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How soon do side effects start after first Yervoy infusion
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How soon do side effects start after first Yervoy infusion

› Forums › General Melanoma Community › How soon do side effects start after first Yervoy infusion

  • Post
    • March 24, 2016 at 5:11 pm
    Steve Plasier
    Participant

      I am curious how soon patients noticed side effects after first infusion. I did the first one yesterday.

    Viewing 17 reply threads
    • Replies
        • March 24, 2016 at 6:02 pm
        Julie in SoCal
        Participant

          Hi Steve,

          I had few and relatively mild side effects from IPI.  Mostly headache, "general flu-like symptoms", itchy skin, joint pain and fatigue.  The headache and achy feeling hit fairly soon after treatment and went away within 4 days of so.  The joint pain, fatigue and itch took a little longer to develop, maybe 2nd or 3rd treatment.  By the 3rd and 4th treatment I developed all of them fairly quickly after the treatment.

          Hope this helps!

          Julie

          • March 24, 2016 at 6:02 pm
          Julie in SoCal
          Participant

            Hi Steve,

            I had few and relatively mild side effects from IPI.  Mostly headache, "general flu-like symptoms", itchy skin, joint pain and fatigue.  The headache and achy feeling hit fairly soon after treatment and went away within 4 days of so.  The joint pain, fatigue and itch took a little longer to develop, maybe 2nd or 3rd treatment.  By the 3rd and 4th treatment I developed all of them fairly quickly after the treatment.

            Hope this helps!

            Julie

              • March 26, 2016 at 1:56 am
              Steve Plasier
              Participant

                Today it seems like my face has been itchy off and on, but no rash. Thanks Julie for your imput.

                • March 26, 2016 at 1:56 am
                Steve Plasier
                Participant

                  Today it seems like my face has been itchy off and on, but no rash. Thanks Julie for your imput.

                  • April 1, 2016 at 5:45 pm
                  Steve Plasier
                  Participant

                    My f ace, forehead , and back have been itching since two days after first infusion. I am doing ,Benadryl and Calamine lotion which helps. I will have the second Yervoy on April 13th. 

                    • April 1, 2016 at 5:45 pm
                    Steve Plasier
                    Participant

                      My f ace, forehead , and back have been itching since two days after first infusion. I am doing ,Benadryl and Calamine lotion which helps. I will have the second Yervoy on April 13th. 

                      • April 1, 2016 at 5:45 pm
                      Steve Plasier
                      Participant

                        My f ace, forehead , and back have been itching since two days after first infusion. I am doing ,Benadryl and Calamine lotion which helps. I will have the second Yervoy on April 13th. 

                        • March 26, 2016 at 1:56 am
                        Steve Plasier
                        Participant

                          Today it seems like my face has been itchy off and on, but no rash. Thanks Julie for your imput.

                        • March 24, 2016 at 6:02 pm
                        Julie in SoCal
                        Participant

                          Hi Steve,

                          I had few and relatively mild side effects from IPI.  Mostly headache, "general flu-like symptoms", itchy skin, joint pain and fatigue.  The headache and achy feeling hit fairly soon after treatment and went away within 4 days of so.  The joint pain, fatigue and itch took a little longer to develop, maybe 2nd or 3rd treatment.  By the 3rd and 4th treatment I developed all of them fairly quickly after the treatment.

                          Hope this helps!

                          Julie

                          • March 24, 2016 at 7:44 pm
                          MoiraM
                          Participant

                            I had no side effects after the first infusion and I was told by the melanoma team that none of their patients had ever had side effects after the first infusion.

                            Diarrhoea after the second.

                            Diarrhoea and rash after the third.

                            Diarrhoea, rash and inflammation of my anterior pituary after the fourth, which was always planned to be the last. The inflammation of the pituitary was unepected because I had coped so well up to then.

                            Everything resolved but the damage to the pituitary, which is permanent.

                            Weirdly the rash and the diarrhoea came back two months after the last treatment. That bout of diarrhoea lasted 40 days!

                            • March 24, 2016 at 7:44 pm
                            MoiraM
                            Participant

                              I had no side effects after the first infusion and I was told by the melanoma team that none of their patients had ever had side effects after the first infusion.

                              Diarrhoea after the second.

                              Diarrhoea and rash after the third.

                              Diarrhoea, rash and inflammation of my anterior pituary after the fourth, which was always planned to be the last. The inflammation of the pituitary was unepected because I had coped so well up to then.

                              Everything resolved but the damage to the pituitary, which is permanent.

                              Weirdly the rash and the diarrhoea came back two months after the last treatment. That bout of diarrhoea lasted 40 days!

