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Seviprotimut-l side effect?
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Seviprotimut-l side effect?

› Forums › General Melanoma Community › Seviprotimut-l side effect?

  • Post
    • May 2, 2017 at 7:26 pm
    caitybird
    Participant
      I am wondering if anyone out there has been on the seviprotimut-l (pol-103) trial and experienced any side effects. I have 1 more injection to finish my 2 years, have always had skin reaction (my arm looks like a drug addict that doesn’t know what a vein looks like), but I’ve been having chronic stomach/abdominal pain for a year now, nothing helps, also having pressure changes in my head for lack of a better description. Nothing I can find in research mentions side effects beyond injection site; Dr is unconcerned; ct scans show nothing. I’ll mention the Dr is not my original, I moved after starting trial and had to find another study site. The Dr I was assigned was a hematologist but left, my replacement is also a hematologist. Lymphedema specialist says maybe its lymphadema; gastroenterologist says maybe its superficial nerve pain. My next step is demanding endoscopy and colonoscopy. But, I have found articles on other immunotherapies that have caused stomach/colon responses due to basically autoimmune response. I just would like to know if anyone else has had any side effects or if I’m just falling apart.
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        • May 10, 2017 at 9:28 pm
        Boise Steve
        Participant

          Hello there – I completed my 2 year trial in January of this year.  The only side effect was the same as you experienced, skin reactions.  

          I understand that there may be some data/news coming soon from this trial.  I am excited to think that there may be a new therapy for the stage 3 folks (like me).

            • February 6, 2018 at 11:44 pm
            DoubleTT
            Participant
              Hello…I have one more injection April 2018. This drug has it’s side effects like skin issues, flu like symptoms for first 3 to 5 days, constipation, and it threw me into a very quick menopause that was bound to happen but it happened very quickly. I also for the first year had joint and muscle pain that was present all the time. Once the injections were further apart that calmed down. And yes injection marks everywhere. But I don’t care I just hope it works until better meds are available for my stage 3B melanoma with NRAS gene mutation uggh…I was diagnosed and operated on January 2016. I live in Ontario Canada
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