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Others on Ipi/Nivo w/ fever & chills

Forums General Melanoma Community Others on Ipi/Nivo w/ fever & chills

  • Post
    jennunicorn
    Participant

      I will first say that I will be calling my onc's office in the morning if I still feel this way, and will email if I feel better but still want to let them know.

      Just wondering for others who have been on or are on the Ipi/Nivo combo and have experienced low grade fever, body aches, and chills…. did you find a cause, if so what was it? How long did it last?

      I had my 4th dose on 12/29 and have never felt this before. Appetite was gone yesterday and today, I've had some on and off appetite loss throughout the combo, so that part is not new. Now I have a low grade fever, 99.2 last time I checked and my body aches pretty bad and chills are not fun either. I got a flu shot a couple of months ago, so I don't think I have the flu.

      My labs last week showed very slightly high white blood cell count and slight anemia. Onc wasn't concerned. She asked me if I had been feeling sick and I had not.. until now.. that was 5 days ago.

      Any insight would be great, thanks!

    Viewing 23 reply threads
    • Replies
        Buddy0513
        Participant
          Hi Jenn,

          This actually happened to my mom twice after 2 of her combo treatments. She ended up feeling very fatigued, cold, chills and wasn’t able to eat, she also had pain in her hips and bones like she had never felt before. She had a fever of 100.5 the one time. When we asked the Dr what it was, he said it was the immunotherapy (I also remember reading these came as side effects in a packet he gave me) and that if she didn’t have a fever over 101.5 to not worry. He didn’t seem alarmed either time we told him and nothing was prescribed to her.

          She was sick for about 1.5 days (slept a lot during this time) then on the 3rd day after she was fine. We never did figure out what it was from. She had elevated WBC as well, but low protein levels no anemia.

          Best advice would stay hydrated (that’s about all my mom could do as well since she had no appetite) and just rest. Call your Dr to make sure anyway since everyone’s situation is different. Hope this helps a bit!

          Buddy0513
          Participant
            Hi Jenn,

            This actually happened to my mom twice after 2 of her combo treatments. She ended up feeling very fatigued, cold, chills and wasn’t able to eat, she also had pain in her hips and bones like she had never felt before. She had a fever of 100.5 the one time. When we asked the Dr what it was, he said it was the immunotherapy (I also remember reading these came as side effects in a packet he gave me) and that if she didn’t have a fever over 101.5 to not worry. He didn’t seem alarmed either time we told him and nothing was prescribed to her.

            She was sick for about 1.5 days (slept a lot during this time) then on the 3rd day after she was fine. We never did figure out what it was from. She had elevated WBC as well, but low protein levels no anemia.

            Best advice would stay hydrated (that’s about all my mom could do as well since she had no appetite) and just rest. Call your Dr to make sure anyway since everyone’s situation is different. Hope this helps a bit!

            Buddy0513
            Participant
              Hi Jenn,

              This actually happened to my mom twice after 2 of her combo treatments. She ended up feeling very fatigued, cold, chills and wasn’t able to eat, she also had pain in her hips and bones like she had never felt before. She had a fever of 100.5 the one time. When we asked the Dr what it was, he said it was the immunotherapy (I also remember reading these came as side effects in a packet he gave me) and that if she didn’t have a fever over 101.5 to not worry. He didn’t seem alarmed either time we told him and nothing was prescribed to her.

              She was sick for about 1.5 days (slept a lot during this time) then on the 3rd day after she was fine. We never did figure out what it was from. She had elevated WBC as well, but low protein levels no anemia.

              Best advice would stay hydrated (that’s about all my mom could do as well since she had no appetite) and just rest. Call your Dr to make sure anyway since everyone’s situation is different. Hope this helps a bit!

                jennunicorn
                Participant
                  Thanks Melissa, that does help! Glad it was nothing serious and didn’t last too long for her.
                  jennunicorn
                  Participant
                    Thanks Melissa, that does help! Glad it was nothing serious and didn’t last too long for her.
                    jennunicorn
                    Participant
                      Thanks Melissa, that does help! Glad it was nothing serious and didn’t last too long for her.
                      Buddy0513
                      Participant
                        Glad to help! We were worried out of our minds the first time it happened so I definitely understand the worry! Hope you feel better and that it passes soon. Keep us updated here how it goes.
                        Buddy0513
                        Participant
                          Glad to help! We were worried out of our minds the first time it happened so I definitely understand the worry! Hope you feel better and that it passes soon. Keep us updated here how it goes.
                          Buddy0513
                          Participant
                            Glad to help! We were worried out of our minds the first time it happened so I definitely understand the worry! Hope you feel better and that it passes soon. Keep us updated here how it goes.
                          jennunicorn
                          Participant

                            Just took my temp again: 100.6 now

                            I can count on one hand the amount of times I have had a fever in my life, so this is weird to me, these body aches suck!

