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LDH increasing after start of Keytruda?
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LDH increasing after start of Keytruda?

› Forums › General Melanoma Community › LDH increasing after start of Keytruda?

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    • October 29, 2017 at 3:13 pm
    MovingOn
    Participant

      I had my second Keytruda infusion this past Monday. On 8/24 my LDH was 160. 9/27 it was 139. 10/25 it is 266. 

      Mom thinking this could mean that additional tumors are growing or it could mean that Keytruda is causing cell death (hopefully tumor cell death). My palpable tumors are definitely smaller but I’m not going to ‘count my chickens before they hatch.’

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        • October 29, 2017 at 3:14 pm
        MovingOn
        Participant

          In the second paragraph it should start with “I’m” rather than “mom” (either my fingers are fatter today or spell check is telling me to call my mom this weekend).

          • October 30, 2017 at 2:54 am
          TexMelanomex
          Participant

            Interesting. My money is on the Keytruda kicking some Mel butt, especially if you are noticing obvious decrease in palpable tumor size…I'm on for my second round on Tuesday and I'll let you know what (if anything) happens with my LDH once the labs come back in. Mine are already signficantly higher to start with, but I'll be interested to see if they change with the Keytruda on board.

             

            Tex

            • November 2, 2017 at 8:45 pm
            Mat
            Participant

              Your level is still close to normal.  LDH is not considered a definitive marker when off treatment–even less so when on treatment.

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