The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Stage 4 melanoma in a fit, sporty man – WE NEED INFORMATION!

Forums General Melanoma Community Stage 4 melanoma in a fit, sporty man – WE NEED INFORMATION!

  • Post
    Mongoose
    Participant

      My husband has stage 4 melanoma which he has been fighting for over five  years now.

      He is still doing sport and working having tried many standard treatments, numerous operations and also clinical trials. 

      We are on a phase 1 trial however the side effects are proving too challenging to manage so we need to find something else to go for. 

      The NHS dont always tell you what is available –  new drugs or even trials available in the UK or elswhere in the world so please if anyone knows what we can try – however much it costs or where it is, plesae point me in the right direction…

       

      Metastatic melanoma
      B-RAF Wild type
      N-RAS Mutant
      Lung and nodal disease
       
       
      Severe allergy to paclitaxel & trametinib
      Severe rash to ippimumilab which only worked for 5 months
      Trial phase 1 : RO5126766 (dual RAF/MEK inhibitor) 27% tumour reduction however having to be taken off it due to effects so tumours coming back.
       
       
      Thank you for taking the time to read this and hopefully find us a solution.
       
       
       
       
       
       
       
       
    Viewing 5 reply threads
    • Replies
        Gene_S
        Participant
          Hi, Since you noted anywhere in the world for a cure, the man to contact is Ralph Moss.
          He offers a consulting service for all type of cancers. Do a search on "Ralph Moss and melanoma".
           
          The following info may be of some interest, this is from the Moss Report.
           
          Germany and its neighboring countries are world leaders in non-conventional cancer treatment.  There are at least 60 CAM-oriented clinics, which treat cancer, in whole or in part, using the methods of complementary and alternative medicine (CAM).  Many of them are located in attractive spa towns.  (A spa town is indicated by the German word "Bad" (spa) in the name.)
           
          This report shall focus on clinics that are clearly "open for business" for English-speaking patients.  This leaves ten in Germany, four in Switzerland, two in Austria, and one in Denmark (not technically a German-speaking country, but strongly influenced by German practices).
           
          More info about Germany clinics can be found here.
           
           
          Here is another great place for info.
           
           
           
          He needs to have his Vitamin D3 levels checked. If you are going to fight this beast the proper range should be in the 80 to 100    25(OH)D levels.
           
          Improved Survival in Cancer Patients With High Vitamin D Levels
           
          see: 

           
          Selenium and Ubiquinol are also necessary.
           
          Best wishes,
          Gene

           

          Gene_S
          Participant
            Hi, Since you noted anywhere in the world for a cure, the man to contact is Ralph Moss.
            He offers a consulting service for all type of cancers. Do a search on "Ralph Moss and melanoma".
             
            The following info may be of some interest, this is from the Moss Report.
             
            Germany and its neighboring countries are world leaders in non-conventional cancer treatment.  There are at least 60 CAM-oriented clinics, which treat cancer, in whole or in part, using the methods of complementary and alternative medicine (CAM).  Many of them are located in attractive spa towns.  (A spa town is indicated by the German word "Bad" (spa) in the name.)
             
            This report shall focus on clinics that are clearly "open for business" for English-speaking patients.  This leaves ten in Germany, four in Switzerland, two in Austria, and one in Denmark (not technically a German-speaking country, but strongly influenced by German practices).
             
            More info about Germany clinics can be found here.
             
             
            Here is another great place for info.
             
             
             
            He needs to have his Vitamin D3 levels checked. If you are going to fight this beast the proper range should be in the 80 to 100    25(OH)D levels.
             
            Improved Survival in Cancer Patients With High Vitamin D Levels
             
            see: 

             
            Selenium and Ubiquinol are also necessary.
             
            Best wishes,
            Gene

             

              tcell
              Participant

                Hi Gene,

                thanks for posting this important information again in this thread. I remember you also pointed me to the Moss report.

                However, I checked the 2 sites in Austria where I live out (as far as I can remember it was one in Vienna, one in Carinthia or so).

                The one in Vienna seems only to be registered as a standard GP without any website which I found strange.

                Then one in Carinthia seems to have gone bankrupt 2 years ago according to a newspaper article Google found.

                I don't know how old your copy of the report is but I would really like to know how up to date they can keep their reports for all kinds of cancer as contact data is concerned.

                However, my contribution to the discussion on CAM:

                http://www.dr-kleef.at/en/home

                This is a private clinic in Vienna which has lots of patients from all over the world obviously for whom money does not matter.