                            jennunicorn
                            Participant

                              Just took my temp again: 100.6 now

                              I can count on one hand the amount of times I have had a fever in my life, so this is weird to me, these body aches suck!

                              jennunicorn
                              Participant

                                Just took my temp again: 100.6 now

                                I can count on one hand the amount of times I have had a fever in my life, so this is weird to me, these body aches suck!

                                  Buddy0513
                                  Participant
                                    Oh gosh. Definitely keep an eye. If it gets any higher by the morning I would call your Dr to make sure he doesn’t want to run extra blood work or anything. I can’t even say I would recommend Tylenol, my mom tried it and it didn’t do a thing for the aches or fever. Again, it may be different for you, we just kept trying to avoid putting more stressors in her body with additional medicines, but it may work for you.
                                    Buddy0513
                                    Participant
                                      Oh gosh. Definitely keep an eye. If it gets any higher by the morning I would call your Dr to make sure he doesn’t want to run extra blood work or anything. I can’t even say I would recommend Tylenol, my mom tried it and it didn’t do a thing for the aches or fever. Again, it may be different for you, we just kept trying to avoid putting more stressors in her body with additional medicines, but it may work for you.
                                      Buddy0513
                                      Participant
                                        Oh gosh. Definitely keep an eye. If it gets any higher by the morning I would call your Dr to make sure he doesn’t want to run extra blood work or anything. I can’t even say I would recommend Tylenol, my mom tried it and it didn’t do a thing for the aches or fever. Again, it may be different for you, we just kept trying to avoid putting more stressors in her body with additional medicines, but it may work for you.
                                        jennunicorn
                                        Participant

                                          Another update: 101.2 now

                                          Took more Tylenol since it's been a few hours since I took it last. If it doesn't help and fever goes up more then I may need to take a trip to the ER.

                                          jennunicorn
                                          Participant

                                            Another update: 101.2 now

                                            Took more Tylenol since it's been a few hours since I took it last. If it doesn't help and fever goes up more then I may need to take a trip to the ER.

                                            jennunicorn
                                            Participant

                                              Another update: 101.2 now

                                              Took more Tylenol since it's been a few hours since I took it last. If it doesn't help and fever goes up more then I may need to take a trip to the ER.

                                            Patina
                                            Participant
                                              My Mon experienced this will ipi. Was in the ER and hospital twice. They couldn’t find anything. All she needed to do was take Tylenol if it started and she was fine. If this doesn’t work call your doctor.
                                              Patina
                                              Participant
                                                My Mon experienced this will ipi. Was in the ER and hospital twice. They couldn’t find anything. All she needed to do was take Tylenol if it started and she was fine. If this doesn’t work call your doctor.
                                                Patina
                                                Participant
                                                  My Mon experienced this will ipi. Was in the ER and hospital twice. They couldn’t find anything. All she needed to do was take Tylenol if it started and she was fine. If this doesn’t work call your doctor.
                                                    jennunicorn
                                                    Participant

                                                      Thanks Patina, I took Tylenol a couple of hours ago, will take another one in a little while and see if it does anything. 

                                                      jennunicorn
                                                      Participant

                                                        Thanks Patina, I took Tylenol a couple of hours ago, will take another one in a little while and see if it does anything. 

                                                        jennunicorn
                                                        Participant

                                                          Thanks Patina, I took Tylenol a couple of hours ago, will take another one in a little while and see if it does anything. 

                                                        chalroad5
                                                        Participant

                                                          I experienced some of the same side effects immediately after my second ipi/nivo infusion (and my third overall infusion, since I had started with a single dose of nivo). For about a month, I was running a pretty high fever, around 101-02, that we kept in check with a steady stream of ibuprofen and tylenol. Also, I was extremely fatigued throughout the month, had constant chills and headaches, had very little appetite, and mostly kept to my bed or couch.

