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Is tooth decay an adverse effect of immunotherap?
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Is tooth decay an adverse effect of immunotherap?

› Forums › General Melanoma Community › Is tooth decay an adverse effect of immunotherap?

  • Post
    • July 3, 2016 at 8:57 pm
    Want2help
    Participant

      Does anyone know if tooth decay (dental caries) is a known adverse effect of immunotherapy, specifically Keytruda and/or Ipi?

      Thank you!

    Viewing 5 reply threads
    • Replies
        • July 4, 2016 at 12:55 am
        Casitas1
        Participant

          I have had 0 cavities on IPI/NIVO, low dose chemo and now Keytruda.

          Best, Paul

          • July 4, 2016 at 12:55 am
          Casitas1
          Participant

            I have had 0 cavities on IPI/NIVO, low dose chemo and now Keytruda.

            Best, Paul

              • July 4, 2016 at 1:14 pm
              Maureen038
              Participant

                My husband was on the Ipi/Nivo trial and was taken off a year and half ago and since then he has dealt with dry mouth. He has had two cavities since the trial. His dentist says the lack of salvia can do that. He uses biotin, sugarless candies and a special toothpaste from the dentist called Clinpro5000. Food tastes different to him now too. He refers to food as dry or moist and always prefers moist food so sauces and condiments are very important to him. Good luck!

                Maureen

                • July 4, 2016 at 1:14 pm
                Maureen038
                Participant

                  My husband was on the Ipi/Nivo trial and was taken off a year and half ago and since then he has dealt with dry mouth. He has had two cavities since the trial. His dentist says the lack of salvia can do that. He uses biotin, sugarless candies and a special toothpaste from the dentist called Clinpro5000. Food tastes different to him now too. He refers to food as dry or moist and always prefers moist food so sauces and condiments are very important to him. Good luck!

                  Maureen

                  • July 4, 2016 at 1:14 pm
                  Maureen038
                  Participant

                    My husband was on the Ipi/Nivo trial and was taken off a year and half ago and since then he has dealt with dry mouth. He has had two cavities since the trial. His dentist says the lack of salvia can do that. He uses biotin, sugarless candies and a special toothpaste from the dentist called Clinpro5000. Food tastes different to him now too. He refers to food as dry or moist and always prefers moist food so sauces and condiments are very important to him. Good luck!

                    Maureen

                  • July 4, 2016 at 12:55 am
                  Casitas1
                  Participant

                    I have had 0 cavities on IPI/NIVO, low dose chemo and now Keytruda.

                    Best, Paul

                    • July 4, 2016 at 6:06 pm
                    MoiraM
                    Participant

                      I did have a dip in the condiition of my teeth. However, goodness knows if it is directly or indirectly a side effect of the Ipi I was treated with.

                      Ipi and Keytruda stimulate the immune system, which means that many of the side effects are due to unanticipated autoimmune effects.

                      In my case that is a permanently damaged anterior pituitary gland, My body now feels and functions very differently, Is symptom B (of A through E) a direct side effect of the Ipi? Is it a secondary side effect of the lack of pituitary gland function, which means that lots of my other glands don't work either?

                      I did have low vitamin D levels. Again, tracking down the cause is probably beyond me or my doctors.That could have meant a calcium deficiency that could have last 3 months (the time between blood tests).

                      Or maybe I was just less careful with my dental hygiene while riding the rollercoaster of melanoma!

                      • July 4, 2016 at 6:06 pm
                      MoiraM
                      Participant

                        I did have a dip in the condiition of my teeth. However, goodness knows if it is directly or indirectly a side effect of the Ipi I was treated with.

                        Ipi and Keytruda stimulate the immune system, which means that many of the side effects are due to unanticipated autoimmune effects.

                        In my case that is a permanently damaged anterior pituitary gland, My body now feels and functions very differently, Is symptom B (of A through E) a direct side effect of the Ipi? Is it a secondary side effect of the lack of pituitary gland function, which means that lots of my other glands don't work either?

                        I did have low vitamin D levels. Again, tracking down the cause is probably beyond me or my doctors.That could have meant a calcium deficiency that could have last 3 months (the time between blood tests).

                        Or maybe I was just less careful with my dental hygiene while riding the rollercoaster of melanoma!

                          • July 5, 2016 at 2:22 pm
                          phancaopatrick001
                          Participant

                            At the Asset Protection & Elder Law Center, we are committed to representing our clients with integrity, hard work, and highly personal legal counsel. We strive to make sure you understand your options by explaining complex legal matters in real English, not “Legalese.”

                            • July 5, 2016 at 2:22 pm
                            phancaopatrick001
                            Participant

                              At the Asset Protection & Elder Law Center, we are committed to representing our clients with integrity, hard work, and highly personal legal counsel. We strive to make sure you understand your options by explaining complex legal matters in real English, not “Legalese.”

                              • July 5, 2016 at 2:22 pm
                              phancaopatrick001
                              Participant

                                At the Asset Protection & Elder Law Center, we are committed to representing our clients with integrity, hard work, and highly personal legal counsel. We strive to make sure you understand your options by explaining complex legal matters in real English, not “Legalese.”

                              • July 4, 2016 at 6:06 pm
                              MoiraM
                              Participant

                                I did have a dip in the condiition of my teeth. However, goodness knows if it is directly or indirectly a side effect of the Ipi I was treated with.

                                Ipi and Keytruda stimulate the immune system, which means that many of the side effects are due to unanticipated autoimmune effects.

                                In my case that is a permanently damaged anterior pituitary gland, My body now feels and functions very differently, Is symptom B (of A through E) a direct side effect of the Ipi? Is it a secondary side effect of the lack of pituitary gland function, which means that lots of my other glands don't work either?

                                I did have low vitamin D levels. Again, tracking down the cause is probably beyond me or my doctors.That could have meant a calcium deficiency that could have last 3 months (the time between blood tests).

                                Or maybe I was just less careful with my dental hygiene while riding the rollercoaster of melanoma!

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