› Forums › General Melanoma Community › MELANOMA CAUSING DEMENTIA
- This topic has 3 replies, 1 voice, and was last updated 10 years, 11 months ago by
joelcairo.
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- June 6, 2014 at 10:26 pm
You mentioned in another thread that the patient was suffering from cachexia. Cachexia is connected to an overwhelming level of inflammatory cytokines that are disrupting his metabolism. That might also be related to the confusion or dementia he is experiencing.
It has been demonstrated that cachexia can't be treated by merely increasing calories. My personal belief is that it could be mitigated through the use of anti-inflammatory drugs such as Indomethacin, Aspirin, Naproxen, Ibuprofen or Celebrex. Thalidomide, omega-3 oils and some flavonoids have also been proposed to be beneficial. It shouldn't be hard to find information about this online, but this will get you started.
Celebrex May Improve Cachexia in Some Patients with Cancer
http://news.cancerconnect.com/celebrex-may-improve-cachexia-in-some-patients-with-cancer/
Thalidomide in the treatment of cancer cachexia: a randomised placebo controlled trial
http://gut.bmj.com/content/54/4/540
Non-steroidal anti-inflammatory drugs for the treatment of cancer cachexia: a systematic review
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0056621/
EGCG (Green Tea Extract) effectively attenuates skeletal muscle atrophy caused by cancer cachexia
http://www.ncbi.nlm.nih.gov/pubmed/21397390
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- June 6, 2014 at 10:26 pm
You mentioned in another thread that the patient was suffering from cachexia. Cachexia is connected to an overwhelming level of inflammatory cytokines that are disrupting his metabolism. That might also be related to the confusion or dementia he is experiencing.
It has been demonstrated that cachexia can't be treated by merely increasing calories. My personal belief is that it could be mitigated through the use of anti-inflammatory drugs such as Indomethacin, Aspirin, Naproxen, Ibuprofen or Celebrex. Thalidomide, omega-3 oils and some flavonoids have also been proposed to be beneficial. It shouldn't be hard to find information about this online, but this will get you started.
Celebrex May Improve Cachexia in Some Patients with Cancer
http://news.cancerconnect.com/celebrex-may-improve-cachexia-in-some-patients-with-cancer/
Thalidomide in the treatment of cancer cachexia: a randomised placebo controlled trial
http://gut.bmj.com/content/54/4/540
Non-steroidal anti-inflammatory drugs for the treatment of cancer cachexia: a systematic review
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0056621/
EGCG (Green Tea Extract) effectively attenuates skeletal muscle atrophy caused by cancer cachexia
http://www.ncbi.nlm.nih.gov/pubmed/21397390
-
- June 6, 2014 at 10:26 pm
You mentioned in another thread that the patient was suffering from cachexia. Cachexia is connected to an overwhelming level of inflammatory cytokines that are disrupting his metabolism. That might also be related to the confusion or dementia he is experiencing.
It has been demonstrated that cachexia can't be treated by merely increasing calories. My personal belief is that it could be mitigated through the use of anti-inflammatory drugs such as Indomethacin, Aspirin, Naproxen, Ibuprofen or Celebrex. Thalidomide, omega-3 oils and some flavonoids have also been proposed to be beneficial. It shouldn't be hard to find information about this online, but this will get you started.
Celebrex May Improve Cachexia in Some Patients with Cancer
http://news.cancerconnect.com/celebrex-may-improve-cachexia-in-some-patients-with-cancer/
Thalidomide in the treatment of cancer cachexia: a randomised placebo controlled trial
http://gut.bmj.com/content/54/4/540
Non-steroidal anti-inflammatory drugs for the treatment of cancer cachexia: a systematic review
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0056621/
EGCG (Green Tea Extract) effectively attenuates skeletal muscle atrophy caused by cancer cachexia
http://www.ncbi.nlm.nih.gov/pubmed/21397390
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