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Ipi questions
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Ipi questions

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  • Post
    • December 5, 2012 at 7:30 am
    melmar
    Participant

      I have not posted in a while as it has been a tumultuous couple of months.  In September, I learned I was no longer responding to anti-pd1 with growth in spots in lung and back and a new one in adrenal gland.  Started ipi two weeks later.  Have had terrible side effects — fatique, itching, gastro, muscle aches and today learned that ALT and AST levels are greater than 5x upper limit.  So i have started 80mg of prednisone and am not allowed 4th infusion.  Feeling amazingly better after two doses of prednisone but worried about not receiving final dose of ipi.

      I have not posted in a while as it has been a tumultuous couple of months.  In September, I learned I was no longer responding to anti-pd1 with growth in spots in lung and back and a new one in adrenal gland.  Started ipi two weeks later.  Have had terrible side effects — fatique, itching, gastro, muscle aches and today learned that ALT and AST levels are greater than 5x upper limit.  So i have started 80mg of prednisone and am not allowed 4th infusion.  Feeling amazingly better after two doses of prednisone but worried about not receiving final dose of ipi.  Anyone out there achieving complete or partial response even without receiving all four doses?  Keeping the faith, but would love to read some success stories.  

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    • Replies
        • December 5, 2012 at 3:44 pm
        jim Breitfeller
        Participant

          Yes, I had only one dose Ipi at 15mg/kg. It was followed up with HD IL-2  (3 rounds) NED = 5 yrs now.

          You might want to look into HD IL-2 therapy if your body can handle it.

           

          Best regards

           

          Jimmy b

          • December 5, 2012 at 3:44 pm
          jim Breitfeller
          Participant

            Yes, I had only one dose Ipi at 15mg/kg. It was followed up with HD IL-2  (3 rounds) NED = 5 yrs now.

            You might want to look into HD IL-2 therapy if your body can handle it.

             

            Best regards

             

            Jimmy b

              • December 5, 2012 at 3:57 pm
              melmar
              Participant

                Thanks for the reply and your earlier email.  It has been such a whirlwind I haven't had time to reply.  Thanks again…I am considering this as a next option.

                • December 5, 2012 at 3:57 pm
                melmar
                Participant

                  Thanks for the reply and your earlier email.  It has been such a whirlwind I haven't had time to reply.  Thanks again…I am considering this as a next option.

                  • December 5, 2012 at 3:57 pm
                  melmar
                  Participant

                    Thanks for the reply and your earlier email.  It has been such a whirlwind I haven't had time to reply.  Thanks again…I am considering this as a next option.

                    • December 5, 2012 at 3:59 pm
                    melmar
                    Participant

                      Thanks for the reply and your earlier email. It has been such a whirlwind I haven't had time to reply. Thanks again…I am considering this as a next option.

                      • December 5, 2012 at 3:59 pm
                      melmar
                      Participant

                        Thanks for the reply and your earlier email. It has been such a whirlwind I haven't had time to reply. Thanks again…I am considering this as a next option.

                        • December 5, 2012 at 3:59 pm
                        melmar
                        Participant

                          Thanks for the reply and your earlier email. It has been such a whirlwind I haven't had time to reply. Thanks again…I am considering this as a next option.

                        • December 5, 2012 at 3:44 pm
                        jim Breitfeller
                        Participant

                          Yes, I had only one dose Ipi at 15mg/kg. It was followed up with HD IL-2  (3 rounds) NED = 5 yrs now.

                          You might want to look into HD IL-2 therapy if your body can handle it.

                           

                          Best regards

                           

                          Jimmy b

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