What treatments are out in US, but not Canada
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What treatments are out in US, but not Canada

› Forums › General Melanoma Community › What treatments are out in US, but not Canada

  • Post
    • August 11, 2011 at 5:25 am
    tricialeigh44
    Participant

      My Mom has finished 3 rounds of IL2 in Buffalo and is now moving on to IPI. I am just wondering if we can somehow pool all of the melonama treatments available in Canada vs the US. What have been the most effective treatments.

      My mum has stage 4 melanoma that has not spread past her lungs.

      Thanks in advance

      Tricia

      My Mom has finished 3 rounds of IL2 in Buffalo and is now moving on to IPI. I am just wondering if we can somehow pool all of the melonama treatments available in Canada vs the US. What have been the most effective treatments.

      My mum has stage 4 melanoma that has not spread past her lungs.

      Thanks in advance

      Tricia

    Viewing 1 reply thread
    • Replies
        • August 11, 2011 at 10:59 am
        FormerCaregiver
        Participant

          Tricia, can you tell us a bit about your mum's history with melanoma? Perhaps you could
          update your profile page, as this will really help us to help you better.

          Ipi (now called Yervoy) is probably the most effective drug that we have at the moment.
          Other treatments that are worth considering include Braf and similar inhibitors.

          However, I feel that TIL treatment (adoptive cell therapy) is the most promising therapy
          that is available. For more info see:
          http://www.melanoma.org/community/mpip-melanoma-patients-information-page/til-treatment-adoptive-cell-therapy-clinical-trial

          It appears that the US has the biggest range of melanoma treatments in the world. I
          think that your options could be fairly limited in Canada, but I am not certain of what
          is available at the moment. Clinical trials are always worth considering. See:
          http://www.clinicaltrials.gov/ct2/results?term=&recr=Open&rslt=&type=&cond=melanoma&intr=&outc=&lead=&spons=&id=&state1=&cntry1=NA%3ACA&state2=&cntry2=&state3=&cntry3=&locn=&gndr=&rcv_s=&rcv_e=&lup_s=&lup_e=

          Hope this helps.

          Frank from Australia

          • August 11, 2011 at 10:59 am
          FormerCaregiver
          Participant

            Tricia, can you tell us a bit about your mum's history with melanoma? Perhaps you could
            update your profile page, as this will really help us to help you better.

            Ipi (now called Yervoy) is probably the most effective drug that we have at the moment.
            Other treatments that are worth considering include Braf and similar inhibitors.

            However, I feel that TIL treatment (adoptive cell therapy) is the most promising therapy
            that is available. For more info see:
            http://www.melanoma.org/community/mpip-melanoma-patients-information-page/til-treatment-adoptive-cell-therapy-clinical-trial

            It appears that the US has the biggest range of melanoma treatments in the world. I
            think that your options could be fairly limited in Canada, but I am not certain of what
            is available at the moment. Clinical trials are always worth considering. See:
            http://www.clinicaltrials.gov/ct2/results?term=&recr=Open&rslt=&type=&cond=melanoma&intr=&outc=&lead=&spons=&id=&state1=&cntry1=NA%3ACA&state2=&cntry2=&state3=&cntry3=&locn=&gndr=&rcv_s=&rcv_e=&lup_s=&lup_e=

            Hope this helps.

            Frank from Australia

              • August 11, 2011 at 12:17 pm
              Lisa13
              Participant

                Hi Tricia,

                I'm from Canada (Toronto) and also have Stage 4 which hasn't spread beyond the lungs.  After failing dacarabazine, I just started ipi (Yervoy) yesterday. Canada doesn't seem to have alot of treatment options, but there are some options available in clinical trials and newer ones becoming available in the next few months (which are already in the U.S.). For example, TIL treatment is in the experimental stages right now and will be available for human use in 4-6 months. Also, Anti PD-1 is also to become available later this year. Even though we're behind, we're getting there.  IL-2 and Leukine treatments arn't available in Canada and we have to travel in order to get them.

                Best of luck to your Mom

                Lisa

                 

                • August 11, 2011 at 12:17 pm
                Lisa13
                Participant

                  Hi Tricia,

                  I'm from Canada (Toronto) and also have Stage 4 which hasn't spread beyond the lungs.  After failing dacarabazine, I just started ipi (Yervoy) yesterday. Canada doesn't seem to have alot of treatment options, but there are some options available in clinical trials and newer ones becoming available in the next few months (which are already in the U.S.). For example, TIL treatment is in the experimental stages right now and will be available for human use in 4-6 months. Also, Anti PD-1 is also to become available later this year. Even though we're behind, we're getting there.  IL-2 and Leukine treatments arn't available in Canada and we have to travel in order to get them.

                  Best of luck to your Mom

                  Lisa

                   

                  • August 11, 2011 at 6:18 pm
                  lyndaloo
                  Participant

                    Hi Lisa, we also live in Canada, my husband (stage 4) just tested negative for BRAF.  In order to eligible for the ipi he must try chemo first, how many tries did you do of Decarbazine before you were allowed the ipi?  The TIL and Anti PD-1, do you have to be BRAF positive for these? I hope you have a positive outcome with the ipi. I am fearful they may pull the ipi before he is eligible to enroll in the study.

                    All the best,

                    lyndaloo

                    • August 12, 2011 at 2:07 am
                    FormerCaregiver
                    Participant

                      Lyndaloo, I would just like to chime in here. As far as I know, TIL treatment is
                      certainly possible without being BRAF positive. However, this therapy has eligibility
                      criteria that can be quite strict and therefore not everyone might be accepted.

                      Here is a link to a previous thread about anti-pd-1:
                      http://www.melanoma.org/community/mpip-melanoma-patients-information-page/anti-pd-1-what-it-and-who-it

                      Best wishes

                      Frank from Australia

                      • August 12, 2011 at 2:07 am
                      FormerCaregiver
                      Participant

                        Lyndaloo, I would just like to chime in here. As far as I know, TIL treatment is
                        certainly possible without being BRAF positive. However, this therapy has eligibility
                        criteria that can be quite strict and therefore not everyone might be accepted.

                        Here is a link to a previous thread about anti-pd-1:
                        http://www.melanoma.org/community/mpip-melanoma-patients-information-page/anti-pd-1-what-it-and-who-it

                        Best wishes

                        Frank from Australia

                        • August 11, 2011 at 6:18 pm
                        lyndaloo
                        Participant

                          Hi Lisa, we also live in Canada, my husband (stage 4) just tested negative for BRAF.  In order to eligible for the ipi he must try chemo first, how many tries did you do of Decarbazine before you were allowed the ipi?  The TIL and Anti PD-1, do you have to be BRAF positive for these? I hope you have a positive outcome with the ipi. I am fearful they may pull the ipi before he is eligible to enroll in the study.

                          All the best,

                          lyndaloo

                    Viewing 1 reply thread
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