Stage IV – Clinical Trial Treatment – Now spot on the brain

I recently left a PD1 trial in favor of surgery. It just wasn't working well enough for me.  Maybe that is the case for you, Ipi just wasn't enough. There is nothing you did that brought the brain met, I also know how devastating that diagnosis can be.  There are lots of stage 4 survivors here including myself, that have dealt with brain mets and are still here fighting. Never give up!!

Amy

I recently left a PD1 trial in favor of surgery. It just wasn't working well enough for me.  Maybe that is the case for you, Ipi just wasn't enough. There is nothing you did that brought the brain met, I also know how devastating that diagnosis can be.  There are lots of stage 4 survivors here including myself, that have dealt with brain mets and are still here fighting. Never give up!!

Amy

I recently left a PD1 trial in favor of surgery. It just wasn't working well enough for me.  Maybe that is the case for you, Ipi just wasn't enough. There is nothing you did that brought the brain met, I also know how devastating that diagnosis can be.  There are lots of stage 4 survivors here including myself, that have dealt with brain mets and are still here fighting. Never give up!!

Amy

Treatment for brain mets has gotten very good!  Here is a link to a really good webinar by Yale neurosurgeon about gamma knife which is what you will be doing.  Once the brain met is zapped and you are stable you can go back on the trial most likely.  Here's the link:  http://melanomainternational.org/webinar/2012/01/radiation-treatment-in-brain-metastases/#.Umw6H_XD_Z4

Treatment for brain mets has gotten very good!  Here is a link to a really good webinar by Yale neurosurgeon about gamma knife which is what you will be doing.  Once the brain met is zapped and you are stable you can go back on the trial most likely.  Here's the link:  http://melanomainternational.org/webinar/2012/01/radiation-treatment-in-brain-metastases/#.Umw6H_XD_Z4

Treatment for brain mets has gotten very good!  Here is a link to a really good webinar by Yale neurosurgeon about gamma knife which is what you will be doing.  Once the brain met is zapped and you are stable you can go back on the trial most likely.  Here's the link:  http://melanomainternational.org/webinar/2012/01/radiation-treatment-in-brain-metastases/#.Umw6H_XD_Z4

Hello,

I am so sorry to hear about your brain met but as other have stated many have survived having SRS or gama knife to zap brain mets.

Who is the sponsor of your trial? Is it BMS?

You mentioned "the spot on the brain could disqualify me from the trial", did your onc tell you that you will be kicked off the trial??? If you have the brain met radiated, would you be kicked off the trial??

I am trying to learn what is allowed on these clinical trials, so it would be helpful if any one can tell me if you get a brain met, you automatically get kicked of a trial?

Thanks for replying to my post.

Bertha

Hello,

I am so sorry to hear about your brain met but as other have stated many have survived having SRS or gama knife to zap brain mets.

Who is the sponsor of your trial? Is it BMS?

You mentioned "the spot on the brain could disqualify me from the trial", did your onc tell you that you will be kicked off the trial??? If you have the brain met radiated, would you be kicked off the trial??

I am trying to learn what is allowed on these clinical trials, so it would be helpful if any one can tell me if you get a brain met, you automatically get kicked of a trial?

Thanks for replying to my post.

Bertha

Hello,

I am so sorry to hear about your brain met but as other have stated many have survived having SRS or gama knife to zap brain mets.

Who is the sponsor of your trial? Is it BMS?

You mentioned "the spot on the brain could disqualify me from the trial", did your onc tell you that you will be kicked off the trial??? If you have the brain met radiated, would you be kicked off the trial??

I am trying to learn what is allowed on these clinical trials, so it would be helpful if any one can tell me if you get a brain met, you automatically get kicked of a trial?

Thanks for replying to my post.

Bertha

Did you end up doing Radiostatic/Cyber knife (bunch of different names used) surgery to remove the brain tumor?   The stats on the effectiveness are very high.   If you can remove it can you reenter what looks to be a great trial?  Although I just had brain tumor surgically removed the pathology showed 90% dead so it did see some benefit from prior radiation and yervoy combo.   Currently ned and doing followup radiostatic to clean up any stray cells and combining with more yervoy.   Anti pd1 was my first choice but brain tumor had shut me out. Yervoy and radiation not a bad second option.  Good luck.  

Did you end up doing Radiostatic/Cyber knife (bunch of different names used) surgery to remove the brain tumor?   The stats on the effectiveness are very high.   If you can remove it can you reenter what looks to be a great trial?  Although I just had brain tumor surgically removed the pathology showed 90% dead so it did see some benefit from prior radiation and yervoy combo.   Currently ned and doing followup radiostatic to clean up any stray cells and combining with more yervoy.   Anti pd1 was my first choice but brain tumor had shut me out. Yervoy and radiation not a bad second option.  Good luck.  

Did you end up doing Radiostatic/Cyber knife (bunch of different names used) surgery to remove the brain tumor?   The stats on the effectiveness are very high.   If you can remove it can you reenter what looks to be a great trial?  Although I just had brain tumor surgically removed the pathology showed 90% dead so it did see some benefit from prior radiation and yervoy combo.   Currently ned and doing followup radiostatic to clean up any stray cells and combining with more yervoy.   Anti pd1 was my first choice but brain tumor had shut me out. Yervoy and radiation not a bad second option.  Good luck.