LDH went from 164 to 581 in 2 weeks. Need to be scared? (4st)
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LDH went from 164 to 581 in 2 weeks. Need to be scared? (4st)

› Forums › General Melanoma Community › LDH went from 164 to 581 in 2 weeks. Need to be scared? (4st)

  • Post
    • March 17, 2021 at 9:01 am
    Ekaterina
    Participant
      Hello everyone 🙂

      Your stories and advice are very helpful, so again I hope for the wisdom of the forum. A little background. Mom had a melanoma mole cut out in 2018. In March 2018, metastasis to the lymph node – it was also excised and prescribed opdivo. We went through 10 months of treatment and were interrupted due to a lack of medicine in the city.

      All PET / CT scans have been clear since the removal of the lymph nodes (for 2 years), but 2 weeks ago the examination found 4 small lesions with SUVs ranging from 1.6 to 5.5 (1 lymph node, 2 soft tissue, 1 bone). We immediately passed LDH – 164. However, today new results came – LDH jumped to 581 in just 2 weeks.

      How scary is it? Is this a very high level? I managed to read that a high LDH gives a negative prognosis for the effectiveness of immunotherapy – is this true? In the coming week, we should receive the first combo shot (Opdivo + Ervoy) and now we are worried that this reduces the chances for it success.

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        • March 17, 2021 at 11:09 am
        Ekaterina
        Participant
          We also just noticed a postscript for the analysis:
          "Blood hemolysis! The results may be unreliable."
          Did anyone have this? We will redo the analysis tomorrow.
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