                                                          Prior to getting my third combo infusion, my bloodwork showed elevated liver enzymes (about 5x ULN). My doctor decided to postpone any further treatment and instead started me on a pretty heavy daily steroid regimen. I felt better almost instaneously and these side effects quickly subsided (although others lingered for quite a while longer).

                                                          I think the thinking is that, in my case, all of the side effects, including the fevers and hepatoxicity, were immunotherapy-related. Fortunately, while going into overdrive, my immune system seemed to have destroyed a lot of cancer, too.

                                                          By the way, I was treated at UCSF. As I'm sure you have, I received very attentive and responsive care from the physicians and staff both during and outside of working hours. So don't hesitate to get in touch at any time because, at the very least, there will be an oncologist on call to handle side effect concerns.

                                                          chalroad5
                                                          Participant

                                                            I experienced some of the same side effects immediately after my second ipi/nivo infusion (and my third overall infusion, since I had started with a single dose of nivo). For about a month, I was running a pretty high fever, around 101-02, that we kept in check with a steady stream of ibuprofen and tylenol. Also, I was extremely fatigued throughout the month, had constant chills and headaches, had very little appetite, and mostly kept to my bed or couch.

                                                            Prior to getting my third combo infusion, my bloodwork showed elevated liver enzymes (about 5x ULN). My doctor decided to postpone any further treatment and instead started me on a pretty heavy daily steroid regimen. I felt better almost instaneously and these side effects quickly subsided (although others lingered for quite a while longer).

                                                            I think the thinking is that, in my case, all of the side effects, including the fevers and hepatoxicity, were immunotherapy-related. Fortunately, while going into overdrive, my immune system seemed to have destroyed a lot of cancer, too.

                                                            By the way, I was treated at UCSF. As I'm sure you have, I received very attentive and responsive care from the physicians and staff both during and outside of working hours. So don't hesitate to get in touch at any time because, at the very least, there will be an oncologist on call to handle side effect concerns.

                                                            chalroad5
                                                            Participant

                                                              I experienced some of the same side effects immediately after my second ipi/nivo infusion (and my third overall infusion, since I had started with a single dose of nivo). For about a month, I was running a pretty high fever, around 101-02, that we kept in check with a steady stream of ibuprofen and tylenol. Also, I was extremely fatigued throughout the month, had constant chills and headaches, had very little appetite, and mostly kept to my bed or couch.

                                                              Prior to getting my third combo infusion, my bloodwork showed elevated liver enzymes (about 5x ULN). My doctor decided to postpone any further treatment and instead started me on a pretty heavy daily steroid regimen. I felt better almost instaneously and these side effects quickly subsided (although others lingered for quite a while longer).

                                                              I think the thinking is that, in my case, all of the side effects, including the fevers and hepatoxicity, were immunotherapy-related. Fortunately, while going into overdrive, my immune system seemed to have destroyed a lot of cancer, too.

                                                              By the way, I was treated at UCSF. As I'm sure you have, I received very attentive and responsive care from the physicians and staff both during and outside of working hours. So don't hesitate to get in touch at any time because, at the very least, there will be an oncologist on call to handle side effect concerns.

                                                                jennunicorn
                                                                Participant

                                                                  Thanks for the info.

                                                                  I am waiting for the on call doctor to call me… it's taking longer than I'd like. Fever went up to 101.6 and then an hour later down to 100.4.. so, who knows, but hopefully I can talk to someone and get an oncologist opinion on this.

                                                                  jennunicorn
                                                                  Participant

                                                                    Thanks for the info.

                                                                    I am waiting for the on call doctor to call me… it's taking longer than I'd like. Fever went up to 101.6 and then an hour later down to 100.4.. so, who knows, but hopefully I can talk to someone and get an oncologist opinion on this.

                                                                    jennunicorn
                                                                    Participant

                                                                      Thanks for the info.

                                                                      I am waiting for the on call doctor to call me… it's taking longer than I'd like. Fever went up to 101.6 and then an hour later down to 100.4.. so, who knows, but hopefully I can talk to someone and get an oncologist opinion on this.

