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ipi nivo combo after keytruda

This topic has 3 replies, 2 voices, and was last updated 8 years ago by zfishberg.

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- April 27, 2017 at 11:42 pm
- Quote
zfishberg
Participant
Hello!

i wanted to check whether anybody tried the combo treatment after several Keytruda infusions.

My husband had 3 infusions and 2 Gamma Knife treatments.

His last Two MRI tests showed progression – significant enlargement of majority of existing lesions and multiple new lesions.

The conclusion was that Keytruda is not working and the plan is to start on the combo following Opdivo as a single agent.

Are there any concerns regarding efficacy of the combo after Keytruda?

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- - April 29, 2017 at 11:22 am
  - Quote
  Bubbles
  Participant
  Here are some reports that shed at least some light on your question:
  
  http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2017/02/response-to-ipi-or-ipinivo-after.html
  
  more below….
  - April 29, 2017 at 11:24 am
    
    Quote
    Bubbles
    Participant
    
    And, there are these….though they are more about ipi as a single agent after anti-PD-1:
    
    http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2016/05/response-to-ipi-after-being-treated.html
    
    http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/05/asco-2015-nivo-and-pembro-after-failing.
    
    For what it's worth. I wish you and your husband well. Celeste
  - April 29, 2017 at 1:44 pm
    
    Quote
    zfishberg
    Participant
    
    Thank you both for the info and support.
    
    although we are starting to loose hope, my husband is a real fighter . He tries to walk every day for 2-3 miles and willing to try everything possible.
    
    will keep posting

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ipi nivo combo after keytruda

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