The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

biospie report

Forums General Melanoma Community biospie report

  • Post
    Brigitte
    Participant

      I was wondering if someone could help me understand my biopsy report. 

      On top is says clinical diagnosis  Lentigo VS. MM  (does that mean what my docter dignosed and sent to the patholoogy, or what the pathologist diannosed? 

       

      under that is says: Diagnosis: Compound Nevus with dysplastic Features.

      Sections show a compound nevomelanocytic prolifeeration exhibiting dysplastic features, primarily in the form of lentiginous architectural disorder and asymmetry, accompanied by random, relatively mild, cytologic atypia. Junctional changes are focally advanced, perhaps indicative of progression, such that a conservative complete excision is recommended. 

      Im a little freaked by the words focally advanced, perhaps indicative of progression. Does that mean that maybe I do have cancer but they cannot tell until they get the excersion biobsy?    Please help me understand what all this means. 

    Viewing 2 reply threads
    • Replies
        Kim K
        Participant

          The report is saying it is difficult to distinguish from a nasty looking mole or early melanoma.  If you have to have melanoma, this is probably one of the best kind to have since it isn't blatantly screaming I am cancer.  It will come down to a judgement call by your pathologist.

          If it hasn't bee done already, make sure the slides are interpreted by a dermatopathologist.  They have special training to make those kinds of judgment calls.

          Either way, a wide excision is needed, and hopefully that will be the end of it.  You should have regular skin checks for life after this regardless.  Think of this more like a warning.  The concern is having another spot pop up rather than metastasis at this point.

            Brigitte
            Participant

               What does it mean by junctional changes are focally advanced?   The word advanced is fresking me out. 

               

               

              Janner
              Participant

                Analyzing the report line by line accomplishes nothing.  It is the sum of all the parts that makes up the final diagnosis and the doctor is justifying his diagnosis with each line.  It's the overall diagnosis that is important.  The diagnosis is NOT melanoma.  Junctional changes are related to cells located at the dermal/epidermal junction.  Everything here is "degrees".  Because there are changes at this location, it influences the diagnoses that the architecture is atypical however the cell structure only showed mild atypia. 

                Bottom line.  This isn't melanoma.  It may never have become melanoma.  But have the surgery to get the appropriate margins and move on. 

                Brigitte
                Participant

                  Thank you Janner for easing my mind and saying it in a way I understand. Last year it was the dreaded mamogram call back (which turned out to be a cyst). Waiting for results are awful and then getting back results that you have no idea if it means your still waiting or if your in the clear can play havic with your nerves. The word advance just wouldn't  get out of my head. 

                  Brigitte
                  Participant

                    Thank you Janner for easing my mind and saying it in a way I understand. Last year it was the dreaded mamogram call back (which turned out to be a cyst). Waiting for results are awful and then getting back results that you have no idea if it means your still waiting or if your in the clear can play havic with your nerves. The word advance just wouldn't  get out of my head. 

                    Brigitte
                    Participant

                      Thank you Janner for easing my mind and saying it in a way I understand. Last year it was the dreaded mamogram call back (which turned out to be a cyst). Waiting for results are awful and then getting back results that you have no idea if it means your still waiting or if your in the clear can play havic with your nerves. The word advance just wouldn't  get out of my head. 

                      Janner
                      Participant

                        Analyzing the report line by line accomplishes nothing.  It is the sum of all the parts that makes up the final diagnosis and the doctor is justifying his diagnosis with each line.  It's the overall diagnosis that is important.  The diagnosis is NOT melanoma.  Junctional changes are related to cells located at the dermal/epidermal junction.  Everything here is "degrees".  Because there are changes at this location, it influences the diagnoses that the architecture is atypical however the cell structure only showed mild atypia. 

                        Bottom line.  This isn't melanoma.  It may never have become melanoma.  But have the surgery to get the appropriate margins and move on. 

                        Janner
                        Participant

                          Analyzing the report line by line accomplishes nothing.  It is the sum of all the parts that makes up the final diagnosis and the doctor is justifying his diagnosis with each line.  It's the overall diagnosis that is important.  The diagnosis is NOT melanoma.  Junctional changes are related to cells located at the dermal/epidermal junction.  Everything here is "degrees".  Because there are changes at this location, it influences the diagnoses that the architecture is atypical however the cell structure only showed mild atypia. 

                          Bottom line.  This isn't melanoma.  It may never have become melanoma.  But have the surgery to get the appropriate margins and move on. 

                          Brigitte
                          Participant

                             What does it mean by junctional changes are focally advanced?   The word advanced is fresking me out. 

                             

                             

                            Brigitte
                            Participant

                               What does it mean by junctional changes are focally advanced?   The word advanced is fresking me out. 

                               

                               

                            Kim K
                            Participant

                              The report is saying it is difficult to distinguish from a nasty looking mole or early melanoma.  If you have to have melanoma, this is probably one of the best kind to have since it isn't blatantly screaming I am cancer.  It will come down to a judgement call by your pathologist.

                              If it hasn't bee done already, make sure the slides are interpreted by a dermatopathologist.  They have special training to make those kinds of judgment calls.

                              Either way, a wide excision is needed, and hopefully that will be the end of it.  You should have regular skin checks for life after this regardless.  Think of this more like a warning.  The concern is having another spot pop up rather than metastasis at this point.

                              Kim K
                              Participant

                                The report is saying it is difficult to distinguish from a nasty looking mole or early melanoma.  If you have to have melanoma, this is probably one of the best kind to have since it isn't blatantly screaming I am cancer.  It will come down to a judgement call by your pathologist.

                                If it hasn't bee done already, make sure the slides are interpreted by a dermatopathologist.  They have special training to make those kinds of judgment calls.

                                Either way, a wide excision is needed, and hopefully that will be the end of it.  You should have regular skin checks for life after this regardless.  Think of this more like a warning.  The concern is having another spot pop up rather than metastasis at this point.

                            Viewing 2 reply threads
                            • You must be logged in to reply to this topic.
                            About the MRF Patient Forum

                            The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                            The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

                            Popular Topics