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Yervoy failed and now in his stomach
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Yervoy failed and now in his stomach

› Forums › Cutaneous Melanoma Community › Yervoy failed and now in his stomach

  • Post
    • June 19, 2015 at 12:27 am
    Mom2Addy
    Participant

      My husband had SRS on two brain mets in Jan, surgery to remove 5 subcutaneous nodules and four treatments of Yervoy. His PET scan two weeks ago showed two additional nodules and something in his stomach. He had an endoscopy last Friday and a 24mm nodule removed which we found out today was positive for melanoma. Has anyone else had it in the stomach and if so, what course of treatment did you follow? Yes, we are with a melanoma specialist but won't see him until the week. He's also BRAF positive. Thank you! 

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        • June 19, 2015 at 11:08 am
        Bubbles
        Participant

          Sorry for this progression. I have not personally experienced this, but metastasis to the gut is sadly not uncommon with melanoma. Surgery can often be helpful, followed by an anti-PD1product. Sometimes BRAFi combined with MEKi can be used to rapidly shrink the tumor to the follow-up with a less invasive surgery or then simply shift to anti-PD1 after the tumors are decreased. Additionally, more and more folks are proving that combination BRAFi products, with alternative dosing schedules, are successfully using these products far longer than the 6-9 month duration that used to be the norm. I don't know which of these scenarios would be best for your husband….but these are the ones I would ask about. Wishing you my best. Celeste

          • June 19, 2015 at 11:08 am
          Bubbles
          Participant

            Sorry for this progression. I have not personally experienced this, but metastasis to the gut is sadly not uncommon with melanoma. Surgery can often be helpful, followed by an anti-PD1product. Sometimes BRAFi combined with MEKi can be used to rapidly shrink the tumor to the follow-up with a less invasive surgery or then simply shift to anti-PD1 after the tumors are decreased. Additionally, more and more folks are proving that combination BRAFi products, with alternative dosing schedules, are successfully using these products far longer than the 6-9 month duration that used to be the norm. I don't know which of these scenarios would be best for your husband….but these are the ones I would ask about. Wishing you my best. Celeste

            • June 19, 2015 at 11:08 am
            Bubbles
            Participant

              Sorry for this progression. I have not personally experienced this, but metastasis to the gut is sadly not uncommon with melanoma. Surgery can often be helpful, followed by an anti-PD1product. Sometimes BRAFi combined with MEKi can be used to rapidly shrink the tumor to the follow-up with a less invasive surgery or then simply shift to anti-PD1 after the tumors are decreased. Additionally, more and more folks are proving that combination BRAFi products, with alternative dosing schedules, are successfully using these products far longer than the 6-9 month duration that used to be the norm. I don't know which of these scenarios would be best for your husband….but these are the ones I would ask about. Wishing you my best. Celeste

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