MRF-Logo2019-Horizontal-RGB
Keydruda side effects
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Keydruda side effects

› Forums › General Melanoma Community › Keydruda side effects

  • Post
    • August 27, 2017 at 4:27 pm
    Scooby123
    Participant

      Hi all hope you all are good as can be expected. Please can who has had or on keydruda give me there experience with side effects. When started and what. I have only had 1 dose not much side effects apart from little upset stomach and strange pins and needle feeling in arms and hands on and off. I am off for second dose Tuesday coming. The consultant said it can interfere with the nerves.

       

      Scooby❤️

    Viewing 6 reply threads
    • Replies
        • August 27, 2017 at 7:04 pm
        Jahendry12
        Participant

          Hello Scooby – my husband was on keytruda for about 5 months last year. He got a rash on his arms, chest & legs and then vitiligo. He started getting some mild colitis toward the 5th month so he was taken off as the tumor resolved itself.  Not bad side effects at all. If I remember correctly, he did not suffer any fatigue, nerve issues or vomiting. 

          Hope this helps. Wishing you much success with this treatment. It has done much for so many. 

           

          Julie. 

            • August 27, 2017 at 8:44 pm
            Scooby123
            Participant
              Thanks Julie, hope all is well.2nd dose this Tuesday hoping to be a responder.
              • August 28, 2017 at 12:48 am
              LHiner50
              Participant

                Hi Scooby  I had the same side effects as Julie's husband – Severe rash and viitiligo.  I only had three Keytruda treatments but the rash began immediately.  Prednisone took care of that.  Five months later I started with vitiligo.  My last two scans have been stable.  No other side effects for me.  I was on Ipi/nivo

                previously and had to stop because of pancreas and thyroid issues that were resolved with meds

                Good luck with treatment

                 

                • August 28, 2017 at 6:18 am
                Scooby123
                Participant

                  Thank you , hope you ok and doing well.

                • August 28, 2017 at 2:47 am
                Kristi A.
                Participant

                  Hi Scooby. I was on Keytruda for a total of 8 infusions. I'm no longer on it due to side effects and scans showing Ned. At first I was a little fatigued starting after the 1st infusion. Also had some nausea but nothing too bad. Then after about the third dose I developed joint pain. After the 5th dose I was in so much pain in my joints that we stopped keytruda and had me see a rheumatologist.  Found out I developed inflammatory arthritis from the Keytruda so i was put on prednisone and plaquenil.  Stayed on both meds and restarted keytruda a month and a half later. Did three more doses and stopped because scans show ned.  Hope all goes well with your second infusion.

                    • August 28, 2017 at 6:22 am
                    Scooby123
                    Participant

                      Thanks Kristi, so pleased for you, I have arthritis already and my back is really bad at moment taking pain killers to help. 

                    • August 28, 2017 at 11:56 am
                    ed williams
                    Participant

                      Hi Scooby, here is a link to a recent presentation from Dr. Postow on Immunotherapy side effects. http://learn.peerviewpress.com/p/index.html?collection=150204255-2-2&presentationid=p3&SpecialtyID=74&ProfessionID=12&Promocode=815#screen1

                        • August 28, 2017 at 8:25 pm
                        Scooby123
                        Participant

                          Thanks ED for info some bed time reading. Hope you are well. X

                           

                          • August 29, 2017 at 4:16 pm
                          jrtufo
                          Participant

                            I had a weird reaction after my second infusion-I lost the hearing in one of my ears!  Caught it right away and predinsone took care of it straight away.  Had five more infusions and only sufferred from a bit of fatigue, but unfortunately my tumor kept growing so changed treatment plans.

                            • August 30, 2017 at 9:26 pm
                            Scooby123
                            Participant

                              Thank you ❤️

                            • August 28, 2017 at 9:34 pm
                            Bradley75
                            Participant

                              I have been on Keytruda for over 6 months now.  I have a minor rash from time to time and a little bit of fatigue.  My only other side effect is joint stiffness.  I walk like an old man for a few days after each treatment.  All in all none of my side effects have been difficult to live with.  Best of luck to you tomorrow.

                              Brad

                                • August 30, 2017 at 9:27 pm
                                Scooby123
                                Participant

                                  Thank you❤️

                                • August 30, 2017 at 2:41 pm
                                mrsaxde
                                Participant

                                  Hi Scooby,

                                  Even though you've gotten a good number of responses I thought I'd weigh in, too. I was on Keytruda for about 1.5 years. The only side effects I experienced were a mild rash and moderate itching, and some mild fatigue that seemed to get worse the more infusions I had, but was never so bad as to be debilitating. Not nearly as bad as the side effects I experienced from ipi.

                                  -Bill

                                    • August 30, 2017 at 9:27 pm
                                    Scooby123
                                    Participant

                                      Thank you❤️

                                    • August 30, 2017 at 2:47 pm
                                    Nick C
                                    Participant

                                      Hi Scooby,

                                      I've been on Keytruda for 8 months and have had no side effects. Hope the same for you.

                                      Nick

                                        • August 30, 2017 at 9:27 pm
                                        Scooby123
                                        Participant

                                          Thank you❤️

                                        • September 20, 2017 at 7:20 pm
                                        MikeW
                                        Participant

                                          Been a couple months since I was on the board….hope this still helps. I had three infusions of Keytruda and had the rash/itchiness that ended up going away. The thing that surprised us was autom-immune arthritis. It was bad enough to discountinue treatment. It's been treated with prednisone and the symptoms are almost gone. Fortunately, I've had two clean scans. 

                                      Viewing 6 reply threads
                                      • You must be logged in to reply to this topic.
                                      About the MRF Patient Forum

                                      The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                                      The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

                                      Popular Topics