Stage IV
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Stage IV

› Forums › General Melanoma Community › Stage IV

  • Post
    • January 7, 2014 at 1:01 am
    Pathuttenga
    Participant

      My 34 year son was diagnosed two years ago

      large mole on torso surgically removed with lymph nodes under arm, one of 12 nodes infected

      radiation for 6 weeks then 12 months of interferon

      july 2013 MRI showed small brain lesion and 3 new tumors on torso and back

      radiation of total brain for 4 weeks plus 1 mega boost to exact spot

      12 weeks of yervoy

      good news brain MRI showed lesion gone

      bad news tumors on torso 2mm larger and also on liver and spleen and new tumor on thigh and side torso

      next step clinical trial – dr Laos at u of m has already closed his trial so have been recommended us to karmonas cancer at Wayne state

      waiting now for appt date

      Pat

    Viewing 5 reply threads
    • Replies
        • January 7, 2014 at 3:06 am
        BrianP
        Participant

          Pat,

          Sorry for the latest bump in the road.  Has your son looked for PD-1 trials.  Seems like I've seen one or two lately that do allow for prior IPI treatments.  You may try to post on MIF and see if Catherine Poole knows of any.  She's a great resource for the latest and greatest on Nivo trials.  Good luck to you and your son.

          Brian

          • January 7, 2014 at 3:06 am
          BrianP
          Participant

            Pat,

            Sorry for the latest bump in the road.  Has your son looked for PD-1 trials.  Seems like I've seen one or two lately that do allow for prior IPI treatments.  You may try to post on MIF and see if Catherine Poole knows of any.  She's a great resource for the latest and greatest on Nivo trials.  Good luck to you and your son.

            Brian

            • January 7, 2014 at 3:06 am
            BrianP
            Participant

              Pat,

              Sorry for the latest bump in the road.  Has your son looked for PD-1 trials.  Seems like I've seen one or two lately that do allow for prior IPI treatments.  You may try to post on MIF and see if Catherine Poole knows of any.  She's a great resource for the latest and greatest on Nivo trials.  Good luck to you and your son.

              Brian

              • January 7, 2014 at 3:33 am
              POW
              Participant

                There are very few anti-PD1 trials open now. However, a new treatment called anti-PD-L1 is expanding trials and it may be even better than anti-PD1. Catherine Poole at the Melanoma International Foundation just posted this today. 

                Here is a new PDL trial opening very soon: http://clinicaltrials.gov/ct2/show/NCT0 … 736&rank=1



                Locations are listed and there may be more. It is for both BRAF positive and BRAF negative.

                You can't have prior BRAF drugs. But didn't see any other exclusions for prior therapy.
                Catherine M. Poole, President/Founder
                • January 7, 2014 at 3:33 am
                POW
                Participant

                  There are very few anti-PD1 trials open now. However, a new treatment called anti-PD-L1 is expanding trials and it may be even better than anti-PD1. Catherine Poole at the Melanoma International Foundation just posted this today. 

                  Here is a new PDL trial opening very soon: http://clinicaltrials.gov/ct2/show/NCT0 … 736&rank=1



                  Locations are listed and there may be more. It is for both BRAF positive and BRAF negative.

                  You can't have prior BRAF drugs. But didn't see any other exclusions for prior therapy.
                  Catherine M. Poole, President/Founder
                  • January 7, 2014 at 3:33 am
                  POW
                  Participant

                    There are very few anti-PD1 trials open now. However, a new treatment called anti-PD-L1 is expanding trials and it may be even better than anti-PD1. Catherine Poole at the Melanoma International Foundation just posted this today. 

                    Here is a new PDL trial opening very soon: http://clinicaltrials.gov/ct2/show/NCT0 … 736&rank=1



                    Locations are listed and there may be more. It is for both BRAF positive and BRAF negative.

                    You can't have prior BRAF drugs. But didn't see any other exclusions for prior therapy.
                    Catherine M. Poole, President/Founder
                Viewing 5 reply threads

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