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Whole Leg Perfusion

Forums General Melanoma Community Whole Leg Perfusion

  • Post
    marysan
    Participant

      Has anyone done whole leg perfusion?  Can anyone recommend a teaching facility in the NE that has had success with this?  My husband has Stage 3C melanoma, started with the 4th toe with two recurrences over the past year on the lower leg.  Thanks for any information.

      Has anyone done whole leg perfusion?  Can anyone recommend a teaching facility in the NE that has had success with this?  My husband has Stage 3C melanoma, started with the 4th toe with two recurrences over the past year on the lower leg.  Thanks for any information.

    Viewing 11 reply threads
    • Replies
        SoCalDave
        Participant

          They talked about it with me – same stage as your husband with more re-ocurrences than I care to count. I'm seeing good docs here in So Cal but they said if I opted for it I'd have to go to MD Anderson.

          David

            killmel
            Participant

              Hi Dave,

               

              It was great to so your post. How are you doing?? Are you still having  treatment?

               

              Wishing you well always,

               

              Amy

              SoCalDave
              Participant

                Hi Amy, doing okay. Still have the occasional mel appear but always in the same general area (left ankle). Had an eight month period where none came back which really got my hopes up, but then 2 came back last month. Still using the DPCP on a weekly basis.

                To the original poster, my docs really scared me off the perfusion. Possible loss of leg, etc. Not something I would have done unless it was my only option. Don't know if DPCP would work in your case or not. Here's some info on DPCP:

                http://www.australiancancertrials.gov.au/search-clinical-trials/search-results/clinical-trials-details.aspx?TrialID=308033&ds=1

                I'm not in that trial (I'm in California) but one of my docs had attended a symposium in Austrailia and suggested we give it a try on our own.

                Thanks for asking!

                Dave

                SoCalDave
                Participant

                  Hi Amy, doing okay. Still have the occasional mel appear but always in the same general area (left ankle). Had an eight month period where none came back which really got my hopes up, but then 2 came back last month. Still using the DPCP on a weekly basis.

                  To the original poster, my docs really scared me off the perfusion. Possible loss of leg, etc. Not something I would have done unless it was my only option. Don't know if DPCP would work in your case or not. Here's some info on DPCP:

                  http://www.australiancancertrials.gov.au/search-clinical-trials/search-results/clinical-trials-details.aspx?TrialID=308033&ds=1

                  I'm not in that trial (I'm in California) but one of my docs had attended a symposium in Austrailia and suggested we give it a try on our own.

                  Thanks for asking!

                  Dave

                  SoCalDave
                  Participant

                    Hi Amy, doing okay. Still have the occasional mel appear but always in the same general area (left ankle). Had an eight month period where none came back which really got my hopes up, but then 2 came back last month. Still using the DPCP on a weekly basis.

                    To the original poster, my docs really scared me off the perfusion. Possible loss of leg, etc. Not something I would have done unless it was my only option. Don't know if DPCP would work in your case or not. Here's some info on DPCP:

                    http://www.australiancancertrials.gov.au/search-clinical-trials/search-results/clinical-trials-details.aspx?TrialID=308033&ds=1

                    I'm not in that trial (I'm in California) but one of my docs had attended a symposium in Austrailia and suggested we give it a try on our own.

                    Thanks for asking!

                    Dave

                    killmel
                    Participant

                      Hi Dave,

                       

                      It was great to so your post. How are you doing?? Are you still having  treatment?

                       

                      Wishing you well always,

                       

                      Amy

                      killmel
                      Participant

                        Hi Dave,

                         

                        It was great to so your post. How are you doing?? Are you still having  treatment?

                         

                        Wishing you well always,

                         

                        Amy

                        marysan
                        Participant

                           

                          Dave,

                           

                          Thanks for the information. My husband has lymphedema in the leg…so I was not sure if he would be a candidate. Will look into program at MD Anderson. I am interested in the topical cream you are using. Are your recurrences subcutaneous or at the skin surface?  I appreciate your help.

                          SoCalDave
                          Participant

                            My recurrences have all been new mels on the skin surface, just like new, very small moles popping up. No subqs. I've already had a large chunk of the calf taken out – about 4 inches by inches – with skin graft, complete lymph node dissection but then they still came back but all local to the original site. Docs think we'll just treat it as a chronic condition and keep using the dpcp and slicing and dicing if they keep appearing.

                            Dave

                            SoCalDave
                            Participant

                              My recurrences have all been new mels on the skin surface, just like new, very small moles popping up. No subqs. I've already had a large chunk of the calf taken out – about 4 inches by inches – with skin graft, complete lymph node dissection but then they still came back but all local to the original site. Docs think we'll just treat it as a chronic condition and keep using the dpcp and slicing and dicing if they keep appearing.

