a lymphocytic infiltrate. There is pigment incontinence with scattered melanophages notes in the superficial dermis. On limited margin evaluation, the edges appear free.

       

      2). Melanocytes are present at the junction and within the dermis. There is an aberrant architecture with associated strolls fibroplasia and a lymphocytic host response. Upward growth of single cells is not co spacious but there is moderate atypical of the melanocytic cells. There are changes that suggest that this lesion has been previously irritated. Few pageloid melanocytes are noted, possibly related to the irritation. The deep margin is involved.  

       

      My my questions are:  do these seem like standard reports, or does anything unusual stand out?  I'm especially concern d with the terms "lymphocytic infiltrate" and "lymphocytic host response". What do these mean?  What does "deep margins involved" mean?  Is this a standard term when margins are unclear, or do the abnormal cells extend deeper than is typical? 

    Viewing 0 reply threads
    • Replies
        UBContributor
        Participant

          Each situatioin is so different it is difficult to say what is standard. May be you could seek another Dr (dermatology oncologist only) for second opnion. This is what I would do. 

      Viewing 0 reply threads
      • You must be logged in to reply to this topic.
      About the MRF Patient Forum

      The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

      The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

      Popular Topics