MRF-Logo2019-Horizontal-RGB
4 infusions keytruda
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

4 infusions keytruda

› Forums › General Melanoma Community › 4 infusions keytruda

  • Post
    • March 11, 2019 at 1:39 am
    Godzilla
    Participant
      No change in tumors under my arm. How often does keytruda not work.
    Viewing 3 reply threads
    • Replies
        • March 11, 2019 at 2:10 am
        Bubbles
        Participant

          Anti- PD-1 products – either Keytruda (pembrolizumab) or Opdivo (nivolizumab) – have a roughly 40% response rate.  The ipi/nivo combo has a roughly 50+% response rate.  The chart included in this post notes that while responses to immunotherapy most often occur around 3 months into therapy, some may not occur until 6 – 10 months out:

          http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2016/02/time-to-responseipi-vs-nivo-and-ipi.html  

          With immunotherapy we have to remember to be "patient with the patient".  Hope this helps.  Celeste

          • March 11, 2019 at 2:30 pm
          Nympha
          Participant
            My father had also no response to keytruda treatment.. After sixth dose with no response, our onkologist switched him to taf/mek. He has many tumors on his tummy(arround scar) very painful.. We hope taf mek will help.
            • March 11, 2019 at 2:39 pm
            Nympha
            Participant
              Sometimes big tumors have big strength, and high dose radiotherapy can help imunotherapy to beat it. Try to find informations about combination of high dose radiotherapy and imunotherapy on the Internet.
              It didn’t work in our case but I saw many case when it worked.
              • March 12, 2019 at 1:23 am
              Mark_DC
              Participant

                I dont konw how bad your starting point is but no change can mean stable disease which buys time and could be a sign something is working. What does your oncologist say? In my case they gave it nine months to one year before changing course. In my case adding TVEC to keytruda helped – i think some clinical trials with this are now starting. Good luck I know staying patient is far from easy

                Mark

            Viewing 3 reply threads
            • You must be logged in to reply to this topic.
            About the MRF Patient Forum

            The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

            The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

            Popular Topics