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c-kit mutation for exon 11
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c-kit mutation for exon 11

› Forums › General Melanoma Community › c-kit mutation for exon 11

  • Post
    • November 12, 2011 at 1:59 pm
    beccia1
    Participant

      the genetic testing indicated that i have the c-kit mutation for exon 11

       

      i was wondewring what tuype of drug is prescribed for that mutation

      john b

      the genetic testing indicated that i have the c-kit mutation for exon 11

       

      i was wondewring what tuype of drug is prescribed for that mutation

      john b

    Viewing 2 reply threads
    • Replies
        • November 12, 2011 at 2:22 pm
        MichaelFL
        Participant

          Not sure there are any prescribed (don't think so anyway) but here is a trial you may wish to look at:

          http://clinicaltrials.gov/ct2/show/NCT01092728?term=c-kit+exon+11+melanoma+drugs&rank=1 

          Treatment With Dasatinib in Patients With Acral Lentiginous, Mucosal, or Chronic Sun-damaged Melanoma

          Purpose:

          The goal of this clinical research study is to compare how the drug Sprycel (dasatinib) can help to control the tumor in patients whose tumor has a gene abnormality known as a "CKIT mutation" to patients whose tumor does not have a CKIT mutation. The safety of this drug will also be studied.

          Primary Objectives

          1. To compare the biological response of tumors harboring exon 11 or 13 KIT mutations versus tumors without exon 11 or 13 KIT mutations from patients with acral, chronic sun-damaged, and mucosal melanomas after treatment with dasatinib.

           

          Good luck!

          • November 12, 2011 at 2:22 pm
          MichaelFL
          Participant

            Not sure there are any prescribed (don't think so anyway) but here is a trial you may wish to look at:

            http://clinicaltrials.gov/ct2/show/NCT01092728?term=c-kit+exon+11+melanoma+drugs&rank=1 

            Treatment With Dasatinib in Patients With Acral Lentiginous, Mucosal, or Chronic Sun-damaged Melanoma

            Purpose:

            The goal of this clinical research study is to compare how the drug Sprycel (dasatinib) can help to control the tumor in patients whose tumor has a gene abnormality known as a "CKIT mutation" to patients whose tumor does not have a CKIT mutation. The safety of this drug will also be studied.

            Primary Objectives

            1. To compare the biological response of tumors harboring exon 11 or 13 KIT mutations versus tumors without exon 11 or 13 KIT mutations from patients with acral, chronic sun-damaged, and mucosal melanomas after treatment with dasatinib.

             

            Good luck!

            • November 12, 2011 at 2:22 pm
            MichaelFL
            Participant

              Not sure there are any prescribed (don't think so anyway) but here is a trial you may wish to look at:

              http://clinicaltrials.gov/ct2/show/NCT01092728?term=c-kit+exon+11+melanoma+drugs&rank=1 

              Treatment With Dasatinib in Patients With Acral Lentiginous, Mucosal, or Chronic Sun-damaged Melanoma

              Purpose:

              The goal of this clinical research study is to compare how the drug Sprycel (dasatinib) can help to control the tumor in patients whose tumor has a gene abnormality known as a "CKIT mutation" to patients whose tumor does not have a CKIT mutation. The safety of this drug will also be studied.

              Primary Objectives

              1. To compare the biological response of tumors harboring exon 11 or 13 KIT mutations versus tumors without exon 11 or 13 KIT mutations from patients with acral, chronic sun-damaged, and mucosal melanomas after treatment with dasatinib.

               

              Good luck!

          Viewing 2 reply threads
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