The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

is anyone taking keytruda, if so, what about the side effects

Forums General Melanoma Community is anyone taking keytruda, if so, what about the side effects

  • Post
Viewing 11 reply threads
  • Replies
      JuTMSY4
      Participant

        Yes.  

        Initial side effects were a mild tiredness after the infusion (might just be from the long day at my oncologist's office).  

        I have always had dry skin, mostly on my fingers (dry, cracked, red) and Pembro seems to exacerbate it.  After about 8-9 infusions (during which I was stable, with potential mild growth or inflamation – Docs couldn't say) my whole hands, bottoms of my feet and a few other patches all began getting very dry.  It was as if the dryness from my fingers had spread.  Right now, my hands (the bottoms) and some of my feet are dry, itchy and cracked.  I wear gloves at night to cope and moisturizing very often.  It's not that terrible though.

        During my last scan, this time a PET (previous scans from starting Pembro were all Bone/CT), they did not find any metabolic activity suggesting cancer.

        I have not experienced colitis, liver inflammation or other major side effects and am frequently listed as "tolerating very well."  

        JuTMSY4
        Participant

          Yes.  

          Initial side effects were a mild tiredness after the infusion (might just be from the long day at my oncologist's office).  

          I have always had dry skin, mostly on my fingers (dry, cracked, red) and Pembro seems to exacerbate it.  After about 8-9 infusions (during which I was stable, with potential mild growth or inflamation – Docs couldn't say) my whole hands, bottoms of my feet and a few other patches all began getting very dry.  It was as if the dryness from my fingers had spread.  Right now, my hands (the bottoms) and some of my feet are dry, itchy and cracked.  I wear gloves at night to cope and moisturizing very often.  It's not that terrible though.

          During my last scan, this time a PET (previous scans from starting Pembro were all Bone/CT), they did not find any metabolic activity suggesting cancer.

          I have not experienced colitis, liver inflammation or other major side effects and am frequently listed as "tolerating very well."  

          JuTMSY4
          Participant

            Yes.  

            Initial side effects were a mild tiredness after the infusion (might just be from the long day at my oncologist's office).  

            I have always had dry skin, mostly on my fingers (dry, cracked, red) and Pembro seems to exacerbate it.  After about 8-9 infusions (during which I was stable, with potential mild growth or inflamation – Docs couldn't say) my whole hands, bottoms of my feet and a few other patches all began getting very dry.  It was as if the dryness from my fingers had spread.  Right now, my hands (the bottoms) and some of my feet are dry, itchy and cracked.  I wear gloves at night to cope and moisturizing very often.  It's not that terrible though.

            During my last scan, this time a PET (previous scans from starting Pembro were all Bone/CT), they did not find any metabolic activity suggesting cancer.

            I have not experienced colitis, liver inflammation or other major side effects and am frequently listed as "tolerating very well."  

              bessiesue
              Participant

                Thank you so much, very helpful information. My husband is stage 3c, melanoma found in 2014 that had mets to the sential nodes in the groin, they removed them. He had a CT scan in Oct that showed 4 densitys in his thigh. 3 positive biopsys. They are going to repeat the Scan next month and are talking about using keytruda. I hope that you are doing well, and continue to do so.

                bessiesue
                Participant

                  Thank you so much, very helpful information. My husband is stage 3c, melanoma found in 2014 that had mets to the sential nodes in the groin, they removed them. He had a CT scan in Oct that showed 4 densitys in his thigh. 3 positive biopsys. They are going to repeat the Scan next month and are talking about using keytruda. I hope that you are doing well, and continue to do so.

                  bessiesue
                  Participant

                    Thank you so much, very helpful information. My husband is stage 3c, melanoma found in 2014 that had mets to the sential nodes in the groin, they removed them. He had a CT scan in Oct that showed 4 densitys in his thigh. 3 positive biopsys. They are going to repeat the Scan next month and are talking about using keytruda. I hope that you are doing well, and continue to do so.

                  AllysonRuth
                  Participant

                    I have been taking Keytruda since October.  I have had very few side effects.  I have been sick and fatigued, but the doctors are attributing that more to pneumonia and a collapsed lung, rather than the Keytruda.  After treatment number three my skin itched for about a week and then it just stopped.  Been relatively easy drug to be on.   I should find out today if the drug is working after getting recent scans…hopefully yes! 

                    Good luck!