                                                                      jennunicorn
                                                                      Participant
                                                                        In the ER since on call doc said it’s better to be safe than sorry. Fever has gone down and I’m feeling less achy than earlier. Getting blood work done and have IV fluids in now.
                                                                        jennunicorn
                                                                        Participant
                                                                          In the ER since on call doc said it’s better to be safe than sorry. Fever has gone down and I’m feeling less achy than earlier. Getting blood work done and have IV fluids in now.
                                                                          jennunicorn
                                                                          Participant
                                                                            In the ER since on call doc said it’s better to be safe than sorry. Fever has gone down and I’m feeling less achy than earlier. Getting blood work done and have IV fluids in now.
                                                                            keepthefaith11
                                                                            Participant
                                                                              Jenn, how are you feelimg today? The flu shot does not cover all the strains of the flu. So that could still be a possibility. Or some other virus. But also highly likely it might be immunotherapy related. My Dad ran a fever of 104 for a day or so while on Yervoy. Keep us updated.

                                                                              Annie

                                                                              jennunicorn
                                                                              Participant

                                                                                Very tired and body still achy, didn't get good sleep. Fever is staying down to 100 with Tylenol. Blood work was all normal, no infection found, doc said could be a bug I picked up or could just be immune system going a little wacky from treatment. Hopefully I feel more normal tomorrow if I can rest up today.

                                                                                jennunicorn
                                                                                Participant

                                                                                  Very tired and body still achy, didn't get good sleep. Fever is staying down to 100 with Tylenol. Blood work was all normal, no infection found, doc said could be a bug I picked up or could just be immune system going a little wacky from treatment. Hopefully I feel more normal tomorrow if I can rest up today.

                                                                                  jennunicorn
                                                                                  Participant

                                                                                    Very tired and body still achy, didn't get good sleep. Fever is staying down to 100 with Tylenol. Blood work was all normal, no infection found, doc said could be a bug I picked up or could just be immune system going a little wacky from treatment. Hopefully I feel more normal tomorrow if I can rest up today.

                                                                                    keepthefaith11
                                                                                    Participant
                                                                                      Jenn, how are you feelimg today? The flu shot does not cover all the strains of the flu. So that could still be a possibility. Or some other virus. But also highly likely it might be immunotherapy related. My Dad ran a fever of 104 for a day or so while on Yervoy. Keep us updated.

                                                                                      Annie

                                                                                      keepthefaith11
                                                                                      Participant
                                                                                        Jenn, how are you feelimg today? The flu shot does not cover all the strains of the flu. So that could still be a possibility. Or some other virus. But also highly likely it might be immunotherapy related. My Dad ran a fever of 104 for a day or so while on Yervoy. Keep us updated.

                                                                                        Annie

                                                                                      Hukill
                                                                                      Participant

                                                                                        Around my third dose of the combo I started running fever and it lasted 6 weeks. Spent several days in the hospital at first running every test for infection, nothing. Doc finally agreed it was a side effect. It was the worst chills I have ever had. I would sit in my hot tub in july shivering. I learned that If I took motrin every 2 hours the fever stayed under control. If I stopped to see if the fever came back it would and then I would go through the whole cycle of chills and sweats. I was even sleeping on a cot with a plastic pad with a stack of sheets beside me. During the night I would soak a sheet, discard it, slap a dry sheet on. Lasted about 6 weeks and have not had any since.

                                                                                          jennunicorn
                                                                                          Participant

                                                                                            That sounds awful, but I'm glad it wasn't from something more serious going on. Thankfully the chills have subsided and I'm left with a very achy body… kinda feels like I got hit by a car. Hopefully this doesn't last too long for me. Had a bunch of blood work, cultures, and other tests run at ER, all came back normal which is good.

                                                                                            Elana
                                                                                            Participant

                                                                                              Hey Jenn,

                                                                                              I was on Ipi (for stage IIIB) but only made it through 2 infusion. A week after my first infusion I had 1 day of low-grade fever/chills/body aches and then it went away. Then right be fore my 2nd infusion I had 2 days of low-grade fever and chills. After my 2nd infusion, that evening my fever went up to 102. It was thanksgiving weekend and I called my onc that evening, he told me to just to take ibuprofen and call if it got worse. They had taken a bunch of blood cultures and UA before my infusion and everything came back normal. The fevers continued for a week straight. the highest it got was 103.2. Just like one of the other posters said I would sleep with towels and blankets under me and have to change my clothes/sheets like 3 times a night. I could control the fevers with ibuprofen but they would come right back once it wore off. I would have shaking chills and then my fever would break and I would sweat like crazy. I did not lose my appetite which was strange. Eventualy after 5 days of this I told my onc and he finally told me to go to the ER. They ran a bunch of tests and everything came back normal except my platelets were low (92,000) and I was mildly anemic. They stupidly didn't run a liver panel. I went and saw my onc the following monday and my LFTs were 2x the normal limit.  They started me on prednisone and the fevers went away immediately. They thought I had autoimmune hepatitis (since 2 days later my LFT's were still trending up even with the prednisone) and I had a liver biopsy with mixed results (liver toxicity injury vs autoimmune hepatits). After being on 60 mg of prednisone for a week we did a fast taper and I finished it 2 weeks later. Everything was normal. That was 2 weeks ago. We discontinued the Ipi after my 2nd infusion since i have NED after surgery and the side effects were terrible. However last night I had a fever of 102.9 again. Not sure what's going on but going back to MGH today or tomorrow. Make sure they check your LFTs! Hoping I don't have to start prednisone again. Best of luck to you!

