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zelboraf not working what next?
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zelboraf not working what next?

› Forums › Cutaneous Melanoma Community › zelboraf not working what next?

  • Post
    • November 1, 2012 at 7:13 am
    doriniel
    Participant

      So just had my 6 month ct i have been off and on zelboraf for 15 months. I now have a subcutaneous tumor that has grown in size. I have only been taking zelboraf half strength due to side affects and only one week one and one week off. So here is my dilemma do i increase the dose and take it steady and suffer through the side effects (terrible feet and joint been, low energy, nausea) and give the zelboraf another go? Or do I switch to yervoy. or do I join a new clinical trail ( if any are available) any ideas.

      So just had my 6 month ct i have been off and on zelboraf for 15 months. I now have a subcutaneous tumor that has grown in size. I have only been taking zelboraf half strength due to side affects and only one week one and one week off. So here is my dilemma do i increase the dose and take it steady and suffer through the side effects (terrible feet and joint been, low energy, nausea) and give the zelboraf another go? Or do I switch to yervoy. or do I join a new clinical trail ( if any are available) any ideas. all other tumors are gone or are littler than previous only have the one that tripled in size.

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        • November 1, 2012 at 10:28 pm
        POW
        Participant

          For some unknown reason, while Zelboraf does kill malignant melanoma it also stimulates the other 2 types of skin cancer– basal cell and squamous cell carcinoma. Has your subcutaneous tumor been biopsied? What type is it? 

          • November 1, 2012 at 10:28 pm
          POW
          Participant

            For some unknown reason, while Zelboraf does kill malignant melanoma it also stimulates the other 2 types of skin cancer– basal cell and squamous cell carcinoma. Has your subcutaneous tumor been biopsied? What type is it? 

              • November 2, 2012 at 4:18 am
              doriniel
              Participant

                yes it has been biopsied. Came back metastatic melanoma, bummer. I have gone back on Zelboraf 3 pills twice a day going to give it a month and see if the tumor gets bigger will have to do something different.

                • November 2, 2012 at 4:18 am
                doriniel
                Participant

                  yes it has been biopsied. Came back metastatic melanoma, bummer. I have gone back on Zelboraf 3 pills twice a day going to give it a month and see if the tumor gets bigger will have to do something different.

                  • November 2, 2012 at 4:18 am
                  doriniel
                  Participant

                    yes it has been biopsied. Came back metastatic melanoma, bummer. I have gone back on Zelboraf 3 pills twice a day going to give it a month and see if the tumor gets bigger will have to do something different.

                  • November 1, 2012 at 10:28 pm
                  POW
                  Participant

                    For some unknown reason, while Zelboraf does kill malignant melanoma it also stimulates the other 2 types of skin cancer– basal cell and squamous cell carcinoma. Has your subcutaneous tumor been biopsied? What type is it? 

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