                              Dave

                              SoCalDave
                              Participant

                                My recurrences have all been new mels on the skin surface, just like new, very small moles popping up. No subqs. I've already had a large chunk of the calf taken out – about 4 inches by inches – with skin graft, complete lymph node dissection but then they still came back but all local to the original site. Docs think we'll just treat it as a chronic condition and keep using the dpcp and slicing and dicing if they keep appearing.

                                Dave

                                marysan
                                Participant

                                   

                                  Dave,

                                   

                                  Thanks for the information. My husband has lymphedema in the leg…so I was not sure if he would be a candidate. Will look into program at MD Anderson. I am interested in the topical cream you are using. Are your recurrences subcutaneous or at the skin surface?  I appreciate your help.

                                  marysan
                                  Participant

                                     

                                    Dave,

                                     

                                    Thanks for the information. My husband has lymphedema in the leg…so I was not sure if he would be a candidate. Will look into program at MD Anderson. I am interested in the topical cream you are using. Are your recurrences subcutaneous or at the skin surface?  I appreciate your help.

                                  SoCalDave
                                  Participant

                                    They talked about it with me – same stage as your husband with more re-ocurrences than I care to count. I'm seeing good docs here in So Cal but they said if I opted for it I'd have to go to MD Anderson.

                                    David

                                    SoCalDave
                                    Participant

                                      They talked about it with me – same stage as your husband with more re-ocurrences than I care to count. I'm seeing good docs here in So Cal but they said if I opted for it I'd have to go to MD Anderson.

                                      David

                                      King
                                      Participant

                                        I'm quite certain that DonnaVT had this done at Mass General a couple of years ago.  She is a frequent poster here and hopefully she will see this and be able to give you more information.

                                        Stay Strong

                                        King

                                        Stage IV  7/05  Liver Mets

                                          Vermont_Donna
                                          Participant

                                            Thanks King…yes I did have an "Isloated Limb Perfusion" done in September 2009 at Mass General in Boston. I dont remember alot of the details so please look at my profile and also put Isolated limb perfusion in the search feature on this board and it will bring up any posts I or others have made. I have leg lymphadema now and I do think I had it before the ILP also. The procedure is about 85% effective, but for me, my melanoma re-occurred about 11 months later I believe. Yervoy is what I have done most recenly (18 months ago) and I am NED since then.

                                            There is also an isolated limb INFUSION (ILI) that you can look into…..there are several hospitals that do either or both, yes MD Anderson is one, but others more local to NE as well. Your oncologist should be able to help you find out more and what places are doing these procedures.

                                            Please contact me if you need any more assistance or have further questions.

                                            Vermont_Donna, stage 3a, NED 18 months

                                            Vermont_Donna
                                            Participant

                                              Thanks King…yes I did have an "Isloated Limb Perfusion" done in September 2009 at Mass General in Boston. I dont remember alot of the details so please look at my profile and also put Isolated limb perfusion in the search feature on this board and it will bring up any posts I or others have made. I have leg lymphadema now and I do think I had it before the ILP also. The procedure is about 85% effective, but for me, my melanoma re-occurred about 11 months later I believe. Yervoy is what I have done most recenly (18 months ago) and I am NED since then.

                                              There is also an isolated limb INFUSION (ILI) that you can look into…..there are several hospitals that do either or both, yes MD Anderson is one, but others more local to NE as well. Your oncologist should be able to help you find out more and what places are doing these procedures.

                                              Please contact me if you need any more assistance or have further questions.

                                              Vermont_Donna, stage 3a, NED 18 months

                                              Vermont_Donna
                                              Participant

                                                Thanks King…yes I did have an "Isloated Limb Perfusion" done in September 2009 at Mass General in Boston. I dont remember alot of the details so please look at my profile and also put Isolated limb perfusion in the search feature on this board and it will bring up any posts I or others have made. I have leg lymphadema now and I do think I had it before the ILP also. The procedure is about 85% effective, but for me, my melanoma re-occurred about 11 months later I believe. Yervoy is what I have done most recenly (18 months ago) and I am NED since then.

                                                There is also an isolated limb INFUSION (ILI) that you can look into…..there are several hospitals that do either or both, yes MD Anderson is one, but others more local to NE as well. Your oncologist should be able to help you find out more and what places are doing these procedures.

                                                Please contact me if you need any more assistance or have further questions.

                                                Vermont_Donna, stage 3a, NED 18 months

                                              King
                                              Participant

                                                I'm quite certain that DonnaVT had this done at Mass General a couple of years ago.  She is a frequent poster here and hopefully she will see this and be able to give you more information.

                                                Stay Strong

                                                King

                                                Stage IV  7/05  Liver Mets

                                                King
                                                Participant

                                                  I'm quite certain that DonnaVT had this done at Mass General a couple of years ago.  She is a frequent poster here and hopefully she will see this and be able to give you more information.