                                                                                              jennunicorn
                                                                                              Participant

                                                                                                Thanks for sharing Elana, sorry you got put through a lot with just a couple infusions. They did check liver funtion as part of the blood tests, it's in normal range. If my fever rises again I will get in to see my oncologist and have bloods and everything tested again, since she knows exactly what to test for with this kind of stuff.

                                                                                                Hope your fevers stop soon too!

                                                                                                jennunicorn
                                                                                                Participant

                                                                                                  Thanks for sharing Elana, sorry you got put through a lot with just a couple infusions. They did check liver funtion as part of the blood tests, it's in normal range. If my fever rises again I will get in to see my oncologist and have bloods and everything tested again, since she knows exactly what to test for with this kind of stuff.

                                                                                                  Hope your fevers stop soon too!

                                                                                                  jennunicorn
                                                                                                  Participant

                                                                                                    Thanks for sharing Elana, sorry you got put through a lot with just a couple infusions. They did check liver funtion as part of the blood tests, it's in normal range. If my fever rises again I will get in to see my oncologist and have bloods and everything tested again, since she knows exactly what to test for with this kind of stuff.

                                                                                                    Hope your fevers stop soon too!

                                                                                                    Elana
                                                                                                    Participant

                                                                                                      Hey Jenn,

                                                                                                      I was on Ipi (for stage IIIB) but only made it through 2 infusion. A week after my first infusion I had 1 day of low-grade fever/chills/body aches and then it went away. Then right be fore my 2nd infusion I had 2 days of low-grade fever and chills. After my 2nd infusion, that evening my fever went up to 102. It was thanksgiving weekend and I called my onc that evening, he told me to just to take ibuprofen and call if it got worse. They had taken a bunch of blood cultures and UA before my infusion and everything came back normal. The fevers continued for a week straight. the highest it got was 103.2. Just like one of the other posters said I would sleep with towels and blankets under me and have to change my clothes/sheets like 3 times a night. I could control the fevers with ibuprofen but they would come right back once it wore off. I would have shaking chills and then my fever would break and I would sweat like crazy. I did not lose my appetite which was strange. Eventualy after 5 days of this I told my onc and he finally told me to go to the ER. They ran a bunch of tests and everything came back normal except my platelets were low (92,000) and I was mildly anemic. They stupidly didn't run a liver panel. I went and saw my onc the following monday and my LFTs were 2x the normal limit.  They started me on prednisone and the fevers went away immediately. They thought I had autoimmune hepatitis (since 2 days later my LFT's were still trending up even with the prednisone) and I had a liver biopsy with mixed results (liver toxicity injury vs autoimmune hepatits). After being on 60 mg of prednisone for a week we did a fast taper and I finished it 2 weeks later. Everything was normal. That was 2 weeks ago. We discontinued the Ipi after my 2nd infusion since i have NED after surgery and the side effects were terrible. However last night I had a fever of 102.9 again. Not sure what's going on but going back to MGH today or tomorrow. Make sure they check your LFTs! Hoping I don't have to start prednisone again. Best of luck to you!

