I had Stage IIIB Amelanotic nodular melanoma and was NED for 7 months. I went into see Derm in December and pointed ot two spots on my leg that concerened me. After biopsy, it was found that I have in-transit melanoma which moved me to Stage IIIC. By January I had 7 lesions and by February and my first set of T-VEC injections, I had over 30 lesions.
Started T-VEC injections in February with only 7 injections. After waiting 3 weeks for next injections, doctor decided that I needed 20 injections because of all of the melanoma lesions that have popped up on my thigh. The 20 injections didn't hurt really because I have no feeling in my thigh from prior surgery, but the side effects afterwards were not fun. Within three hours of the injections, I was shaking uncontrolably, running a high fever and vomiting. I was not able to hold down any solid food for three days. I was worn out and sore for the rest of that week and finally got back to normal a week later. This time, I had 20 injections and I didn't even make it home before the shakes started. It was quite scary driving myself home like that, but I made it safely. Again, high fever, vomiting, and shakes but this only lasted over night and today I'm a bit wornn out, but not as bas as I was with the first 20 injections.
The next time I go in, the doctor wants to do 30 injections. I am not looking forward to that at all, but at this point, I don't know what else to do. I have a new melanoma lesion pop up on my leg daily, it seems. Some have even come together to form one big one. I am just afraid with the waiting for them to be big enough to inject and watching them get so big (even bigger than originl melanoma) that it will end up spreading and I will become stage IV.
I just feel like I am not doing enough to become NED from this disease. Any advice would be greatly appreciated.
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