                Thery offer dendritic cell therapy, hyperthermia (whole body and local), IL-2 in combination with Taurolidine which is supposed to mitigate the heavy side effects and other stuff. They also know a lot about supplements…

                I spoke to Dr. Kleef who obivously spent some time of his career at MSKCC. He seems very competent to me.

                Another cencter which I have not visited yet, also located in Vienna:
                http://www.medvital.at/index.php?idcatside=1&lang=2

                They also offer dendritic cells and different other complementary things.

                tcell
                Participant

                  Hi Gene,

                  thanks for posting this important information again in this thread. I remember you also pointed me to the Moss report.

                  However, I checked the 2 sites in Austria where I live out (as far as I can remember it was one in Vienna, one in Carinthia or so).

                  The one in Vienna seems only to be registered as a standard GP without any website which I found strange.

                  Then one in Carinthia seems to have gone bankrupt 2 years ago according to a newspaper article Google found.

                  I don't know how old your copy of the report is but I would really like to know how up to date they can keep their reports for all kinds of cancer as contact data is concerned.

                  However, my contribution to the discussion on CAM:

                  http://www.dr-kleef.at/en/home

                  This is a private clinic in Vienna which has lots of patients from all over the world obviously for whom money does not matter.

                  Thery offer dendritic cell therapy, hyperthermia (whole body and local), IL-2 in combination with Taurolidine which is supposed to mitigate the heavy side effects and other stuff. They also know a lot about supplements…

                  I spoke to Dr. Kleef who obivously spent some time of his career at MSKCC. He seems very competent to me.

                  Another cencter which I have not visited yet, also located in Vienna:
                  http://www.medvital.at/index.php?idcatside=1&lang=2

                  They also offer dendritic cells and different other complementary things.

                  Mongoose
                  Participant

                    Thank you thank you….. this is amazing info and gives us hope there is still stuff out there to try… thank you again for taking the time to reply to us.

                    Mongoose
                    Participant

                      Thank you thank you….. this is amazing info and gives us hope there is still stuff out there to try… thank you again for taking the time to reply to us.

                      Mongoose
                      Participant

                        Thank you thank you….. this is amazing info and gives us hope there is still stuff out there to try… thank you again for taking the time to reply to us.

                        tcell
                        Participant

                          Hi Gene,

                          thanks for posting this important information again in this thread. I remember you also pointed me to the Moss report.

                          However, I checked the 2 sites in Austria where I live out (as far as I can remember it was one in Vienna, one in Carinthia or so).

                          The one in Vienna seems only to be registered as a standard GP without any website which I found strange.

                          Then one in Carinthia seems to have gone bankrupt 2 years ago according to a newspaper article Google found.

                          I don't know how old your copy of the report is but I would really like to know how up to date they can keep their reports for all kinds of cancer as contact data is concerned.

                          However, my contribution to the discussion on CAM:

                          http://www.dr-kleef.at/en/home

                          This is a private clinic in Vienna which has lots of patients from all over the world obviously for whom money does not matter.

                          Thery offer dendritic cell therapy, hyperthermia (whole body and local), IL-2 in combination with Taurolidine which is supposed to mitigate the heavy side effects and other stuff. They also know a lot about supplements…

                          I spoke to Dr. Kleef who obivously spent some time of his career at MSKCC. He seems very competent to me.

                          Another cencter which I have not visited yet, also located in Vienna:
                          http://www.medvital.at/index.php?idcatside=1&lang=2

                          They also offer dendritic cells and different other complementary things.

                          Mongoose
                          Participant

                            Thank you so much for the information – I would never found this out by myself.  Will get on to it….

                            Thank you – obviously you do know how much this means to us.

                            Mongoose
                            Participant

                              Thank you so much for the information – I would never found this out by myself.  Will get on to it….

                              Thank you – obviously you do know how much this means to us.

                              Mongoose
                              Participant

                                Thank you so much for the information – I would never found this out by myself.  Will get on to it….

                                Thank you – obviously you do know how much this means to us.

                                Mongoose
                                Participant

                                  Thank you thank you thank you so much for this info – vital, invaluable and I would never have known any of it.  im sure you know how much it means so thank you for taking the time to reply.

                                  Mongoose
                                  Participant

                                    Thank you thank you thank you so much for this info – vital, invaluable and I would never have known any of it.  im sure you know how much it means so thank you for taking the time to reply.

