Zelboraf

  I have been on Zelboraf since 9/12/11. The side effects have been not really  too bad.At first minor joint pain for 2or3 days  in the foot or shoulder That stopped after a few weeks.Occasionally you will get a occasional case of the runs.You do get plenty of gas though.eventually you will loose your hair.Definitely stay covered up when going outdoors.All in all very doable.The Zelboraf worked within 2 days and is continueing to work Thank God. All the best to you . Al

  I have been on Zelboraf since 9/12/11. The side effects have been not really  too bad.At first minor joint pain for 2or3 days  in the foot or shoulder That stopped after a few weeks.Occasionally you will get a occasional case of the runs.You do get plenty of gas though.eventually you will loose your hair.Definitely stay covered up when going outdoors.All in all very doable.The Zelboraf worked within 2 days and is continueing to work Thank God. All the best to you . Al

  I have been on Zelboraf since 9/12/11. The side effects have been not really  too bad.At first minor joint pain for 2or3 days  in the foot or shoulder That stopped after a few weeks.Occasionally you will get a occasional case of the runs.You do get plenty of gas though.eventually you will loose your hair.Definitely stay covered up when going outdoors.All in all very doable.The Zelboraf worked within 2 days and is continueing to work Thank God. All the best to you . Al

I have a bunch of side effects, but not sure if they are due to craniotomy, drugs (Zelboraf & steroids) or disease.  My side effects are: fatigue (big problem some days.  I am usually a very active person – I run, lift weights, but lately I have been sleeping all day), problems with my hearing (constant ringing in left ear and hearing loss), loss of vison in right eye, and loss of taste.  I take 8 pills a day too.  

David

I have a bunch of side effects, but not sure if they are due to craniotomy, drugs (Zelboraf & steroids) or disease.  My side effects are: fatigue (big problem some days.  I am usually a very active person – I run, lift weights, but lately I have been sleeping all day), problems with my hearing (constant ringing in left ear and hearing loss), loss of vison in right eye, and loss of taste.  I take 8 pills a day too.  

David

I have a bunch of side effects, but not sure if they are due to craniotomy, drugs (Zelboraf & steroids) or disease.  My side effects are: fatigue (big problem some days.  I am usually a very active person – I run, lift weights, but lately I have been sleeping all day), problems with my hearing (constant ringing in left ear and hearing loss), loss of vison in right eye, and loss of taste.  I take 8 pills a day too.  

David

I am part of the phase II trial and have been taking the full 960mg dose twice a day continuously since March 2010. (My profile has information concerning tumor reduction if interested.)  As to side effects, I would have to admit that they were never debilitating but at times some were very painful; some came on very quick and I still have them and some have pretty much disappeared.

Almost immediately, I developed a rash on my entire body but never on my face and the rash is still evident today. Extreme photosensitivity also was quick to start and continues. Sunscreen, special SPF rated clothing and wide brim hats will be some of your best friends.

I’m not sure when it started, but I did have body hair loss.  I’m 65 and the hair on my head was already thinning so I do not know if Zelboraf contributed to additional head hair loss but it definitely did not all fall out although the texture did change. Today body hair has mostly returned although much thinner.

I developed many small warts on different parts of my body. Those that were sore were taken off and biopsied. One such wart turned out to be a cutaneous squamous cell carcinoma that was successfully removed with Mohs surgery.

I developed neuropathy in both feet and it was very painful for a time. I got new shoes (much wider) and today I only have mild discomfort from time to time.  There was also a period when my ankles and feet were swollen. The swelling is much better and is just a minor annoyance on my left side.

As to joint pain, there are mornings that it is difficult to get going especially up and down stairs. Similar to the head hair loss, my knees were sore prior to starting Zelboraf (arthritis?) so I am not sure of the cause.

Best of luck to you.

Dick

I am part of the phase II trial and have been taking the full 960mg dose twice a day continuously since March 2010. (My profile has information concerning tumor reduction if interested.)  As to side effects, I would have to admit that they were never debilitating but at times some were very painful; some came on very quick and I still have them and some have pretty much disappeared.

Almost immediately, I developed a rash on my entire body but never on my face and the rash is still evident today. Extreme photosensitivity also was quick to start and continues. Sunscreen, special SPF rated clothing and wide brim hats will be some of your best friends.

I’m not sure when it started, but I did have body hair loss.  I’m 65 and the hair on my head was already thinning so I do not know if Zelboraf contributed to additional head hair loss but it definitely did not all fall out although the texture did change. Today body hair has mostly returned although much thinner.

I developed many small warts on different parts of my body. Those that were sore were taken off and biopsied. One such wart turned out to be a cutaneous squamous cell carcinoma that was successfully removed with Mohs surgery.

I developed neuropathy in both feet and it was very painful for a time. I got new shoes (much wider) and today I only have mild discomfort from time to time.  There was also a period when my ankles and feet were swollen. The swelling is much better and is just a minor annoyance on my left side.

As to joint pain, there are mornings that it is difficult to get going especially up and down stairs. Similar to the head hair loss, my knees were sore prior to starting Zelboraf (arthritis?) so I am not sure of the cause.

Best of luck to you.

Dick

I am part of the phase II trial and have been taking the full 960mg dose twice a day continuously since March 2010. (My profile has information concerning tumor reduction if interested.)  As to side effects, I would have to admit that they were never debilitating but at times some were very painful; some came on very quick and I still have them and some have pretty much disappeared.

Almost immediately, I developed a rash on my entire body but never on my face and the rash is still evident today. Extreme photosensitivity also was quick to start and continues. Sunscreen, special SPF rated clothing and wide brim hats will be some of your best friends.

I’m not sure when it started, but I did have body hair loss.  I’m 65 and the hair on my head was already thinning so I do not know if Zelboraf contributed to additional head hair loss but it definitely did not all fall out although the texture did change. Today body hair has mostly returned although much thinner.

I developed many small warts on different parts of my body. Those that were sore were taken off and biopsied. One such wart turned out to be a cutaneous squamous cell carcinoma that was successfully removed with Mohs surgery.

I developed neuropathy in both feet and it was very painful for a time. I got new shoes (much wider) and today I only have mild discomfort from time to time.  There was also a period when my ankles and feet were swollen. The swelling is much better and is just a minor annoyance on my left side.

As to joint pain, there are mornings that it is difficult to get going especially up and down stairs. Similar to the head hair loss, my knees were sore prior to starting Zelboraf (arthritis?) so I am not sure of the cause.

Best of luck to you.

Dick

I have been on Zelboraf since Sept 2011

I have had severe sun reaction, 2nd degree burns, loss of all body hair, joint pain mainly in my knees,failing eyesight and

loss, of hearing, fatigue. Other than that every thin is fine. I am now only taking half dose. If I quit the tumors quickly return. I have been battling this for 17 years and am very fortunate

Tim

I have been on Zelboraf since Sept 2011

I have had severe sun reaction, 2nd degree burns, loss of all body hair, joint pain mainly in my knees,failing eyesight and

loss, of hearing, fatigue. Other than that every thin is fine. I am now only taking half dose. If I quit the tumors quickly return. I have been battling this for 17 years and am very fortunate

Tim

I have been on Zelboraf since Sept 2011

I have had severe sun reaction, 2nd degree burns, loss of all body hair, joint pain mainly in my knees,failing eyesight and

loss, of hearing, fatigue. Other than that every thin is fine. I am now only taking half dose. If I quit the tumors quickly return. I have been battling this for 17 years and am very fortunate

Tim