pbnjelley

I'm also taking Zelboraf.  I've been on (and off) of it for 2 months now.  It was right after the one week mark (4 pills twice a day) when I started getting the severe joint pain and muscle aches. I also got a severe rash.  I tried to tough it out for a couple days and took some pain pills and slathered on the hydrocortisone creme.  Finally, it was too much and I went in.  My oncologist took me off Zelboraf for about a week and I took a steroid.  Everything got better and we decided to lower the dosage (lowered to 3 pills twice a day) that I was on.    Again, after about a week I became absolutely miserable and this time my oncologist took me off for only a couple days and lowered my dosage again.  Now I am on 2 pills twice a day and I am doing substantially better.  I still have the joint pain but ibuprofen helps and oddly enough I swear by a vet liniment that's used on horses and smells like icy-hot but is much more effective.  I believe its called Absorbine Veterinarian Liniment and I tell you what, this stuff is amazing!!! My family used it all through our athletic years in high school for anything from a sore muscle to a jammed finger and I use it now and it instantly helps with the joint pain.  Be prepared to smell like the strongest icy-hot ever (I actually like to apply it after I get home from work so I'm not bothering too many people with that strong of a smell all day).  I'm hoping that lowering my dosage won't affect the effectiveness of Zelboraf and my oncologist assures me that he doesn't believe it will be a problem but I know that I would not be able to leave my bed if I was on the original dosage.  And if my scans at the end of the month show that it is working, my oncologist has said that we might try to go back to the higher dosage to really kick this thing in the butt.  My thoughts and prayers go out to you and your husband and I hope you find what works for him. 

I'm also taking Zelboraf.  I've been on (and off) of it for 2 months now.  It was right after the one week mark (4 pills twice a day) when I started getting the severe joint pain and muscle aches. I also got a severe rash.  I tried to tough it out for a couple days and took some pain pills and slathered on the hydrocortisone creme.  Finally, it was too much and I went in.  My oncologist took me off Zelboraf for about a week and I took a steroid.  Everything got better and we decided to lower the dosage (lowered to 3 pills twice a day) that I was on.    Again, after about a week I became absolutely miserable and this time my oncologist took me off for only a couple days and lowered my dosage again.  Now I am on 2 pills twice a day and I am doing substantially better.  I still have the joint pain but ibuprofen helps and oddly enough I swear by a vet liniment that's used on horses and smells like icy-hot but is much more effective.  I believe its called Absorbine Veterinarian Liniment and I tell you what, this stuff is amazing!!! My family used it all through our athletic years in high school for anything from a sore muscle to a jammed finger and I use it now and it instantly helps with the joint pain.  Be prepared to smell like the strongest icy-hot ever (I actually like to apply it after I get home from work so I'm not bothering too many people with that strong of a smell all day).  I'm hoping that lowering my dosage won't affect the effectiveness of Zelboraf and my oncologist assures me that he doesn't believe it will be a problem but I know that I would not be able to leave my bed if I was on the original dosage.  And if my scans at the end of the month show that it is working, my oncologist has said that we might try to go back to the higher dosage to really kick this thing in the butt.  My thoughts and prayers go out to you and your husband and I hope you find what works for him. 

I'm also taking Zelboraf.  I've been on (and off) of it for 2 months now.  It was right after the one week mark (4 pills twice a day) when I started getting the severe joint pain and muscle aches. I also got a severe rash.  I tried to tough it out for a couple days and took some pain pills and slathered on the hydrocortisone creme.  Finally, it was too much and I went in.  My oncologist took me off Zelboraf for about a week and I took a steroid.  Everything got better and we decided to lower the dosage (lowered to 3 pills twice a day) that I was on.    Again, after about a week I became absolutely miserable and this time my oncologist took me off for only a couple days and lowered my dosage again.  Now I am on 2 pills twice a day and I am doing substantially better.  I still have the joint pain but ibuprofen helps and oddly enough I swear by a vet liniment that's used on horses and smells like icy-hot but is much more effective.  I believe its called Absorbine Veterinarian Liniment and I tell you what, this stuff is amazing!!! My family used it all through our athletic years in high school for anything from a sore muscle to a jammed finger and I use it now and it instantly helps with the joint pain.  Be prepared to smell like the strongest icy-hot ever (I actually like to apply it after I get home from work so I'm not bothering too many people with that strong of a smell all day).  I'm hoping that lowering my dosage won't affect the effectiveness of Zelboraf and my oncologist assures me that he doesn't believe it will be a problem but I know that I would not be able to leave my bed if I was on the original dosage.  And if my scans at the end of the month show that it is working, my oncologist has said that we might try to go back to the higher dosage to really kick this thing in the butt.  My thoughts and prayers go out to you and your husband and I hope you find what works for him.