Based on the details below, I feel like I am so close to getting rid of this awful disease, but there doesnt seem to be a standard of care treatment that "fits" someone in my position (particularly when considering I do not want to have any side effects that would keep me from doing a clinical trial down the line.
I've been stage 4 since July 2016, and have been on Keytruda since then. I had a surgery to prevent bone fracture and radiation of the bone early in the course of treatment.
Ive had a very fortunate response to the Keytruda since, with large tumors on the Spleen and Lungs disappearing, and no new tumors showing up. I basically have 1 bone tumor in the pelvis that is nonresponsive, and 3 small liver lesions (1.6x.9 cm, 1.1x.6 cm, <.5cm) , which, while small, are in dangerous areas as far as the damage they could do to my body if they were to grow quickly.
I also have what appears to be a lesion in the pericardial space which has grown, and is currently the reason why we may channge therapies Keytruda. Thats also an area where a single, large tumor, could be deadly.
BOTTOM LINE: Does anyone know of any trials that work well for people who have responded well (and are still responding well) to PD-1 blockade, but which does not have the toxicities associated with adding ipi or doing TIL?
Any help at all would be deeply appreciated.
.