                                    Mongoose
                                    Participant

                                      Thank you thank you thank you so much for this info – vital, invaluable and I would never have known any of it.  im sure you know how much it means so thank you for taking the time to reply.

                                    Gene_S
                                    Participant
                                      Hi, Since you noted anywhere in the world for a cure, the man to contact is Ralph Moss.
                                      He offers a consulting service for all type of cancers. Do a search on "Ralph Moss and melanoma".
                                       
                                      The following info may be of some interest, this is from the Moss Report.
                                       
                                      Germany and its neighboring countries are world leaders in non-conventional cancer treatment.  There are at least 60 CAM-oriented clinics, which treat cancer, in whole or in part, using the methods of complementary and alternative medicine (CAM).  Many of them are located in attractive spa towns.  (A spa town is indicated by the German word "Bad" (spa) in the name.)
                                       
                                      This report shall focus on clinics that are clearly "open for business" for English-speaking patients.  This leaves ten in Germany, four in Switzerland, two in Austria, and one in Denmark (not technically a German-speaking country, but strongly influenced by German practices).
                                       
                                      More info about Germany clinics can be found here.
                                       
                                       
                                      Here is another great place for info.
                                       
                                       
                                       
                                      He needs to have his Vitamin D3 levels checked. If you are going to fight this beast the proper range should be in the 80 to 100    25(OH)D levels.
                                       
                                      Improved Survival in Cancer Patients With High Vitamin D Levels
                                       
                                      see: 

                                       
                                      Selenium and Ubiquinol are also necessary.
                                       
                                      Best wishes,
                                      Gene

                                       

                                      pigs_sty
                                      Participant
                                        My wife was recently diagnosed with stage 4 and we are in the UK also, where are you receiving treatment and who by? I believe professor Ruth Plummer at the northern centre for cancer care is the best in the country especially for early phase trials. Dr Paul lorigan is based at the Christie in Manchester and is also a respected leader in this field, they also offer act there I think. Dont hesitate to contact me if I can help
                                        pigs_sty
                                        Participant
                                          My wife was recently diagnosed with stage 4 and we are in the UK also, where are you receiving treatment and who by? I believe professor Ruth Plummer at the northern centre for cancer care is the best in the country especially for early phase trials. Dr Paul lorigan is based at the Christie in Manchester and is also a respected leader in this field, they also offer act there I think. Dont hesitate to contact me if I can help
                                            Mongoose
                                            Participant

                                              We are at the Marsden in Sutton for the trials and have been at the Marsden in Fulham.  I will contact these people – thank you so much for the information as you know how much it means…. I hope your wife is OK.

                                              Mongoose
                                              Participant

                                                We are at the Marsden in Sutton for the trials and have been at the Marsden in Fulham.  I will contact these people – thank you so much for the information as you know how much it means…. I hope your wife is OK.

                                                pigs_sty
                                                Participant
                                                  No problem please let me know how you get on. If you want pm me your details I find that we the partners / carers often need support just as much as the actual patient
                                                  pigs_sty
                                                  Participant
                                                    No problem please let me know how you get on. If you want pm me your details I find that we the partners / carers often need support just as much as the actual patient
                                                    pigs_sty
                                                    Participant
                                                      Hi there do you have an update on your husbads progress? Thanks
                                                      pigs_sty
                                                      Participant
                                                        Hi there do you have an update on your husbads progress? Thanks
                                                        pigs_sty
                                                        Participant
                                                          Hi there do you have an update on your husbads progress? Thanks
                                                          pigs_sty
                                                          Participant
                                                            No problem please let me know how you get on. If you want pm me your details I find that we the partners / carers often need support just as much as the actual patient
                                                            Mongoose
                                                            Participant

                                                              We are at the Marsden in Sutton for the trials and have been at the Marsden in Fulham.  I will contact these people – thank you so much for the information as you know how much it means…. I hope your wife is OK.

                                                            pigs_sty
                                                            Participant
                                                              My wife was recently diagnosed with stage 4 and we are in the UK also, where are you receiving treatment and who by? I believe professor Ruth Plummer at the northern centre for cancer care is the best in the country especially for early phase trials. Dr Paul lorigan is based at the Christie in Manchester and is also a respected leader in this field, they also offer act there I think. Dont hesitate to contact me if I can help
                                                          Viewing 5 reply threads
                                                          • You must be logged in to reply to this topic.
                                                          About the MRF Patient Forum

                                                          The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                                                          The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

                                                          Popular Topics