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FeistyD

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      FeistyD
      Participant

        I highly recommend Dr. Hamid at the Angeles Clinic. They are currently conducting clinical trials with anti-PD-1 drugs that are showing great success with metastatic melanoma. It is also a very friendly, caring place. 

        Also Dr. Antoni Ribas at UCLA is a world expert and also involved with the immunotherapy research.

         

        http://www.theangelesclinic.org/

        http://www.mercknewsroom.com/press-release/research-and-development-news/merck-presents-early-stage-interim-data-mk-3475-investig

        FeistyD
        Participant

          I highly recommend Dr. Hamid at the Angeles Clinic. They are currently conducting clinical trials with anti-PD-1 drugs that are showing great success with metastatic melanoma. It is also a very friendly, caring place. 

          Also Dr. Antoni Ribas at UCLA is a world expert and also involved with the immunotherapy research.

           

          http://www.theangelesclinic.org/

          http://www.mercknewsroom.com/press-release/research-and-development-news/merck-presents-early-stage-interim-data-mk-3475-investig

          FeistyD
          Participant

            I highly recommend Dr. Hamid at the Angeles Clinic. They are currently conducting clinical trials with anti-PD-1 drugs that are showing great success with metastatic melanoma. It is also a very friendly, caring place. 

            Also Dr. Antoni Ribas at UCLA is a world expert and also involved with the immunotherapy research.

             

            http://www.theangelesclinic.org/

            http://www.mercknewsroom.com/press-release/research-and-development-news/merck-presents-early-stage-interim-data-mk-3475-investig

            FeistyD
            Participant

              I am in a trial for Merck 3475 (anti-PD-1) for NSCLC; however, everyone else I have met at my clinic is there for the melanoma arm of the trial. They (and I) have had remarkable success (my tumours have shrunk by over 75% in just six months with no side effects). If it's a Phase I trial everyone gets the drug: I have heard the BMS  anti-PD-1 drug is about to go to Phase III trials, which means half get the drug. My doctor is giving a talk on his results with the Merck drug this Sunday at the Society for Melanoma Research International Congress- you may want to check it out online. Not everyone responds to anti-PD-1, but if they do, the response is amazing. There are some markers on one's tumor (PD-L1) which seem to determine one's chance of response; if your tumor doesn't express it, you won't respond. Yervoy is not the same drug, so I think you can fail yervoy and respond to anti-PD-1. The doctors really need to address that question, however. All I can say is anti-PD-1 is saving my life.

              FeistyD
              Participant

                I am in a trial for Merck 3475 (anti-PD-1) for NSCLC; however, everyone else I have met at my clinic is there for the melanoma arm of the trial. They (and I) have had remarkable success (my tumours have shrunk by over 75% in just six months with no side effects). If it's a Phase I trial everyone gets the drug: I have heard the BMS  anti-PD-1 drug is about to go to Phase III trials, which means half get the drug. My doctor is giving a talk on his results with the Merck drug this Sunday at the Society for Melanoma Research International Congress- you may want to check it out online. Not everyone responds to anti-PD-1, but if they do, the response is amazing. There are some markers on one's tumor (PD-L1) which seem to determine one's chance of response; if your tumor doesn't express it, you won't respond. Yervoy is not the same drug, so I think you can fail yervoy and respond to anti-PD-1. The doctors really need to address that question, however. All I can say is anti-PD-1 is saving my life.

                FeistyD
                Participant

                  I am in a trial for Merck 3475 (anti-PD-1) for NSCLC; however, everyone else I have met at my clinic is there for the melanoma arm of the trial. They (and I) have had remarkable success (my tumours have shrunk by over 75% in just six months with no side effects). If it's a Phase I trial everyone gets the drug: I have heard the BMS  anti-PD-1 drug is about to go to Phase III trials, which means half get the drug. My doctor is giving a talk on his results with the Merck drug this Sunday at the Society for Melanoma Research International Congress- you may want to check it out online. Not everyone responds to anti-PD-1, but if they do, the response is amazing. There are some markers on one's tumor (PD-L1) which seem to determine one's chance of response; if your tumor doesn't express it, you won't respond. Yervoy is not the same drug, so I think you can fail yervoy and respond to anti-PD-1. The doctors really need to address that question, however. All I can say is anti-PD-1 is saving my life.

                  FeistyD
                  Participant

                    Hi Kathy, I am on the Merck anti-PD-1 trial in Los Angeles. I actually don't have melanoma, I have Stage IV lung cancer, but I don't know anyone else with lung cancer in the trial, so here I am on your melanoma site. I started in May, and just had my twelve-week scans. So far, I feel great and have had no side effects. My hair is growing back and I almost feel normal. Best of all, I am happy to report almost 70% shrinkage of my tumors with no new mets! We are all very excited at my response (by we, I mean the head of research, the nurses, and my family of course). I would love to keep in touch with others on the trial.

                     I have heard sometimes the first set of scans do not show great progress due to inflammation and other factors, but the next set might be much more promising. For the first time since this whole nightmare began, I have some hope, which is AWESOME!yes

                    FeistyD
                    Participant

                      Hi Kathy, I am on the Merck anti-PD-1 trial in Los Angeles. I actually don't have melanoma, I have Stage IV lung cancer, but I don't know anyone else with lung cancer in the trial, so here I am on your melanoma site. I started in May, and just had my twelve-week scans. So far, I feel great and have had no side effects. My hair is growing back and I almost feel normal. Best of all, I am happy to report almost 70% shrinkage of my tumors with no new mets! We are all very excited at my response (by we, I mean the head of research, the nurses, and my family of course). I would love to keep in touch with others on the trial.

                       I have heard sometimes the first set of scans do not show great progress due to inflammation and other factors, but the next set might be much more promising. For the first time since this whole nightmare began, I have some hope, which is AWESOME!yes

                      FeistyD
                      Participant

                        Hi Kathy, I am on the Merck anti-PD-1 trial in Los Angeles. I actually don't have melanoma, I have Stage IV lung cancer, but I don't know anyone else with lung cancer in the trial, so here I am on your melanoma site. I started in May, and just had my twelve-week scans. So far, I feel great and have had no side effects. My hair is growing back and I almost feel normal. Best of all, I am happy to report almost 70% shrinkage of my tumors with no new mets! We are all very excited at my response (by we, I mean the head of research, the nurses, and my family of course). I would love to keep in touch with others on the trial.

                         I have heard sometimes the first set of scans do not show great progress due to inflammation and other factors, but the next set might be much more promising. For the first time since this whole nightmare began, I have some hope, which is AWESOME!yes

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