› Forums › General Melanoma Community › Ippi (Yervoy) reinduction?
- This topic has 9 replies, 2 voices, and was last updated 12 years, 2 months ago by
Erinmay22.
- Post
-
- March 7, 2013 at 12:49 am
Hi everyone,
Hi everyone,
It has been some time since I last posted although I have been reading the posts to keep up with everyone. My dad's last treatment with Yervoy was in November 2011 and he had a bad reaction after his last dose. He was hospitalized for about a week for low sodium and he lost control of his speech and movements. The oncologist said it was a reaction from Yervoy that caused swelling in his brain and he was treated with steriods. In April/May 2012 he also had radiation on an area of his leg to control the bleeding from the lesions and it did stop the bleeding. His oncologist think he had a partial response to Yervoy in slowing down the cancer and some (not all) of his lesions flattened although they didn't go away. A couple of months ago, he noticed two hard golf-ball sized lumps in his groin area. His oncologist wants to do a pet scan and said we can either do a second round of Yervoy, chemo, or do nothing. He doesnt have any symptoms of the disease progressing and his bloodwork seems to be normal. Do the lumps means that his cancer has spread the lymph nodes in that area?
I know some of you have done Yervoy reinduction and was wondering whether it worked for you. Also were the side effects the same, different or worse than the first time you did Yervoy. I can't remember reading anything on how effective a reinduction of Yervoy is, especially for partial responders. Also, I am concerned that dad may not be able to tolerate it since he had such bad reaction last time. Please let me know any suggestions or advice.
Thank you everyone,
Chau
- Replies
-
-
- March 7, 2013 at 2:55 am
Sorry to hear about what your dad is going thru. Is it possible for him to get in an anti-pd1 trial? I finished ipi end of November. Had growth in my lymph node and started pd1 trial at Sloan end of January.Erin
-
- March 7, 2013 at 3:21 pm
Hi Erin,
We will ask his oncologist again about anti-pd1 but I am afraid his age and health may disqualify him. I have read that anti-pd1 side effects are more tolerable than yervoy, how have they been for you and especially compared with ipi? When do you get scans?
Wish you all the best and I hope the anti-pd1 will work for you.
Chau
-
- March 7, 2013 at 5:24 pm
Hey Chau –
I can look at the paperwork when I get home about exclusions – but yes side effects much less. But I didn't really get any on ipi either. I get itchy skin that's been about it. Just finished 3rd dose on Monday. Have scans April 12th with results on the 15th.
Best of luck!
Erin
-
- March 7, 2013 at 5:24 pm
Hey Chau –
I can look at the paperwork when I get home about exclusions – but yes side effects much less. But I didn't really get any on ipi either. I get itchy skin that's been about it. Just finished 3rd dose on Monday. Have scans April 12th with results on the 15th.
Best of luck!
Erin
-
- March 7, 2013 at 5:24 pm
Hey Chau –
I can look at the paperwork when I get home about exclusions – but yes side effects much less. But I didn't really get any on ipi either. I get itchy skin that's been about it. Just finished 3rd dose on Monday. Have scans April 12th with results on the 15th.
Best of luck!
Erin
-
- March 7, 2013 at 3:21 pm
Hi Erin,
We will ask his oncologist again about anti-pd1 but I am afraid his age and health may disqualify him. I have read that anti-pd1 side effects are more tolerable than yervoy, how have they been for you and especially compared with ipi? When do you get scans?
Wish you all the best and I hope the anti-pd1 will work for you.
Chau
-
- March 7, 2013 at 3:21 pm
Hi Erin,
We will ask his oncologist again about anti-pd1 but I am afraid his age and health may disqualify him. I have read that anti-pd1 side effects are more tolerable than yervoy, how have they been for you and especially compared with ipi? When do you get scans?
Wish you all the best and I hope the anti-pd1 will work for you.
Chau
- You must be logged in to reply to this topic.