› Forums › General Melanoma Community › Treatment and Next Steps – Combo Ipi/Nivo
- This topic has 9 replies, 3 voices, and was last updated 10 years, 3 months ago by
michael1212.
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- February 12, 2015 at 12:31 am
Hello. My wife was just diagnosed with a nodule on her lung from the CAT scan (October had a clean PET scan, and surgery for full lymph node dissection in November). The dcotors are going to do a biopsy of the nodule next week but we are assuming it is melanoma until we hear otherwise (versus an infection, inflammation). She has spoken to the melanoma oncologist and has agreed to a clinical trial with an Ipi (3mg) and Nivo (1mg) combination for 12 weeks, concurrent doses given every 3 weeks for 4 cycles. After the 12 weeks she would get Nivo (3mg) every 2 weeks for some time. She is BRAF negative.
Does anyone have any advice with this? I know of the multiple and significant symptoms but she seems determined to move forward with this treatment and try to get through the 12 weeks program combo program. She has discussed medicines to manage the side effects with the doctors. I have heard that Nivo (or Keytruda) is more manageable in terms of side effects versus Ipi if she is able to get past the 12 weeks concurrent regimen.
Thanks,
Michael1212
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- February 12, 2015 at 4:55 am
Hi Michael, I am sorry to hear you and your wife are going through this. It sounds like she is in a trial like I am about to start at Hopkins. I truly this works for her, as I am also hoping it works for me! I did post on this board recently asking about the side effects and thoughts on the trial in general. I had some very positive responses, and it seems that the best advice I received was to stay on top of the side effects. Meaning, as soon as she starts to experience a side effect to let her doctor know so they can combat the side effect before it gets worse. If you go to my profile on here you can see all of my posts, and read the very helpful responses I received. I hope this helps you. Best wishes!!
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- February 12, 2015 at 4:55 am
Hi Michael, I am sorry to hear you and your wife are going through this. It sounds like she is in a trial like I am about to start at Hopkins. I truly this works for her, as I am also hoping it works for me! I did post on this board recently asking about the side effects and thoughts on the trial in general. I had some very positive responses, and it seems that the best advice I received was to stay on top of the side effects. Meaning, as soon as she starts to experience a side effect to let her doctor know so they can combat the side effect before it gets worse. If you go to my profile on here you can see all of my posts, and read the very helpful responses I received. I hope this helps you. Best wishes!!
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- February 12, 2015 at 4:55 am
Hi Michael, I am sorry to hear you and your wife are going through this. It sounds like she is in a trial like I am about to start at Hopkins. I truly this works for her, as I am also hoping it works for me! I did post on this board recently asking about the side effects and thoughts on the trial in general. I had some very positive responses, and it seems that the best advice I received was to stay on top of the side effects. Meaning, as soon as she starts to experience a side effect to let her doctor know so they can combat the side effect before it gets worse. If you go to my profile on here you can see all of my posts, and read the very helpful responses I received. I hope this helps you. Best wishes!!
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- February 12, 2015 at 7:05 pm
Here are a couple posts regarding the ipi/nivo combo that you might find helpful:
Here is another that addresses the side effects most commonly encounter by folks on Nivo:
http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2013/10/side-effects-of-nivolumab.html
I wish you and your wife my best. Celeste
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- February 12, 2015 at 7:05 pm
Here are a couple posts regarding the ipi/nivo combo that you might find helpful:
Here is another that addresses the side effects most commonly encounter by folks on Nivo:
http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2013/10/side-effects-of-nivolumab.html
I wish you and your wife my best. Celeste
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- February 12, 2015 at 7:05 pm
Here are a couple posts regarding the ipi/nivo combo that you might find helpful:
Here is another that addresses the side effects most commonly encounter by folks on Nivo:
http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2013/10/side-effects-of-nivolumab.html
I wish you and your wife my best. Celeste
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