cjs

HI – so glad to hear your MRI results were good. I've been reading through this post trying to gather info for my sister who is in a similar situation. She has been on Zelboraf since the fall for mets in lung and breast and is having continued great response in those areas but now has multiple small brain mets (>10). She is currently doing WBRT and her doctors are talking about restarting Zelboraf or starting the Dabrafenib/tramatinib combo. Just wondering if your doctors also gave you the option of Ipilimumab? Or any other options (any clinical trials accepting patients with brain mets?). It is certianly good to hear that you and others are having good responses to dabrafenib after already being on Zelboraf. She is not having repeat scans for another 6 weeks (not sure if this is typical after WBRT) but I think the plan is to start back on some type of systemic therapy as soon as the radiation is done next week. Any further info would be appreciated!

HI – so glad to hear your MRI results were good. I've been reading through this post trying to gather info for my sister who is in a similar situation. She has been on Zelboraf since the fall for mets in lung and breast and is having continued great response in those areas but now has multiple small brain mets (>10). She is currently doing WBRT and her doctors are talking about restarting Zelboraf or starting the Dabrafenib/tramatinib combo. Just wondering if your doctors also gave you the option of Ipilimumab? Or any other options (any clinical trials accepting patients with brain mets?). It is certianly good to hear that you and others are having good responses to dabrafenib after already being on Zelboraf. She is not having repeat scans for another 6 weeks (not sure if this is typical after WBRT) but I think the plan is to start back on some type of systemic therapy as soon as the radiation is done next week. Any further info would be appreciated!

HI – so glad to hear your MRI results were good. I've been reading through this post trying to gather info for my sister who is in a similar situation. She has been on Zelboraf since the fall for mets in lung and breast and is having continued great response in those areas but now has multiple small brain mets (>10). She is currently doing WBRT and her doctors are talking about restarting Zelboraf or starting the Dabrafenib/tramatinib combo. Just wondering if your doctors also gave you the option of Ipilimumab? Or any other options (any clinical trials accepting patients with brain mets?). It is certianly good to hear that you and others are having good responses to dabrafenib after already being on Zelboraf. She is not having repeat scans for another 6 weeks (not sure if this is typical after WBRT) but I think the plan is to start back on some type of systemic therapy as soon as the radiation is done next week. Any further info would be appreciated!