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Question about ALDARA -Jim Breitfeller or anyone

Forums Cutaneous Melanoma Community Question about ALDARA -Jim Breitfeller or anyone

  • Post
    killmel
    Participant

      Jim or anyone with  knowledge about aldara,

      Jim,you mentioned in a previous post:

      Jim or anyone with  knowledge about aldara,

      Jim,you mentioned in a previous post:

      "Imiquimod also has antitumor activity, which might stem from the drug’s ability to stimulate a cell-mediated immune response. Application of imiquimod also leads to the release of IL-12, tumor necrosis factor α, and interferon α, which inhibit angiogenesis and increase cytotoxic T cells and natural killer cells.

      Imiquimod also up-regulates IL-2, which down-regulates IL-10, thus reversing the suppression of antitumor Tcells.                                                      

      You can apply the cream to your  face to stimulate the local immune system at the point of contact.  "   

             Best regards,                              

      Jimmy B   

      **********************8     

      I have heard of aldara and I have the following questions about aldara?

      Does aldara work on Subq's (lumps) "beneath" the skin or just "skin" cutaneous based melanoma.

      I have a small lump under my skin but the lump is poking through my skin. Would aldara be effective on my subq lump if I rubbed  aldara into the lump?? There is no melanoma color on the top of the lump…just skin color.

      Thanks for your help.

      Mary

                                                                                         

    Viewing 5 reply threads
    • Replies
        jim Breitfeller
        Participant

          Mary, Imiquimod may work for you. I would suggest that you get approval through your oncologist. It is a prescription cream that you appy to the target area. Some Patients have a violent reaction. Care must be taken while using it. Follow the instructions to a T.

          If your sub Q's are close to the surface, Imiquimod may work.

           

          Take care 

          Jimmy B

           

          jim Breitfeller
          Participant

            Mary, Imiquimod may work for you. I would suggest that you get approval through your oncologist. It is a prescription cream that you appy to the target area. Some Patients have a violent reaction. Care must be taken while using it. Follow the instructions to a T.

            If your sub Q's are close to the surface, Imiquimod may work.

             

            Take care 

            Jimmy B

             

            MichaelFL
            Participant

              Although it has been used for Basal cell, actinic keratosis, and more rarely for some forms of lentigo maligna melanoma, you may wish to discuss with your doctor if you should use this personally for melanoma sub q's. When possible, surgery is the best option, and if I recall correctly, Jim uses it as a follow up post surgery on that area, and he applies it to the primary tumor site every 3 months for about 5 days.

              So, one might consider Imiquimod post surgery, but from my reading, the data is limited on it's effectiveness as well.

              Michael

              MichaelFL
              Participant

                Although it has been used for Basal cell, actinic keratosis, and more rarely for some forms of lentigo maligna melanoma, you may wish to discuss with your doctor if you should use this personally for melanoma sub q's. When possible, surgery is the best option, and if I recall correctly, Jim uses it as a follow up post surgery on that area, and he applies it to the primary tumor site every 3 months for about 5 days.

                So, one might consider Imiquimod post surgery, but from my reading, the data is limited on it's effectiveness as well.

                Michael

                jimjoeb
                Participant

                  I used it very effectively for actinic keratosis before I was diagnosed with melanoma.

                  jimjoeb
                  Participant

                    I used it very effectively for actinic keratosis before I was diagnosed with melanoma.

                Viewing 5 reply threads
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