                                                                                                      Elana
                                                                                                      Participant

                                                                                                        Hey Jenn,

                                                                                                        I was on Ipi (for stage IIIB) but only made it through 2 infusion. A week after my first infusion I had 1 day of low-grade fever/chills/body aches and then it went away. Then right be fore my 2nd infusion I had 2 days of low-grade fever and chills. After my 2nd infusion, that evening my fever went up to 102. It was thanksgiving weekend and I called my onc that evening, he told me to just to take ibuprofen and call if it got worse. They had taken a bunch of blood cultures and UA before my infusion and everything came back normal. The fevers continued for a week straight. the highest it got was 103.2. Just like one of the other posters said I would sleep with towels and blankets under me and have to change my clothes/sheets like 3 times a night. I could control the fevers with ibuprofen but they would come right back once it wore off. I would have shaking chills and then my fever would break and I would sweat like crazy. I did not lose my appetite which was strange. Eventualy after 5 days of this I told my onc and he finally told me to go to the ER. They ran a bunch of tests and everything came back normal except my platelets were low (92,000) and I was mildly anemic. They stupidly didn't run a liver panel. I went and saw my onc the following monday and my LFTs were 2x the normal limit.  They started me on prednisone and the fevers went away immediately. They thought I had autoimmune hepatitis (since 2 days later my LFT's were still trending up even with the prednisone) and I had a liver biopsy with mixed results (liver toxicity injury vs autoimmune hepatits). After being on 60 mg of prednisone for a week we did a fast taper and I finished it 2 weeks later. Everything was normal. That was 2 weeks ago. We discontinued the Ipi after my 2nd infusion since i have NED after surgery and the side effects were terrible. However last night I had a fever of 102.9 again. Not sure what's going on but going back to MGH today or tomorrow. Make sure they check your LFTs! Hoping I don't have to start prednisone again. Best of luck to you!

                                                                                                        jennunicorn
                                                                                                        Participant

                                                                                                          That sounds awful, but I'm glad it wasn't from something more serious going on. Thankfully the chills have subsided and I'm left with a very achy body… kinda feels like I got hit by a car. Hopefully this doesn't last too long for me. Had a bunch of blood work, cultures, and other tests run at ER, all came back normal which is good.

                                                                                                          jennunicorn
                                                                                                          Participant

                                                                                                            That sounds awful, but I'm glad it wasn't from something more serious going on. Thankfully the chills have subsided and I'm left with a very achy body… kinda feels like I got hit by a car. Hopefully this doesn't last too long for me. Had a bunch of blood work, cultures, and other tests run at ER, all came back normal which is good.

                                                                                                          Hukill
                                                                                                          Participant

                                                                                                            Around my third dose of the combo I started running fever and it lasted 6 weeks. Spent several days in the hospital at first running every test for infection, nothing. Doc finally agreed it was a side effect. It was the worst chills I have ever had. I would sit in my hot tub in july shivering. I learned that If I took motrin every 2 hours the fever stayed under control. If I stopped to see if the fever came back it would and then I would go through the whole cycle of chills and sweats. I was even sleeping on a cot with a plastic pad with a stack of sheets beside me. During the night I would soak a sheet, discard it, slap a dry sheet on. Lasted about 6 weeks and have not had any since.

                                                                                                            Hukill
                                                                                                            Participant

                                                                                                              Around my third dose of the combo I started running fever and it lasted 6 weeks. Spent several days in the hospital at first running every test for infection, nothing. Doc finally agreed it was a side effect. It was the worst chills I have ever had. I would sit in my hot tub in july shivering. I learned that If I took motrin every 2 hours the fever stayed under control. If I stopped to see if the fever came back it would and then I would go through the whole cycle of chills and sweats. I was even sleeping on a cot with a plastic pad with a stack of sheets beside me. During the night I would soak a sheet, discard it, slap a dry sheet on. Lasted about 6 weeks and have not had any since.

                                                                                                              Mat
                                                                                                              Participant

                                                                                                                I've had about 20 nivo infusions (including the combined ipi-nivo infusions).  I also was on pembro in 2015.  Every few weeks or so, I have a low grade fever (including while on antibiotics).  Usually under 100.  Comes and goes and I manage it with Tylenol.  I agree that a trip to the ER makes sense for a higher fever like yours.  Good luck.