                    Stage IV with brain, lung and small intestine mets

                    AllysonRuth
                    Participant

                      I have been taking Keytruda since October.  I have had very few side effects.  I have been sick and fatigued, but the doctors are attributing that more to pneumonia and a collapsed lung, rather than the Keytruda.  After treatment number three my skin itched for about a week and then it just stopped.  Been relatively easy drug to be on.   I should find out today if the drug is working after getting recent scans…hopefully yes! 

                      Good luck!

                      Stage IV with brain, lung and small intestine mets

                      AllysonRuth
                      Participant

                        I have been taking Keytruda since October.  I have had very few side effects.  I have been sick and fatigued, but the doctors are attributing that more to pneumonia and a collapsed lung, rather than the Keytruda.  After treatment number three my skin itched for about a week and then it just stopped.  Been relatively easy drug to be on.   I should find out today if the drug is working after getting recent scans…hopefully yes! 

                        Good luck!

                        Stage IV with brain, lung and small intestine mets

                          bessiesue
                          Participant

                            Thank you for your reply, wish you the best

                            bessiesue
                            Participant

                              Thank you for your reply, wish you the best

                              bessiesue
                              Participant

                                Thank you for your reply, wish you the best

                              mrsaxde
                              Participant

                                I have been on Keytruda since July, and have had something like 9 infusions now I think…I lost count.

                                The side effects I have experienced have been so mild they are hardly noticeable. Some fatigue that comes and goes without warning, but which isn't debilitating at all. Usually a short nap helps a lot. A little joint pain, mainly in my knees, and my feet and ankles sometimes hurt when I get up in the morning.

                                Dry skin, and a very mild, itchy rash that is nowhere near as bad as what I got with ipi. I was on prednisone for several months because of that, and with Keytruda the itching is so mild that I haven't had to take steroids at all.

                                No stomach or gastric issues at all. Right now I'm having no ill effects from the cancer, and no ill effects from the treatment. If it wasn't for this medi-port on my chest, I wouldn't even know I was sick!

                                -Bill

                                mrsaxde
                                Participant

                                  I have been on Keytruda since July, and have had something like 9 infusions now I think…I lost count.

                                  The side effects I have experienced have been so mild they are hardly noticeable. Some fatigue that comes and goes without warning, but which isn't debilitating at all. Usually a short nap helps a lot. A little joint pain, mainly in my knees, and my feet and ankles sometimes hurt when I get up in the morning.

                                  Dry skin, and a very mild, itchy rash that is nowhere near as bad as what I got with ipi. I was on prednisone for several months because of that, and with Keytruda the itching is so mild that I haven't had to take steroids at all.

                                  No stomach or gastric issues at all. Right now I'm having no ill effects from the cancer, and no ill effects from the treatment. If it wasn't for this medi-port on my chest, I wouldn't even know I was sick!

                                  -Bill

                                  mrsaxde
                                  Participant

                                    I have been on Keytruda since July, and have had something like 9 infusions now I think…I lost count.

                                    The side effects I have experienced have been so mild they are hardly noticeable. Some fatigue that comes and goes without warning, but which isn't debilitating at all. Usually a short nap helps a lot. A little joint pain, mainly in my knees, and my feet and ankles sometimes hurt when I get up in the morning.

                                    Dry skin, and a very mild, itchy rash that is nowhere near as bad as what I got with ipi. I was on prednisone for several months because of that, and with Keytruda the itching is so mild that I haven't had to take steroids at all.

                                    No stomach or gastric issues at all. Right now I'm having no ill effects from the cancer, and no ill effects from the treatment. If it wasn't for this medi-port on my chest, I wouldn't even know I was sick!

                                    -Bill

                                    katieherwig
                                    Participant

                                      I will have my 18th dose on the 20th. Side effects for me have been mild. Some colitis and dermitis but all tolerable. I do have fatigue that's irregular. But that could be from being a mom too! I wish you all the best!

                                      katieherwig
                                      Participant

                                        I will have my 18th dose on the 20th. Side effects for me have been mild. Some colitis and dermitis but all tolerable. I do have fatigue that's irregular. But that could be from being a mom too! I wish you all the best!

                                        katieherwig
                                        Participant

                                          I will have my 18th dose on the 20th. Side effects for me have been mild. Some colitis and dermitis but all tolerable. I do have fatigue that's irregular. But that could be from being a mom too! I wish you all the best!

                                      Viewing 11 reply threads
                                      • You must be logged in to reply to this topic.
                                      About the MRF Patient Forum

                                      The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                                      The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.