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stage iv with brain mets- question about symptoms

Forums General Melanoma Community stage iv with brain mets- question about symptoms

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    Holliesig
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      My dad is currently stage IV with 6 brain mets, originally treated with SRS and then 1 round of IPI/NIV before being hospitalized for swelling of the brain in early January. He was put on high dose steroids and now on mekinist and trametinib for 2 months. At first he felt awful from the chemo, but has been feeling pretty decent for about a month now. He had an MRI 2 weeks ago that showed reduction in the 3 largest tumors and no further progression of the smaller tumors or new tumors. We have been slowly tapering the steroids over the past 3-4 weeks without issues so far. Over the weekend, he started feeling extreme exhaustion, nausea, and fever with chills and then sweats. Went into doc yesterday for labs, labs looked normal. He got an antibiotic in case he was coming down with something. He feels worse today, nausea- no appetite- continued fever close to hovering around 101.7 and hasn't gotten out of bed. This seems odd to me after being stable on the chemo and the tapering of the steroids being so gradual.. He's not achy so it doesnt seem like it would be the flu to me. Does anyone have any advice or experience with anything similar? I'm his primary caretaker and starting to worry about something more serious going on. 

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