› Forums › Cutaneous Melanoma Community › Question about ALDARA -Jim Breitfeller or anyone
- This topic has 6 replies, 3 voices, and was last updated 14 years, 1 month ago by
jimjoeb.
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- August 12, 2011 at 12:03 am
Jim or anyone with knowledge about aldara,
Jim,you mentioned in a previous post:
Jim or anyone with knowledge about aldara,
Jim,you mentioned in a previous post:
"Imiquimod also has antitumor activity, which might stem from the drug’s ability to stimulate a cell-mediated immune response. Application of imiquimod also leads to the release of IL-12, tumor necrosis factor α, and interferon α, which inhibit angiogenesis and increase cytotoxic T cells and natural killer cells.Imiquimod also up-regulates IL-2, which down-regulates IL-10, thus reversing the suppression of antitumor Tcells.
You can apply the cream to your face to stimulate the local immune system at the point of contact. "
Best regards,
Jimmy B
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I have heard of aldara and I have the following questions about aldara?
Does aldara work on Subq's (lumps) "beneath" the skin or just "skin" cutaneous based melanoma.
I have a small lump under my skin but the lump is poking through my skin. Would aldara be effective on my subq lump if I rubbed aldara into the lump?? There is no melanoma color on the top of the lump…just skin color.
Thanks for your help.
Mary
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- August 12, 2011 at 11:24 am
Mary, Imiquimod may work for you. I would suggest that you get approval through your oncologist. It is a prescription cream that you appy to the target area. Some Patients have a violent reaction. Care must be taken while using it. Follow the instructions to a T.
If your sub Q's are close to the surface, Imiquimod may work.
Take care
Jimmy B
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- August 12, 2011 at 11:24 am
Mary, Imiquimod may work for you. I would suggest that you get approval through your oncologist. It is a prescription cream that you appy to the target area. Some Patients have a violent reaction. Care must be taken while using it. Follow the instructions to a T.
If your sub Q's are close to the surface, Imiquimod may work.
Take care
Jimmy B
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- August 12, 2011 at 2:16 pm
Although it has been used for Basal cell, actinic keratosis, and more rarely for some forms of lentigo maligna melanoma, you may wish to discuss with your doctor if you should use this personally for melanoma sub q's. When possible, surgery is the best option, and if I recall correctly, Jim uses it as a follow up post surgery on that area, and he applies it to the primary tumor site every 3 months for about 5 days.
So, one might consider Imiquimod post surgery, but from my reading, the data is limited on it's effectiveness as well.
Michael
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- August 12, 2011 at 2:16 pm
Although it has been used for Basal cell, actinic keratosis, and more rarely for some forms of lentigo maligna melanoma, you may wish to discuss with your doctor if you should use this personally for melanoma sub q's. When possible, surgery is the best option, and if I recall correctly, Jim uses it as a follow up post surgery on that area, and he applies it to the primary tumor site every 3 months for about 5 days.
So, one might consider Imiquimod post surgery, but from my reading, the data is limited on it's effectiveness as well.
Michael
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Tagged: cutaneous melanoma
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