MRF-Logo2019-Horizontal-RGB
Zelboraf Side Effects
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Zelboraf Side Effects

› Forums › General Melanoma Community › Zelboraf Side Effects

  • Post
    • March 5, 2012 at 3:48 pm
    Kellie-T
    Participant

      For those that are taking Zelboraf; I'm experiencing joint pain which seems to come and go (changes from left wrist/hand to right wrist/hand and left shoulder/right shoulder). I'm also getting a sore throat which also changes from left to right. Pain in my heels also but that was expected. I also run a low fever sometimes. I started 8 pills a day on the 14th of February but stopped on the 21st due to extreme side effects (face swelled and developed terrible rash). The doc reduced the dose and I started back on the 24th of February at 6 pills a day.

      For those that are taking Zelboraf; I'm experiencing joint pain which seems to come and go (changes from left wrist/hand to right wrist/hand and left shoulder/right shoulder). I'm also getting a sore throat which also changes from left to right. Pain in my heels also but that was expected. I also run a low fever sometimes. I started 8 pills a day on the 14th of February but stopped on the 21st due to extreme side effects (face swelled and developed terrible rash). The doc reduced the dose and I started back on the 24th of February at 6 pills a day.

      Have any of you experienced any of these side effects? Did you take any OTC's to help with it?

       

      Thanks,

      Kellie

    Viewing 8 reply threads
    • Replies
        • March 5, 2012 at 10:05 pm
        deardad
        Participant

          Hi Kellie, I am not the patient but my father has been on this drug for 7 months and has had the same joint pain you are describing. He is also on the maximum dose of 8 pills a day. He also had a sore throat for awhile but that has subsided now. The only pain relief he has is neurophen. Unfortunately he is still having joint pain, hair loss and rash (not as severe as yours) but we are grateful this drug is working. Take care and hope your symptoms settle.

          Nahmi 

          • March 5, 2012 at 10:05 pm
          deardad
          Participant

            Hi Kellie, I am not the patient but my father has been on this drug for 7 months and has had the same joint pain you are describing. He is also on the maximum dose of 8 pills a day. He also had a sore throat for awhile but that has subsided now. The only pain relief he has is neurophen. Unfortunately he is still having joint pain, hair loss and rash (not as severe as yours) but we are grateful this drug is working. Take care and hope your symptoms settle.

            Nahmi 

            • March 5, 2012 at 10:05 pm
            deardad
            Participant

              Hi Kellie, I am not the patient but my father has been on this drug for 7 months and has had the same joint pain you are describing. He is also on the maximum dose of 8 pills a day. He also had a sore throat for awhile but that has subsided now. The only pain relief he has is neurophen. Unfortunately he is still having joint pain, hair loss and rash (not as severe as yours) but we are grateful this drug is working. Take care and hope your symptoms settle.

              Nahmi 

              • March 6, 2012 at 1:31 am
              jmmm
              Participant
                My husband has been on Zelboraf for 4 months. His side effects have been come and go joint pain, hair loss, fever (up to 103), chills, come and go rash, and now red eyes. He’s on a reduced dose (6 pills a day) and the side effects are much better. He’s doesn’t take any OTC meds…his liver levels seem to go up whenever he adds any other meds in. Check with your doctor before starting anything.
                • March 6, 2012 at 1:31 am
                jmmm
                Participant
                  My husband has been on Zelboraf for 4 months. His side effects have been come and go joint pain, hair loss, fever (up to 103), chills, come and go rash, and now red eyes. He’s on a reduced dose (6 pills a day) and the side effects are much better. He’s doesn’t take any OTC meds…his liver levels seem to go up whenever he adds any other meds in. Check with your doctor before starting anything.
                  • March 6, 2012 at 1:31 am
                  jmmm
                  Participant
                    My husband has been on Zelboraf for 4 months. His side effects have been come and go joint pain, hair loss, fever (up to 103), chills, come and go rash, and now red eyes. He’s on a reduced dose (6 pills a day) and the side effects are much better. He’s doesn’t take any OTC meds…his liver levels seem to go up whenever he adds any other meds in. Check with your doctor before starting anything.
                    • March 6, 2012 at 4:05 pm
                    davidfromsingapore
                    Participant

                      Hi Kellie

                       

                      Been on Zelboraf since November 2011.  My main side effect is fatigue.  I'm tired all the time – which is very unlike the old me.  Also – I've been having a fair number of headaches and a bit of numbness in my hands and feet.  Worst of all – the drug is not working for me.  I found out that my brain mets have returned and now I will need to try a new chemo drug.  Not trying to depress you – I've read that Zelboraf is having Amazing results in most patients.  Sending positive thoughts your way. 

                       

                      David

                      • March 6, 2012 at 4:05 pm
                      davidfromsingapore
                      Participant

                        Hi Kellie

                         

                        Been on Zelboraf since November 2011.  My main side effect is fatigue.  I'm tired all the time – which is very unlike the old me.  Also – I've been having a fair number of headaches and a bit of numbness in my hands and feet.  Worst of all – the drug is not working for me.  I found out that my brain mets have returned and now I will need to try a new chemo drug.  Not trying to depress you – I've read that Zelboraf is having Amazing results in most patients.  Sending positive thoughts your way. 

                         

                        David

                        • March 6, 2012 at 4:05 pm
                        davidfromsingapore
                        Participant

                          Hi Kellie

                           

                          Been on Zelboraf since November 2011.  My main side effect is fatigue.  I'm tired all the time – which is very unlike the old me.  Also – I've been having a fair number of headaches and a bit of numbness in my hands and feet.  Worst of all – the drug is not working for me.  I found out that my brain mets have returned and now I will need to try a new chemo drug.  Not trying to depress you – I've read that Zelboraf is having Amazing results in most patients.  Sending positive thoughts your way. 

                           

                          David

                      Viewing 8 reply threads
                      • You must be logged in to reply to this topic.
                      About the MRF Patient Forum

                      The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                      The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.