The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

KRAS mutation treatment?

Forums General Melanoma Community KRAS mutation treatment?

  • This topic is empty.
  • Post
    JerryfromFauq
    Participant

      Some melanomas have KRAS, some have both KRAS andBRAF.

       

      http://www.sciencedaily.com/releases/2012/01/120111090607.htm

      Some melanomas have KRAS, some have both KRAS andBRAF.

       

      http://www.sciencedaily.com/releases/2012/01/120111090607.htm

      Ganetespib Showed Activity in KRAS-Mutant NSCLC as Monotherapy and in Combinations

      ScienceDaily (Jan. 10, 2012) — The investigational drug ganetespib, a synthetic second-generation Hsp90 inhibitor, slowed the growth of cancer cells taken from non-small cell lung cancer tumors with a mutation in the KRAS gene. The drug was even more active when combined with traditional lung cancer treatments and other investigational targeted therapies, according to preclinical study data.


      Share This:
      David A. Proia, Ph.D., and Jaime Acquaviva, Ph.D., scientists at Synta Pharmaceuticals Corp., presented the data at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Biology, Therapy and Personalized Medicine, held Jan. 8-11, 2012.
    • You must be logged in to reply to this topic.
    About the MRF Patient Forum

    The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

    The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.