                                                                                                                  jennunicorn
                                                                                                                  Participant

                                                                                                                    Thanks Mat! My onc said if it continues then I'll be put on steroids to calm my body down. I'm kind of glad to get a reaction like this out of my body as treatment has gone super smooth for me..  I'm just hoping this means my immune system is in super kick ass mode and it's getting stuff done! πŸ™‚

                                                                                                                    jennunicorn
                                                                                                                    Participant

                                                                                                                      Thanks Mat! My onc said if it continues then I'll be put on steroids to calm my body down. I'm kind of glad to get a reaction like this out of my body as treatment has gone super smooth for me..  I'm just hoping this means my immune system is in super kick ass mode and it's getting stuff done! πŸ™‚

                                                                                                                      jennunicorn
                                                                                                                      Participant

                                                                                                                        Thanks Mat! My onc said if it continues then I'll be put on steroids to calm my body down. I'm kind of glad to get a reaction like this out of my body as treatment has gone super smooth for me..  I'm just hoping this means my immune system is in super kick ass mode and it's getting stuff done! πŸ™‚

                                                                                                                      Mat
                                                                                                                      Participant

                                                                                                                        I've had about 20 nivo infusions (including the combined ipi-nivo infusions).  I also was on pembro in 2015.  Every few weeks or so, I have a low grade fever (including while on antibiotics).  Usually under 100.  Comes and goes and I manage it with Tylenol.  I agree that a trip to the ER makes sense for a higher fever like yours.  Good luck.

                                                                                                                        Mat
                                                                                                                        Participant

                                                                                                                          I've had about 20 nivo infusions (including the combined ipi-nivo infusions).  I also was on pembro in 2015.  Every few weeks or so, I have a low grade fever (including while on antibiotics).  Usually under 100.  Comes and goes and I manage it with Tylenol.  I agree that a trip to the ER makes sense for a higher fever like yours.  Good luck.

                                                                                                                          Aloha14
                                                                                                                          Participant

                                                                                                                            I just wanted to say that I hope your feeling better soon.

                                                                                                                            Aloha14
                                                                                                                            Participant

                                                                                                                              I just wanted to say that I hope your feeling better soon.

                                                                                                                              Aloha14
                                                                                                                              Participant

                                                                                                                                I just wanted to say that I hope your feeling better soon.

                                                                                                                                Mark_DC
                                                                                                                                Participant

                                                                                                                                  Jenn, hope it was just a cold or flu or something like that

                                                                                                                                  had same thing two weeks ago (am on pembro) but this was not the pembro just a sore throat and cold

                                                                                                                                  i also dont usually get fever so was surprised and emailed my doctor (no ER)

                                                                                                                                  am a little surprised you take tylenol and not ibuprofen: i tend to get bad liver readings and my doctors prohibit tylenol (alcohol too!) – but your liver readings seem ok

                                                                                                                                  hope you are feeling better take care mark

                                                                                                                                    jennunicorn
                                                                                                                                    Participant

                                                                                                                                      Thanks Mark. I don't usually take Tylenol, but my doc said it was ok to take to keep fever down. Liver tests are normal so no worries there. Hope you're feeling better after your cold.

                                                                                                                                      jennunicorn
                                                                                                                                      Participant

                                                                                                                                        Thanks Mark. I don't usually take Tylenol, but my doc said it was ok to take to keep fever down. Liver tests are normal so no worries there. Hope you're feeling better after your cold.

                                                                                                                                        jennunicorn
                                                                                                                                        Participant

                                                                                                                                          Thanks Mark. I don't usually take Tylenol, but my doc said it was ok to take to keep fever down. Liver tests are normal so no worries there. Hope you're feeling better after your cold.

                                                                                                                                        Mark_DC
                                                                                                                                        Participant

                                                                                                                                          Jenn, hope it was just a cold or flu or something like that

                                                                                                                                          had same thing two weeks ago (am on pembro) but this was not the pembro just a sore throat and cold

                                                                                                                                          i also dont usually get fever so was surprised and emailed my doctor (no ER)

                                                                                                                                          am a little surprised you take tylenol and not ibuprofen: i tend to get bad liver readings and my doctors prohibit tylenol (alcohol too!) – but your liver readings seem ok

                                                                                                                                          hope you are feeling better take care mark

                                                                                                                                          Mark_DC
                                                                                                                                          Participant

                                                                                                                                            Jenn, hope it was just a cold or flu or something like that

                                                                                                                                            had same thing two weeks ago (am on pembro) but this was not the pembro just a sore throat and cold

                                                                                                                                            i also dont usually get fever so was surprised and emailed my doctor (no ER)

                                                                                                                                            am a little surprised you take tylenol and not ibuprofen: i tend to get bad liver readings and my doctors prohibit tylenol (alcohol too!) – but your liver readings seem ok

                                                                                                                                            hope you are feeling better take care mark

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