Duration of Treatment 12 months? vs 24?

I'm curious about this too.  I'm stage3/NED with 6 months of a 1 year clinical trial done (opdivo or opdivo/yervoy).  The trial definitely ends after 1 year or sign of progression, and – in my head – I've been thinking that immunotherapy treatment would end after the trial if I make it through the whole year, but I've never actually discussed this with my onc.  I wonder if they'd have a stage 3/resected person continue beyond one year of immunotherapy?

As in my post – due to the side effects and response I have received I have been taken off treatment for 2 reasons.  There is evidence to suggest when someone responds they don’t always need more treatment to maintain the result and if you stay on treatment and progress you have limited options.

i was only on treatment for 4 months

My wife's melanoma specialist (Dr. Hamid at Angeles Clinic) told us two years or one year past the point of NED, whichever is longer.  

So two years minimum or could got longer if NED isn't reached until sometime in the second year of treatment.

Hi Blessed, if you look at the original trial of Ipi/Nivo checkmate 067. The two arms of the trial getting Nivo continue to get treatment until progression or toxicity stopped them. Recently the trend has been going towards the data coming in from the pembro trial keynote 006, where patients were forced to stop at 2 years, and were followed to see how many of the responders stay responding. From the 103 patients that were in this sample, I believe around 85% have stayed in response at the 4 year mark, two years out from the forced stop. Some of the patients that relapsed were rechallenge do with pd-1 drug and several responded for a second time. I am not sure of the exact% but it would be in the keynote trial data or articles about the trial. I am not this best example since I haven't stopped pd-1 treatment since starting on checkmate 067 back in Jan 2014, I was a partial responder in my lung, with scans showing lung met shrinking at first then remaining the same ever since. I have heard many oncologist use NED plus 6 months as their new guidelines!!! Best Wishes!!!Ed