                                                  Stay Strong

                                                  King

                                                  Stage IV  7/05  Liver Mets

                                                  cwu
                                                  Participant
                                                    Hi,

                                                    We did look into leg perfusion for my dad when his in transit mets climb up all over his right calf but we decided against it. From what I know, it is a very complicated procedure with long recovery and only a few places can perform (MDAnderson in Houston). Dad is his 80s so we thought the surgery would be too much. Have you looked into other treatment options like Yervoy or Zeboralf or ckit inhibitor like Gleevac? My dad was also stage 3c and he did Yervoy and has partial response, some of his lesions have gotten better, others have gotten worse but it seems like it’s keeping new ones from going up higher on his leg and organs. I too looked into DPCP for him but his lesions were too many and too thick. I emailed a picture of dads leg to the trial doctor for DPCP and she told me he had too many lesions. You should email her, she is very kind and helpful.

                                                    Chau

                                                    cwu
                                                    Participant
                                                      Hi,

                                                      We did look into leg perfusion for my dad when his in transit mets climb up all over his right calf but we decided against it. From what I know, it is a very complicated procedure with long recovery and only a few places can perform (MDAnderson in Houston). Dad is his 80s so we thought the surgery would be too much. Have you looked into other treatment options like Yervoy or Zeboralf or ckit inhibitor like Gleevac? My dad was also stage 3c and he did Yervoy and has partial response, some of his lesions have gotten better, others have gotten worse but it seems like it’s keeping new ones from going up higher on his leg and organs. I too looked into DPCP for him but his lesions were too many and too thick. I emailed a picture of dads leg to the trial doctor for DPCP and she told me he had too many lesions. You should email her, she is very kind and helpful.

                                                      Chau

                                                      cwu
                                                      Participant
                                                        Hi,

                                                        We did look into leg perfusion for my dad when his in transit mets climb up all over his right calf but we decided against it. From what I know, it is a very complicated procedure with long recovery and only a few places can perform (MDAnderson in Houston). Dad is his 80s so we thought the surgery would be too much. Have you looked into other treatment options like Yervoy or Zeboralf or ckit inhibitor like Gleevac? My dad was also stage 3c and he did Yervoy and has partial response, some of his lesions have gotten better, others have gotten worse but it seems like it’s keeping new ones from going up higher on his leg and organs. I too looked into DPCP for him but his lesions were too many and too thick. I emailed a picture of dads leg to the trial doctor for DPCP and she told me he had too many lesions. You should email her, she is very kind and helpful.

                                                        Chau

                                                        Melanoma Warrior
                                                        Participant

                                                          YES, I had a whole leg perfusion last April 15, 2011 

                                                          To date presenting cancer free .. next check-up in October (6mos.) 

                                                          Procedure was not easy… pretty barbaric 

                                                          Was at California Pacific Medical  San Francisco 

                                                          San Francisco doctors were wonderful … 

                                                          My Oncologist Dr. David Minor was very compasionate as was the rest of the team 

                                                           

                                                          The melanoma was on the bottom of my foot and spreading up my shin..

                                                          I was diagnosed with Stage 3B w/ massastisis 

                                                          My dermatologist continuelly reminds me of how lucky I am to be alive..

                                                           

                                                          Side affects : From not moving due to swelling my knee joint froze ….  However I'm alive…

                                                          Melanoma Warrior
                                                          Participant

                                                            YES, I had a whole leg perfusion last April 15, 2011 

                                                            To date presenting cancer free .. next check-up in October (6mos.) 

                                                            Procedure was not easy… pretty barbaric 

                                                            Was at California Pacific Medical  San Francisco 

                                                            San Francisco doctors were wonderful … 

                                                            My Oncologist Dr. David Minor was very compasionate as was the rest of the team 

                                                             

                                                            The melanoma was on the bottom of my foot and spreading up my shin..

                                                            I was diagnosed with Stage 3B w/ massastisis 

                                                            My dermatologist continuelly reminds me of how lucky I am to be alive..

                                                             

                                                            Side affects : From not moving due to swelling my knee joint froze ….  However I'm alive…

                                                            Melanoma Warrior
                                                            Participant

                                                              YES, I had a whole leg perfusion last April 15, 2011 

                                                              To date presenting cancer free .. next check-up in October (6mos.) 

                                                              Procedure was not easy… pretty barbaric 

                                                              Was at California Pacific Medical  San Francisco 

                                                              San Francisco doctors were wonderful … 

                                                              My Oncologist Dr. David Minor was very compasionate as was the rest of the team 

                                                               

                                                              The melanoma was on the bottom of my foot and spreading up my shin..

                                                              I was diagnosed with Stage 3B w/ massastisis 

                                                              My dermatologist continuelly reminds me of how lucky I am to be alive..

                                                               

                                                              Side affects : From not moving due to swelling my knee joint froze ….  However I'm alive…

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