› Forums › General Melanoma Community › Keytruda side effects (melanoma stage IV)
- This topic has 6 replies, 2 voices, and was last updated 7 years, 10 months ago by
thinkingofu.
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- July 28, 2017 at 1:31 pm
Hello everyone
Thank you so much for being so helpful in the past. I have another question regarding your experience with treatment.
My mother has stage IV Melanoma, mets in brain (3) and in the lung (1).
There was swelling in her brain caused by two of the mets (liquid around them) which was taken care of during the operation. Two of the mets were taken out during the op and 1 is still there.
We are preparing to move her to another hospital, but doctors are considering giving her first round of treatment now.
We have mentioned Keytruda to them which they know about and think it may be helpful, but they are saying that Keytruda may produce another swelling (liquid) in her brain.
Is that a known side effect of Keytruda and other immunotheraphy drugs?
Thank you
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- July 28, 2017 at 7:53 pm
Hi thinkingofu, I have a link for you of a top Melanoma Oncology panel talking about the newest data and best way to attack brain mets. Best Wishes!!!Ed https://www.youtube.com/watch?v=X5xGQpdp9OA
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- July 29, 2017 at 9:50 am
Thank you ! xoxo
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- July 29, 2017 at 10:47 am
This is so interesting. Thank you again so so much xxxx
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- July 29, 2017 at 12:03 pm
Hi thinkingofu, the study data of using Ipi/nivo in the brain done in Australia by Dr. Long is in the following link from ASCO in June of this year!!! http://abstracts.asco.org/199/AbstView_199_187928.html The dose is Ipi every 3 weeks for a total of 4 treatments at 3mg/kg. Nivo is given every two weeks at 1mg/kg. This second link is to the actual trial. https://clinicaltrials.gov/show/NCT02374242
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- July 29, 2017 at 12:07 pm
In the states I know they are running a trial called checkmate 204 and Dr. Omid Hamid at the Angeles Clinic in California is one of the locations. Here is a link to his clinic and go down to Melanoma and then at bottom of page it talks about Melanoma and brain mets trials with Immunotherapy drugs. http://www.theangelesclinic.org/Home/ResearchClinicalTrials/ClinicalTrialList/tabid/19278/Default.aspx#Melanoma
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- July 29, 2017 at 3:58 pm
Thank you!!! xxx
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