› Forums › General Melanoma Community › First week of brf113220 trial
- This topic has 6 replies, 2 voices, and was last updated 13 years, 4 months ago by
LynnLuc.
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- January 28, 2012 at 2:17 pm
Hi everyone. This is my first post. I was diagnosed stage 3c in march of 2011 with 31/35 nodes in my right neck area positive. I underwent a radical neck dissection. 6wks of radiation to the head and neck and then began my interferon infusion. I knew it would be a tough year but had no idea how bad this drug would be. I started the interferon/lexapro in august and by November my girlfriend of three yrs could not take the mood swings/lack of desire any longer. She left me and have not been able to reconcile since.Hi everyone. This is my first post. I was diagnosed stage 3c in march of 2011 with 31/35 nodes in my right neck area positive. I underwent a radical neck dissection. 6wks of radiation to the head and neck and then began my interferon infusion. I knew it would be a tough year but had no idea how bad this drug would be. I started the interferon/lexapro in august and by November my girlfriend of three yrs could not take the mood swings/lack of desire any longer. She left me and have not been able to reconcile since. A week before Christmas I got the news that there were two new metastasis on my liver seen in my early Dec. Pet scan. My oncologist decided at that time to take me off the interferon. She then prescribed me zelboraf. Before my insurance would approve it I was offered the chance to join a trial at moffitt cancer center in Tampa with Dr Jeffrey weber. The trial is for gsk’s alternative to zelboraf (braf inhibitor gsk2118436) in combo with a mek inhibitor gsk2110212. I started my meds on 1/25/12 and on my fourth day. The only problem I have had so far is dealing with the fasting twice a day for 4 hrs each time. I decided to take my pills at 10:30 so from 8:30 to 12:30 I cannot eat. Slowly deciding that this might be the best time most days. I will try to keep my side effects and result updated. This drug combo has been having great results compared to zelboraf alone including decreased side effects. We will see in the weeks and months following.
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