                                • March 26, 2016 at 1:59 am
                                Steve Plasier
                                Participant

                                  Wow 40 days is a very long time, but thanks for telling me Moira

                                  • March 26, 2016 at 1:59 am
                                  Steve Plasier
                                  Participant

                                    Wow 40 days is a very long time, but thanks for telling me Moira

                                    • March 26, 2016 at 10:57 am
                                    MoiraM
                                    Participant

                                      It was controlled with Imodium, so liveable with Looking back, taking a probiotic earlier would have been a good idea.

                                      • March 26, 2016 at 10:57 am
                                      MoiraM
                                      Participant

                                        It was controlled with Imodium, so liveable with Looking back, taking a probiotic earlier would have been a good idea.

                                        • March 26, 2016 at 10:57 am
                                        MoiraM
                                        Participant

                                          It was controlled with Imodium, so liveable with Looking back, taking a probiotic earlier would have been a good idea.

                                          • March 26, 2016 at 1:59 am
                                          Steve Plasier
                                          Participant

                                            Wow 40 days is a very long time, but thanks for telling me Moira

                                          • March 24, 2016 at 7:44 pm
                                          MoiraM
                                          Participant

                                            I had no side effects after the first infusion and I was told by the melanoma team that none of their patients had ever had side effects after the first infusion.

                                            Diarrhoea after the second.

                                            Diarrhoea and rash after the third.

                                            Diarrhoea, rash and inflammation of my anterior pituary after the fourth, which was always planned to be the last. The inflammation of the pituitary was unepected because I had coped so well up to then.

                                            Everything resolved but the damage to the pituitary, which is permanent.

                                            Weirdly the rash and the diarrhoea came back two months after the last treatment. That bout of diarrhoea lasted 40 days!

                                            • March 24, 2016 at 10:46 pm
                                            jennunicorn
                                            Participant

                                              After the first infusion I noticed the fatigue set in the next day and that lasted about a week or so after the infusion. Every infusion has given me fatigue, I didn't experience many side effects. I have had some mild itchiness after the 3rd and 4th one. Few headaches here and there after infusions but I get headaches easily anyway so it was hard to tell if it was related. Joint pain started after the 3rd one, but for me joint pain is nothing new, so again it's hard to tell if it was Ipi related. 

                                              Hope it goes smoothly for you.

                                              • March 24, 2016 at 10:46 pm
                                              jennunicorn
                                              Participant

                                                After the first infusion I noticed the fatigue set in the next day and that lasted about a week or so after the infusion. Every infusion has given me fatigue, I didn't experience many side effects. I have had some mild itchiness after the 3rd and 4th one. Few headaches here and there after infusions but I get headaches easily anyway so it was hard to tell if it was related. Joint pain started after the 3rd one, but for me joint pain is nothing new, so again it's hard to tell if it was Ipi related. 

                                                Hope it goes smoothly for you.

                                                  • March 26, 2016 at 2:04 am
                                                  Steve Plasier
                                                  Participant

                                                    Thanks Jenn, I have fatigue all the time from other meds and the Multiple Myeloma. Some of the side effects will be hard for me to say its from Yervoy.

                                                    • March 26, 2016 at 2:04 am
                                                    Steve Plasier
                                                    Participant

                                                      Thanks Jenn, I have fatigue all the time from other meds and the Multiple Myeloma. Some of the side effects will be hard for me to say its from Yervoy.

                                                      • March 26, 2016 at 2:04 am
                                                      Steve Plasier
                                                      Participant

                                                        Thanks Jenn, I have fatigue all the time from other meds and the Multiple Myeloma. Some of the side effects will be hard for me to say its from Yervoy.

                                                      • March 24, 2016 at 10:46 pm
                                                      jennunicorn
                                                      Participant

                                                        After the first infusion I noticed the fatigue set in the next day and that lasted about a week or so after the infusion. Every infusion has given me fatigue, I didn't experience many side effects. I have had some mild itchiness after the 3rd and 4th one. Few headaches here and there after infusions but I get headaches easily anyway so it was hard to tell if it was related. Joint pain started after the 3rd one, but for me joint pain is nothing new, so again it's hard to tell if it was Ipi related. 

                                                        Hope it goes smoothly for you.

                                                        • March 25, 2016 at 12:48 pm
                                                        JuTMSY4
                                                        Participant

                                                          Hi Steve – essentially no side effects for the course.  Maybe a little fatigue, but it's hard to say if that wasn't just in my head.  I later developed itchy/dry hands and feet, but it could also be attributed to Keytruda.

                                                          One thing Ipi did do for me was reduce my bone met pain drastically.  Lesion were still there, but the pain was gone.  I started my treatment back when Ipi was frontline stage 4 treatment and Keytruda was second, so I did Ipi then Keytruda.  
                                                           

                                                          Good luck – Justin

                                                          • March 25, 2016 at 12:48 pm
                                                          JuTMSY4
                                                          Participant

                                                            Hi Steve – essentially no side effects for the course.  Maybe a little fatigue, but it's hard to say if that wasn't just in my head.  I later developed itchy/dry hands and feet, but it could also be attributed to Keytruda.

