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Good News

› Forums › Cutaneous Melanoma Community › Good News

  • Post
    • September 8, 2017 at 11:19 pm
    CindyJ
    Participant

      Hello all ~ I wanted to share my Mom's good news regarding the trial study using Genomics. Background, she had a deep ulcerated melanoma on bottom of her foot and spread to toes. Removal, skin graft, and CLND in groin and pelvis. Wait and see. A year and a half later fast growing melanoma found in lymph node further up pelvic chain (iliac) and possible lung met.

      She received three Pembro infusions (immunotheraphy) beginning in late April then was switched to Ibrance (target therapy) in July. (The Onc didn't believe Pembro was working). After two pill cycles of Ibrance, her pelvis tumor has shrunk in half with SUV going from 17+ down to 6.3 and her lung nodule shrank with no uptake (could have been infection).

      During prior testing, she was found to have three separate mutations that current cancer drugs are available for. Ibrance is a breast cancer drug that stops cancer growth by inhibiting CDK 4/6, she is CCDN1 amplified.

      The Onc was rather shocked it worked so well so fast, and I'm not all that certain that Pembro didn't play a role, but we're both so elated. If immunotheraphy doesn't work for you, you may have a mutation that can be treated. Seems to be the next great step in cancer treatment. Best wishes everyone!

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    • Replies
        • September 9, 2017 at 1:42 am
        Jahendry12
        Participant

          Great news!  Thanks for keeping us updated. Praying for continued good results. 

            • September 9, 2017 at 9:31 pm
            CindyJ
            Participant

              Thank you, I appreciate your kindness!

            • September 10, 2017 at 1:31 am
            BrianP
            Participant

              Congrats Cindy.  Thanks for posting.  Great advice for folks to think about.

              • September 10, 2017 at 4:52 pm
              sister of patient
              Participant

                Thank you for posting this Cindy. News about different treatment combos that work is really exciting and it's **GREAT** that it's working for your mom!! So pleased for both of you!! Best wishes!

                Barb

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