Yervoy

Sorry to hear about the diagnosis, but it is definitely not too late!  There is hope!  I had a 6 cm tumor blocking my entire lung three years ago.  It's been gone for two years after Zelboraf and yervoy with only a subcutaneous reoccurance in my ribcage from a drainage tube biopsy (surgically removed the tumor).  I am grateful that I have the BRaf mutation as the zelboraf worked magic for me.  I did I have swelling in different parts of my body similar to your description while on yervoy and it was scary, but they went away.  I know that with the yervoy things flare up and get worse before they get better.  Hopefully something similar may be happening in your mom's case.  In any event, I would guess there are lots of further options for her – not a lot of fun, but very hopeful!  I'm still here and I wasn't expected to make it a year!  There is hope!

Sorry to hear about the diagnosis, but it is definitely not too late!  There is hope!  I had a 6 cm tumor blocking my entire lung three years ago.  It's been gone for two years after Zelboraf and yervoy with only a subcutaneous reoccurance in my ribcage from a drainage tube biopsy (surgically removed the tumor).  I am grateful that I have the BRaf mutation as the zelboraf worked magic for me.  I did I have swelling in different parts of my body similar to your description while on yervoy and it was scary, but they went away.  I know that with the yervoy things flare up and get worse before they get better.  Hopefully something similar may be happening in your mom's case.  In any event, I would guess there are lots of further options for her – not a lot of fun, but very hopeful!  I'm still here and I wasn't expected to make it a year!  There is hope!

Sorry to hear about the diagnosis, but it is definitely not too late!  There is hope!  I had a 6 cm tumor blocking my entire lung three years ago.  It's been gone for two years after Zelboraf and yervoy with only a subcutaneous reoccurance in my ribcage from a drainage tube biopsy (surgically removed the tumor).  I am grateful that I have the BRaf mutation as the zelboraf worked magic for me.  I did I have swelling in different parts of my body similar to your description while on yervoy and it was scary, but they went away.  I know that with the yervoy things flare up and get worse before they get better.  Hopefully something similar may be happening in your mom's case.  In any event, I would guess there are lots of further options for her – not a lot of fun, but very hopeful!  I'm still here and I wasn't expected to make it a year!  There is hope!

Sounds like she hasn't started yervoy yet. Also without scans it is too early to say what is causing the swelling. Such swelling can be caused by many things. However that is what friends tried to tell me when literally over night the tumor in my collar went from unseen to the size of a small fist. Plus there was some swelling in the side of my neck that went away after a few days. The docs didn't believe me but yes it was overnight. Also that was when they were keeping me on the taf mek combo until I could get into Mercks Eap of pd1. Oh by the way that was late April so as long as you can keep her nutrition and spirit up she can kick this stuff in the rear too. Definitely no where near too late. That tumor in my collar is still the size of a small fist and is one of the 3 tumors still growing. But I have about 27 shrinking. 

So yeah it could be nothing serious. She has definitely received fantastic results already. Even if this is not melanoma spreading you might want to consider an immunotherapy like yervoy then pd1 to get that long lasting response going. But that is just my opinion.

Artie

Sounds like she hasn't started yervoy yet. Also without scans it is too early to say what is causing the swelling. Such swelling can be caused by many things. However that is what friends tried to tell me when literally over night the tumor in my collar went from unseen to the size of a small fist. Plus there was some swelling in the side of my neck that went away after a few days. The docs didn't believe me but yes it was overnight. Also that was when they were keeping me on the taf mek combo until I could get into Mercks Eap of pd1. Oh by the way that was late April so as long as you can keep her nutrition and spirit up she can kick this stuff in the rear too. Definitely no where near too late. That tumor in my collar is still the size of a small fist and is one of the 3 tumors still growing. But I have about 27 shrinking. 

So yeah it could be nothing serious. She has definitely received fantastic results already. Even if this is not melanoma spreading you might want to consider an immunotherapy like yervoy then pd1 to get that long lasting response going. But that is just my opinion.

Artie

Sounds like she hasn't started yervoy yet. Also without scans it is too early to say what is causing the swelling. Such swelling can be caused by many things. However that is what friends tried to tell me when literally over night the tumor in my collar went from unseen to the size of a small fist. Plus there was some swelling in the side of my neck that went away after a few days. The docs didn't believe me but yes it was overnight. Also that was when they were keeping me on the taf mek combo until I could get into Mercks Eap of pd1. Oh by the way that was late April so as long as you can keep her nutrition and spirit up she can kick this stuff in the rear too. Definitely no where near too late. That tumor in my collar is still the size of a small fist and is one of the 3 tumors still growing. But I have about 27 shrinking. 

So yeah it could be nothing serious. She has definitely received fantastic results already. Even if this is not melanoma spreading you might want to consider an immunotherapy like yervoy then pd1 to get that long lasting response going. But that is just my opinion.

Artie

Given the great–and very recent–results your mom has had on the combo, it seems unlikely that things would turn so rapidly.  Easier said than done, but try to keep your head (and hers) in check.  Raise with your mom's onc and she if re-scans earlier in the cycle are appropriate.

Given the great–and very recent–results your mom has had on the combo, it seems unlikely that things would turn so rapidly.  Easier said than done, but try to keep your head (and hers) in check.  Raise with your mom's onc and she if re-scans earlier in the cycle are appropriate.

Given the great–and very recent–results your mom has had on the combo, it seems unlikely that things would turn so rapidly.  Easier said than done, but try to keep your head (and hers) in check.  Raise with your mom's onc and she if re-scans earlier in the cycle are appropriate.