                                                            One thing Ipi did do for me was reduce my bone met pain drastically.  Lesion were still there, but the pain was gone.  I started my treatment back when Ipi was frontline stage 4 treatment and Keytruda was second, so I did Ipi then Keytruda.  
                                                             

                                                            Good luck – Justin

                                                              • March 26, 2016 at 2:09 am
                                                              Steve Plasier
                                                              Participant

                                                                Thanks Justin,  6 years ago my side effects from chemo were mild, so maybe I will be lucky with Yervoy.

                                                                • March 26, 2016 at 2:09 am
                                                                Steve Plasier
                                                                Participant

                                                                  Thanks Justin,  6 years ago my side effects from chemo were mild, so maybe I will be lucky with Yervoy.

                                                                  • March 26, 2016 at 2:09 am
                                                                  Steve Plasier
                                                                  Participant

                                                                    Thanks Justin,  6 years ago my side effects from chemo were mild, so maybe I will be lucky with Yervoy.

                                                                  • March 25, 2016 at 12:48 pm
                                                                  JuTMSY4
                                                                  Participant

                                                                    Hi Steve – essentially no side effects for the course.  Maybe a little fatigue, but it's hard to say if that wasn't just in my head.  I later developed itchy/dry hands and feet, but it could also be attributed to Keytruda.

                                                                    One thing Ipi did do for me was reduce my bone met pain drastically.  Lesion were still there, but the pain was gone.  I started my treatment back when Ipi was frontline stage 4 treatment and Keytruda was second, so I did Ipi then Keytruda.  
                                                                     

                                                                    Good luck – Justin

                                                                    • March 25, 2016 at 12:50 pm
                                                                    JuTMSY4
                                                                    Participant

                                                                      Hi Steve – essentially no side effects for the course.  Maybe a little fatigue, but it's hard to say if that wasn't just in my head.  I later developed itchy/dry hands and feet, but it could also be attributed to Keytruda.

                                                                      One thing Ipi did do for me was reduce my bone met pain drastically.  Lesion were still there, but the pain was gone.  I started my treatment back when Ipi was frontline stage 4 treatment and Keytruda was second, so I did Ipi then Keytruda.  
                                                                       

                                                                      Good luck – Justin

                                                                      • March 25, 2016 at 12:50 pm
                                                                      JuTMSY4
                                                                      Participant

                                                                        Hi Steve – essentially no side effects for the course.  Maybe a little fatigue, but it's hard to say if that wasn't just in my head.  I later developed itchy/dry hands and feet, but it could also be attributed to Keytruda.

                                                                        One thing Ipi did do for me was reduce my bone met pain drastically.  Lesion were still there, but the pain was gone.  I started my treatment back when Ipi was frontline stage 4 treatment and Keytruda was second, so I did Ipi then Keytruda.  
                                                                         

                                                                        Good luck – Justin

                                                                        • March 25, 2016 at 12:50 pm
                                                                        JuTMSY4
                                                                        Participant

                                                                          Hi Steve – essentially no side effects for the course.  Maybe a little fatigue, but it's hard to say if that wasn't just in my head.  I later developed itchy/dry hands and feet, but it could also be attributed to Keytruda.

                                                                          One thing Ipi did do for me was reduce my bone met pain drastically.  Lesion were still there, but the pain was gone.  I started my treatment back when Ipi was frontline stage 4 treatment and Keytruda was second, so I did Ipi then Keytruda.  
                                                                           

                                                                          Good luck – Justin

                                                                          • March 26, 2016 at 2:22 pm
                                                                          Scooby123
                                                                          Participant

                                                                            Hi Steve,

                                                                            i had itchy skin on second dose and bowel issues on third , everyone is different in how they respond to treatment. I hope you get through it ok.

                                                                            take care

                                                                            scooby123❤️

                                                                            • March 26, 2016 at 2:22 pm
                                                                            Scooby123
                                                                            Participant

                                                                              Hi Steve,

                                                                              i had itchy skin on second dose and bowel issues on third , everyone is different in how they respond to treatment. I hope you get through it ok.

                                                                              take care

                                                                              scooby123❤️

                                                                              • March 26, 2016 at 2:22 pm
                                                                              Scooby123
                                                                              Participant

                                                                                Hi Steve,

                                                                                i had itchy skin on second dose and bowel issues on third , everyone is different in how they respond to treatment. I hope you get through it ok.

                                                                                take care

                                                                                scooby123❤️

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