Effectiveness of IPI / Yervoy with Steroid Usage?
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Effectiveness of IPI / Yervoy with Steroid Usage?

› Forums › General Melanoma Community › Effectiveness of IPI / Yervoy with Steroid Usage?

  • Post
    • June 27, 2012 at 3:10 am
    Iowa98
    Participant

      Hello,

      With my father coming off of some chemo treatments, he has been using steriods to bolster his energy level.  While not the prescribed usage, it has helped with his energy and overall emotional state.  However, he is now starting IPI / Yervoy and I've read that the use of steriods may impact the effectiveness of the treatment.  Has anyone heard or experienced this?

      Thanks, what a journey……

      Jessica

      Hello,

      With my father coming off of some chemo treatments, he has been using steriods to bolster his energy level.  While not the prescribed usage, it has helped with his energy and overall emotional state.  However, he is now starting IPI / Yervoy and I've read that the use of steriods may impact the effectiveness of the treatment.  Has anyone heard or experienced this?

      Thanks, what a journey……

      Jessica

    Viewing 2 reply threads
    • Replies
        • June 27, 2012 at 7:08 am
        LynnLuc
        Participant

          I am on Anti PD1 and my derm doc wanted to put me on steroids because of a blistery rash on my hands and feet. My oncologist said NO WAY because like IPI it boosts your immune system and steroids do the complete opposite…I would have been released from the trial had I taken it.

          • June 27, 2012 at 7:08 am
          LynnLuc
          Participant

            I am on Anti PD1 and my derm doc wanted to put me on steroids because of a blistery rash on my hands and feet. My oncologist said NO WAY because like IPI it boosts your immune system and steroids do the complete opposite…I would have been released from the trial had I taken it.

            • June 27, 2012 at 7:08 am
            LynnLuc
            Participant

              I am on Anti PD1 and my derm doc wanted to put me on steroids because of a blistery rash on my hands and feet. My oncologist said NO WAY because like IPI it boosts your immune system and steroids do the complete opposite…I would have been released from the trial had I taken it.

                • June 27, 2012 at 7:14 am
                LynnLuc
                Participant

                  PS…IPI is used to boost the immune system so it can kill off the melanoma. taking the steroids lower the immune system…they do use steroids often with ipi when they have severe side effects like colitis but try to use it sparingly…I asked my onc about that…he said they hope the patient gets at least some benefit from ipi…You need to make his oncologist aware of his usage….

                  • June 27, 2012 at 7:14 am
                  LynnLuc
                  Participant

                    PS…IPI is used to boost the immune system so it can kill off the melanoma. taking the steroids lower the immune system…they do use steroids often with ipi when they have severe side effects like colitis but try to use it sparingly…I asked my onc about that…he said they hope the patient gets at least some benefit from ipi…You need to make his oncologist aware of his usage….

                    • June 27, 2012 at 7:14 am
                    LynnLuc
                    Participant

                      PS…IPI is used to boost the immune system so it can kill off the melanoma. taking the steroids lower the immune system…they do use steroids often with ipi when they have severe side effects like colitis but try to use it sparingly…I asked my onc about that…he said they hope the patient gets at least some benefit from ipi…You need to make his oncologist aware of his usage….

                      • June 29, 2012 at 12:21 am
                      NYKaren
                      Participant
                        Hi, I recently had to discontinue Yervoy due to colitis and was treated with steroids. We were tapering the steroid soI could resume Yervoy, but I was too sick from the colitis.
                        FYI, in the Yervoy literature, Yervoy is contraindicated if the patient is on more than 7.5 mg of steroids.
                        Hope this helps,
                        karen
                        • June 29, 2012 at 12:21 am
                        NYKaren
                        Participant
                          Hi, I recently had to discontinue Yervoy due to colitis and was treated with steroids. We were tapering the steroid soI could resume Yervoy, but I was too sick from the colitis.
                          FYI, in the Yervoy literature, Yervoy is contraindicated if the patient is on more than 7.5 mg of steroids.
                          Hope this helps,
                          karen
                          • June 29, 2012 at 12:21 am
                          NYKaren
                          Participant
                            Hi, I recently had to discontinue Yervoy due to colitis and was treated with steroids. We were tapering the steroid soI could resume Yervoy, but I was too sick from the colitis.
                            FYI, in the Yervoy literature, Yervoy is contraindicated if the patient is on more than 7.5 mg of steroids.
                            Hope this helps,
                            karen
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