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Failed Another Trial
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Failed Another Trial

› Forums › General Melanoma Community › Failed Another Trial

  • Post
    • November 17, 2018 at 7:08 pm
    Nick C
    Participant

      Got my scan results. There is still progression…around 10-12%…which is acceptable. It showed two spots on my spleen…first organ involvement…which was the deciding factor to end the trial. I've done Pembro. Prembro+ (Trial), Ipi, and ERK inhibtor (Trial). Since I had an issue with liver enzymes, any immunotherapy is now ruled out.

      I have been offered another clinical trial. Have to wait 2-3 weeks for an opening.  There a 3 participants in this trial at this time. So far there have not been any reported side effects. If this doesn't work…

      I feel good and living life pretty normal…looking forward to the holidays.

      Keep up the good fight! There will be something that works.

      Nick

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    • Replies
        • November 17, 2018 at 7:28 pm
        jennunicorn
        Participant

          Sending positive vibes your way for a trial that works for you Nick! This process can make it really easy to delve into the negative and make you want to give up. Having a great attitude helps push forward to the next thing. Sending hugs and wishing you a happy holiday season, despite melanoma being a stubborn you know what. 

            • November 21, 2018 at 4:21 pm
            Nick C
            Participant

              Jenn…

              Thanks for the kind words. I got word yesterday that spot openned for the new trial. Paper work and preliminaries nest week. Have a great Thanksgiving.

              Nick

            • November 17, 2018 at 8:59 pm
            AMcReader
            Participant

              Hi Nick! I really admire you’re positive attitude, I just learned Nivo alone isn’t totally doing it for me and I nearly melted down. HA!

              Anyways, I wanted to share this trial: https://blog.dana-farber.org/insight/2018/11/vaccine-implants-aim-train-immune-response-melanoma/?utm_source=twitter&utm_medium=social&utm_campaign=melanoma

              I’m going to try the Ipi/Nivo combo first but, if I wasn’t, I’d be all over this one! 

              I wish you my very best and will be rooting for you to find your answer!

              Amanda

                • November 21, 2018 at 4:24 pm
                Nick C
                Participant

                  Amanda…

                  Thank you for your support. Hoping the combo works for you. Have a great Thanksgiving.

                  Nick

                • November 18, 2018 at 2:26 pm
                Bubbles
                Participant

                  Sorry for this news, Nick.  Glad you have options!!!  You know what I always say!  Melanoma sucks great big stinky hairy green wizard balls!!!  BUT….we keep swimming!  Glad you are feeling well.  Enjoy your everyday and your holidays.  Keep us posted.  I wish you my best and hope that this trial will be exactly what you need.  Yours, celeste

                    • November 21, 2018 at 4:30 pm
                    Nick C
                    Participant

                      Celeste…

                      Thanks for your support. You are right…this sucks!! Got word yesterday that there is an openning for the new trial. I meet with them next week and hope start the first week of December. Fortunately, the trials are close to home. Have a great Thanksgiving!

                      Nick

                    • November 20, 2018 at 4:10 am
                    MelanomaMike
                    Participant

                      Brother Nick! long see no time! well, 10-12% isnt to bad in growth size, i mean, depending on "when" yer last scan was? if it was last done 2 weeks ago that would be a Terrible percentage haha..i imagine what? 2-4 months ago? slow growing is a victory. My 5.4cm Mel Monster was 2.2cm on April 24th 2018 CT scan, and as of Sept 17th 2018 its at 5.4cm! so, 5 months of fairly swift increase..I always enjoy your posts when you write, your humor has made me chuckle more then a few times brother……Anyways, Im Always behind ya brother {and im NOT Greek either, im Irish..take care..

                        • November 21, 2018 at 4:17 pm
                        Nick C
                        Participant

                          Mike…

                          Thanks, buddy. My last scan was about 6 weeks prior. We have been watching these grow for about 2 years.

                          My mother is Irish. I was told by my derm that the Irish are the worst when it comes to melanoma…Italians are the least likely to develope it…I'm both. Go figure!

                          Stay strong, my brother!

                          Nick

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