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New Targeted Therapy Approved Today!!!
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New Targeted Therapy Approved Today!!!

› Forums › General Melanoma Community › New Targeted Therapy Approved Today!!!

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      • June 28, 2018 at 1:45 am
      Bubbles
      Participant

        Hey Edster!!

        Was just writing a post about this myself.  I think this approval is a good thing.  But, I fear I am a bit more cynical when I break down the data.    My main problem with the data and study is that they compared this combo to vemurafenib alone.  We have known for YEARS that any BRAF/MEK combo does better than BRAFi alone!!!!!  

        Here is the post I put together just now with info from posts I put up in May of 2017 and in March of this year – looking at the Columbus Study: 

         http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2018/06/well-okie-dokie-braftovimektovi.html  

        Again, not saying this is bad news.  I'd probably try this combo if I had the need.  BUT…just keep'n it 100!!!!

        love you.  c

        • June 28, 2018 at 9:33 am
        Tracyyy
        Participant

          Thanks for the info, Ed! Is there any info yet if the new combo will be effective in case that TAF/MEK stops working?

            • June 28, 2018 at 11:21 am
            ed williams
            Participant

              I have two links for you, first one is from last fall and is about Columbus trial, explaining how it works. Starts at 2:30 min mark. Second link is from last July Onclive panel and topic comes up about what to do when targeted therapy stops working, go to 3:20 min mark, Dr. Michael Davies of MD Anderson explains research in this area.https://www.youtube.com/watch?v=8uAudb1-jCs                https://www.youtube.com/watch?v=t_bFid7Tx7s

              • June 28, 2018 at 12:21 pm
              Tracyyy
              Participant
                Huge thanks! Wish there was a like button here…
                • July 16, 2018 at 9:57 pm
                CPM0720
                Participant

                  Thanks for these!

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